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Biclustering is an unsupervised machine-learning approach aiming to cluster rows and columns simultaneously in a data matrix. Several biclustering algorithms have been proposed for handling numeric datasets. However, real-world data mining…

Machine Learning · Computer Science 2024-08-26 Adán José-García , Julie Jacques , Clément Chauvet , Vincent Sobanski , Clarisse Dhaenens

We perform differential expression analysis of high-throughput sequencing count data under a Bayesian nonparametric framework, removing sophisticated ad-hoc pre-processing steps commonly required in existing algorithms. We propose to use…

Applications · Statistics 2017-05-04 Siamak Zamani Dadaneh , Xiaoning Qian , Mingyuan Zhou

Classically, Bayesian clustering interprets each component of a mixture model as a cluster. The inferred clustering posterior is highly sensitive to any inaccuracies in the kernel within each component. As this kernel is made more flexible,…

Methodology · Statistics 2025-12-12 David Buch , Miheer Dewaskar , David B. Dunson

A critical step of genome sequence analysis is the mapping of sequenced DNA fragments (i.e., reads) collected from an individual to a known linear reference genome sequence (i.e., sequence-to-sequence mapping). Recent works replace the…

We here present SIMLR (Single-cell Interpretation via Multi-kernel LeaRning), an open-source tool that implements a novel framework to learn a sample-to-sample similarity measure from expression data observed for heterogenous samples. SIMLR…

Genomics · Quantitative Biology 2018-01-22 Bo Wang , Daniele Ramazzotti , Luca De Sano , Junjie Zhu , Emma Pierson , Serafim Batzoglou

We propose a practical Bayesian optimization method over sets, to minimize a black-box function that takes a set as a single input. Because set inputs are permutation-invariant, traditional Gaussian process-based Bayesian optimization…

Machine Learning · Statistics 2021-01-26 Jungtaek Kim , Michael McCourt , Tackgeun You , Saehoon Kim , Seungjin Choi

Traditional clustering methods are limited when dealing with huge and heterogeneous groups of gene expression data, which motivates the development of bi-clustering methods. Bi-clustering methods are used to mine bi-clusters whose subsets…

Computer Vision and Pattern Recognition · Computer Science 2020-05-13 Kaijie Xu , Witold Pedrycz , Zhiwu Li , Yinghui Quan , Weike Nie

Identifying differentially expressed genes from RNA sequencing data remains a challenging task because of the considerable uncertainties in parameter estimation and the small sample sizes in typical applications. Here we introduce Bayesian…

Applications · Statistics 2014-11-11 Matthias Katzfuss , Andreas Neudecker , Simon Anders , Julien Gagneur

In genomics, differential abundance and expression analyses are complicated by the compositional nature of sequence count data, which reflect only relative-not absolute-abundances or expression levels. Many existing methods attempt to…

Methodology · Statistics 2025-12-16 Won Gu , Francesca Chiaromonte , Justin D. Silverman

Using a Bayesian network to analyze the causal relationship between nodes is a hot spot. The existing network learning algorithms are mainly constraint-based and score-based network generation methods. The constraint-based method is mainly…

Machine Learning · Computer Science 2022-12-07 Baokui Mou

In the past few years powerful generalizations to the Euclidean k-means problem have been made, such as Bregman clustering [7], co-clustering (i.e., simultaneous clustering of rows and columns of an input matrix) [9,18], and tensor…

Data Structures and Algorithms · Computer Science 2009-11-09 Stefanie Jegelka , Suvrit Sra , Arindam Banerjee

This paper concerns pseudo labelling in segmentation. Our contribution is fourfold. Firstly, we present a new formulation of pseudo-labelling as an Expectation-Maximization (EM) algorithm for clear statistical interpretation. Secondly, we…

Computer Vision and Pattern Recognition · Computer Science 2022-09-14 Mou-Cheng Xu , Yukun Zhou , Chen Jin , Marius de Groot , Daniel C. Alexander , Neil P. Oxtoby , Yipeng Hu , Joseph Jacob

Identification of every single genome present in a microbial sample is an important and challenging task with crucial applications. It is challenging because there are typically millions of cells in a microbial sample, the vast majority of…

Genomics · Quantitative Biology 2014-04-29 Zeinab Taghavi , Narjes S. Movahedi , Sorin Draghici , Hamidreza Chitsaz

This presentation describes the Bayesian Block algorithm in the context of its application to analysis of time series data from the Fermi Gamma Ray Space Telescope. More generally this algorithm performs optimal segmentation analysis on…

Instrumentation and Methods for Astrophysics · Physics 2013-05-28 Jeffrey D. Scargle , Jay P. Norris , Brad Jackson , James Chiang

To solve the Grammatical Error Correction (GEC) problem , a mapping between a source sequence and a target one is needed, where the two differ only on few spans. For this reason, the attention has been shifted to the non-autoregressive or…

Computation and Language · Computer Science 2024-10-23 Kamal Al-Sabahi , Kang Yang , Wangwang Liu , Guanyu Jiang , Xian Li , Ming Yang

Single-cell RNA sequencing (scRNA-seq) data analysis is pivotal for understanding cellular heterogeneity. However, the high sparsity and complex noise patterns inherent in scRNA-seq data present significant challenges for traditional…

Genomics · Quantitative Biology 2024-08-13 Wenwen Min , Zhen Wang , Fangfang Zhu , Taosheng Xu , Shunfang Wang

This article concerns testing for equality of distribution between groups. We focus on screening variables with shared distributional features such as common support, modes and patterns of skewness. We propose a Bayesian testing method…

Methodology · Statistics 2016-02-19 Eric F. Lock , David B. Dunson

In this letter, a binary sparse Bayesian learning (BSBL) algorithm is proposed to slove the one-bit compressed sensing (CS) problem in both single measurement vector (SMV) and multiple measurement vectors (MMVs). By utilising the…

Information Theory · Computer Science 2018-05-09 Jiang Zhu , Lin Han , Xiangming Meng , Zhiwei Xu

Bayesian clustering typically relies on mixture models, with each component interpreted as a different cluster. After defining a prior for the component parameters and weights, Markov chain Monte Carlo (MCMC) algorithms are commonly used to…

Methodology · Statistics 2024-07-30 Alexander Dombowsky , David B. Dunson

Ensemble clustering integrates a set of base clustering results to generate a stronger one. Existing methods usually rely on a co-association (CA) matrix that measures how many times two samples are grouped into the same cluster according…

Machine Learning · Computer Science 2023-02-24 Yuheng Jia , Sirui Tao , Ran Wang , Yongheng Wang