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Advances in survival analysis have facilitated unprecedented flexibility in data modeling, yet there remains a lack of tools for graphically illustrating the influence of continuous covariates on predicted survival outcomes. We propose the…

Applications · Statistics 2024-01-15 Yushu Shi , Liangliang Zhang , Kim-Anh Do , Robert R. Jenq , Christine B. Peterson

Population structure can be modelled by evolutionary graphs, which can have a substantial, but very subtle influence on the fate of the arising mutants. Individuals are located on the nodes of these graphs, competing with each other to…

Populations and Evolution · Quantitative Biology 2018-10-31 Marius Möller , Laura Hindersin , Arne Traulsen

In this paper, we develop a general theory for the estimation of the transition probabilities of reversible Markov chains using the maximum entropy principle. A broad range of physical models can be studied within this approach. We use…

Statistical Mechanics · Physics 2015-05-14 Erik Van der Straeten

Recent literature has found conditional transition rates to be a useful tool for avoiding Markov assumptions in multi-state models. While the estimation of univariate conditional transition rates has been extensively studied, the…

Statistics Theory · Mathematics 2024-08-30 Theis Bathke

Reinforced processes are known to provide a stochastic representation for the quasi-stationary distribution of a given killed Markov process - describing the killed Markov process at fixed time instants. In this paper we shall adapt the…

Probability · Mathematics 2022-02-10 Oliver Tough

Markov branching systems form a fundamental class of stochastic models that are extensively applied in biology, physics, finance, and other domains. These systems are distinguished by their continuous-time evolution and inherent branching…

We introduce a new method for predicting the formation of links in real-world networks, which we refer to as the method of effective transitions. This method relies on the theory of isospectral matrix reductions to compute the probability…

Social and Information Networks · Computer Science 2019-09-04 Bryn Balls-Barker , Benjamin Webb

By generating the specifics of a network structure only when needed (on-the-fly), we derive a simple stochastic process that exactly models the time evolution of susceptible-infectious dynamics on finite-size networks. The small number of…

Statistical Mechanics · Physics 2015-03-18 Pierre-André Noël , Antoine Allard , Laurent Hébert-Dufresne , Vincent Marceau , Louis J. Dubé

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

Survival models are used to analyze time-to-event data in a variety of disciplines. Proportional hazard models provide interpretable parameter estimates, but proportional hazards assumptions are not always appropriate. Non-parametric models…

Methodology · Statistics 2022-07-08 Richard D. Payne , Nilabja Guha , Bani K. Mallick

Decomposable graphs are known for their tedious and complicated Markov update steps. Instead of modelling them directly, this work introduces a class of tree-dependent bipartite graphs that span the projective space of decomposable graphs.…

Methodology · Statistics 2017-10-11 Mohamad Elmasri

In this paper we present the Markov variation, a smoothness measure which offers a probabilistic interpretation of graph signal smoothness. This measure is then used to develop an optimization framework for graph signal interpolation. Our…

Signal Processing · Electrical Eng. & Systems 2020-01-29 Ayelet Heimowitz , Yonina C. Eldar

Diagonalizability plays an important role in the analysis and design of multivariable systems. A structured matrix is called structurally diagonalizable if almost all of its numerical realizations, obtained by assigning real values to its…

Optimization and Control · Mathematics 2026-01-30 Yuan Zhang , Yutong Han , Yuanqing Xia , Aming Li

Direct simulation of biomolecular dynamics in thermal equilibrium is challenging due to the metastable nature of conformation dynamics and the computational cost of molecular dynamics. Biased or enhanced sampling methods may improve the…

Chemical Physics · Physics 2015-06-12 Benjamin Trendelkamp-Schroer , Frank Noe

When analyzing weighted networks using spectral embedding, a judicious transformation of the edge weights may produce better results. To formalize this idea, we consider the asymptotic behavior of spectral embedding for different…

Machine Learning · Statistics 2023-01-23 Ian Gallagher , Andrew Jones , Anna Bertiger , Carey Priebe , Patrick Rubin-Delanchy

We analyze the properties of degree-preserving Markov chains based on elementary edge switchings in undirected and directed graphs. We give exact yet simple formulas for the mobility of a graph (the number of possible moves) in terms of its…

Disordered Systems and Neural Networks · Physics 2012-03-12 E. S. Roberts , A. Annibale , A. C. C. Coolen

We present the probability preserving description of the decaying particle within the framework of quantum mechanics of open systems taking into account the superselection rule prohibiting the superposition of the particle and vacuum. In…

Quantum Physics · Physics 2007-05-23 P. Caban , J. Rembielinski , K. A. Smolinski , Z. Walczak

This work presents a construction of stationary Markov models with negative-binomial marginal distributions. A simple closed form expression for the corresponding transition probabilities is given, linking the proposal to well-known classes…

Methodology · Statistics 2019-04-10 Fabrizio Leisen , Ramsés H. Mena , Freddy Palma Mancilla , Luca Rossini

In this paper, we explore a method for treating survival analysis as a classification problem. The method uses a "stacking" idea that collects the features and outcomes of the survival data in a large data frame, and then treats it as a…

Methodology · Statistics 2019-09-27 Chenyang Zhong , Robert Tibshirani

Evolutionary graph theory studies the evolutionary dynamics of populations structured on graphs. A central problem is determining the probability that a small number of mutants overtake a population. Currently, Monte Carlo simulations are…

Computer Science and Game Theory · Computer Science 2013-01-14 Paulo Shakarian , Patrick Roos , Geoffrey Moores