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Related papers: Microdosimetry of radiation field from therapeutic…

200 papers

A Geant4-based Monte Carlo model for Heavy-Ion Therapy (MCHIT) is used to study radiation fields of H-1, He-4, Li-7 and C-12 beams with similar ranges (~160-180 mm) in water. Microdosimetry spectra are simulated for wall-less and walled…

Medical Physics · Physics 2014-02-10 Lucas Burigo , Igor Pshenichnov , Igor Mishustin , Marcus Bleicher

We study energy deposition by light nuclei in tissue-like media taking into account nuclear fragmentation reactions, in particular, production of secondary neutrons. The calculations are carried out within a Monte Carlo model for Heavy-Ion…

Medical Physics · Physics 2007-05-23 Igor Pshenichnov , Igor Mishustin , Walter Greiner

We study the propagation of nucleons and nuclei in tissue-like media within a Monte Carlo Model for Heavy-ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.2). The model takes into account fragmentation of projectile nuclei and…

Medical Physics · Physics 2010-11-03 Igor Pshenichnov , Igor Mishustin , Walter Greiner

We used the GEANT4 Monte Carlo MC Toolkit to simulate carbon ion beams incident on water, tissue, and bone, taking into account nuclear fragmentation reactions. Upon increasing the energy of the primary beam, the position of the Bragg-Peak…

Medical Physics · Physics 2021-02-26 M. Kh. Hamad

We study the spatial distributions of $\beta^+$-activity produced by therapeutic beams of $^3$He and $^{12}$C ions in various tissue-like materials. The calculations were performed within a Monte Carlo model for Heavy-Ion Therapy (MCHIT)…

Medical Physics · Physics 2010-11-03 Igor Pshenichnov , Alexei Larionov , Igor Mishustin , Walter Greiner

A proton pencil beam is associated with a surrounding low-dose envelope, originating from nuclear interactions. It is important for treatment planning systems to accurately model this envelope when performing dose calculations for pencil…

Medical Physics · Physics 2015-11-30 David C. Hall , Anastasia Makarova , Harald Paganetti , Bernard Gottschalk

In carbon-therapy, the interaction of the incoming beam with human tissues may lead to the production of a large amount of nuclear fragments and secondary light particles. An accurate estimation of the biological dose deposited into the…

Nuclear Experiment · Physics 2014-06-02 J. Dudouet , D. Cussol , D. Durand , M. Labalme

We study the energy deposition by light and heavy nuclei in tissue-like media as used for cancer therapy. The depth-dose distributions for protons, $^{3}$He, $^{12}$C, $^{20}$Ne, and $^{58}$Ni nuclei are calculated within a Monte Carlo…

Medical Physics · Physics 2010-11-03 Igor Pshenichnov , Igor Mishustin , Walter Greiner

Depth distributions of positron-emitting nuclei in PMMA phantoms are calculated within a Monte Carlo model for Heavy-Ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.0). The calculated total production rates of $^{11}$C, $^{10}$C…

Medical Physics · Physics 2007-05-23 Igor Pshenichnov , Igor Mishustin , Walter Greiner

Beams of $^{4}$He and $^{16}$O nuclei are considered for ion-beam cancer therapy as alternative options to protons and $^{12}$C nuclei. Spread-out Bragg peak (SOBP) distributions of physical dose and relative biological effectiveness for…

Medical Physics · Physics 2015-06-19 Lucas Burigo , Igor Pshenichnov , Igor Mishustin , Marcus Bleicher

This study investigates the influence of several Monte Carlo radiation transport codes and nuclear models on the simulation of secondary neutron spectra and its impact on calculating and measuring neutron doses in proton therapy. Three…

Arrays of minibeams of protons and $^{12}$C in tissue-like media were modeled with Geant4 toolkit. A set of beam energies was used in simulations to provide a Spead-out Bragg peak (SOBP) extended by 6 cm in depth for protons as well as for…

Medical Physics · Physics 2024-09-23 I. A. Pshenichnov , U. A. Dmitrieva , S. D. Savenkov , A. O. Svetlichnyi

Treating cancer is one of the most challenging task in medical sciences. Only limited types of cancer treatments are available as their study is still ongoing. The earlier therapies like radiotherapy with x-rays, chemotherapy are associated…

Accelerator Physics · Physics 2024-06-06 R. Kanishka

During therapeutic treatments using ions such as carbon, nuclear interactions between the incident ions and nuclei present in organic tissues may occur, leading to the attenuation of the incident beam intensity and to the production of…

Nuclear Experiment · Physics 2014-07-02 J. Dudouet , M. Labalme , D. Cussol , C. Finck , R. Rescigno , M. Rousseau , S. Salvador , M. Vanstalle

Nowadays there is a growing interest in Particle Therapy treatments exploiting light ion beams against tumors due to their enhanced Relative Biological Effectiveness and high space selectivity. In particular promising results are obtained…

The Monte Carlo method is widely used in the Gamma Knife dose distribution calculations. In this study, Monte-Carlo simulation with Geant4 was applied to determine Leksell Gamma Knife dose distribution for homogeneous solid water and…

Medical Physics · Physics 2021-01-26 Ozlem Dagli , A. Gunes Tanir , Gokhan Kurt

Purpose: Beam range control is the essence of radiotherapy with heavy charged particles. In conventional broad-beam delivery, fine range adjustment is achieved by insertion of range shifting and compensating materials. In dosimetry, solid…

Medical Physics · Physics 2016-10-03 Nobuyuki Kanematsu , Yusuke Koba , Risa Ogata

Coherent elastic neutrino-nucleus scattering (CEvNS) provides a well-defined framework for studying nuclear recoil observables in low-energy neutrino interactions. In this work, we present a comparative Monte Carlo benchmark study of…

High Energy Physics - Experiment · Physics 2026-02-05 Yusuf Havvat

The capability of standard Geant4 PhysicsLists to address the fragmentation of $^{12}$C$-^{12}$C was assessed through a comparative analysis with experimental cross sections reported by Divay et al. and Dudouet et al. The standard…

Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

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