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Co-localization of networks of genes in the nucleus is thought to play an important role in determining gene expression patterns. Based upon experimental data, we built a dynamical model to test whether pure diffusion could account for the…

Molecular Networks · Quantitative Biology 2012-03-06 Jing Kang , Bing Xu , Ye Yao , Wei Lin , Conor Hennessy , Peter Fraser , Jianfeng Feng

The presence of nanoparticles in a diblock copolymer leads to changes in the morphology and properties of the matrix and can produce highly organized hybrid materials. The resulting material properties depend not only on the polymer…

Soft Condensed Matter · Physics 2018-05-30 Javier Diaz , Marco Pinna , Andrei Zvelindovsky , Adelchi Asta , Ignacio Pagonabarraga

How to artificially encode observer in universal information coding structure like DNA ? It requires naturally creating information Bits and natural encoding triplet code enables recognizing other encoded information. These Bits become…

General Physics · Physics 2019-07-30 Vladimir S. Lerner

Motivated by the problem of domain formation in chromosomes, we studied a co--polymer model where only a subset of the monomers feel attractive interactions. These monomers are displaced randomly from a regularly-spaced pattern, thus…

Biomolecules · Quantitative Biology 2018-02-13 Matteo Negri , Marco Gherardi , Guido Tiana , Marco Cosentino Lagomarsino

We present a mathematical and computational framework for the problem of learning a dynamical system from noisy observations of a few trajectories and subject to side information. Side information is any knowledge we might have about the…

Optimization and Control · Mathematics 2022-01-19 Amir Ali Ahmadi , Bachir El Khadir

What does the informational complexity of dynamical networked systems tell us about intrinsic mechanisms and functions of these complex systems? Recent complexity measures such as integrated information have sought to operationalize this…

Neural and Evolutionary Computing · Computer Science 2017-07-06 Xerxes D. Arsiwalla , Pedro A. M. Mediano , Paul F. M. J. Verschure

We illustrate the use of tools (asymptotic theories of standard error quantification using appropriate statistical models, bootstrapping, model comparison techniques) in addition to sensitivity that may be employed to determine the…

Analysis of PDEs · Mathematics 2015-03-17 H. T. Banks , M Doumic , C Kruse , S Prigent , H Rezaei

In a previous paper [1] we considered the question, "What underlying property of nature is responsible for the second law?" A simple answer can be stated in terms of information: The fundamental loss of information gives rise to the second…

Statistical Mechanics · Physics 2012-02-21 T. L. Duncan , J. S. Semura

Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a…

Populations and Evolution · Quantitative Biology 2012-07-25 Christoph Adami

For substitutional alloys, typically refered to as classical discrete systems under constant composition, we theoretically examine the role of hidden structure information on evolution of nonlinearity (i.e., correspondence between a set of…

Statistical Mechanics · Physics 2022-02-25 Koretaka Yuge

The dynamics of biological polymers, including proteins, RNA, and DNA, occur in very high-dimensional spaces. Many naturally-occurring polymers can navigate a vast phase space and rapidly find their lowest free energy (folded) state. Thus,…

Computational Physics · Physics 2024-06-19 Frederico Campos Freitas , Sandra Byju , Asem Hassan , Ronaldo Junio de Oliveira , Paul C. Whitford

The framework of bipartite stochastic thermodynamics is a powerful tool to analyze a composite system's internal thermodynamics. It has been used to study the components of different molecular machines such as ATP synthase. However, this…

Statistical Mechanics · Physics 2026-04-15 Julian D. Jiménez-Paz , Matthew P. Leighton , David A. Sivak

The constituents of a complex system exchange information to function properly. Their signalling dynamics often leads to the appearance of emergent phenomena, such as phase transitions and collective behaviors. While information exchange…

Physics and Society · Physics 2020-11-18 Arsham Ghavasieh , Carlo Nicolini , Manlio De Domenico

Part 1 has studied the conversion of observed random process with its hidden information to related dynamic process, applying entropy functional measure (EF) of the random process and path functional information measure (IPF) of the dynamic…

Adaptation and Self-Organizing Systems · Physics 2013-08-20 Vladimir S. Lerner

Vitrimers are polymer networks that can undergo bond exchange reactions. They dynamically rearrange their structures while maintaining their overall integrity, thus resulting in unique properties such as self-healing, reprocessability,…

Soft Condensed Matter · Physics 2024-02-27 Rahul Karmakar , Himanshu , Srikanth Sastry , Sanat K Kumar , Tarak K Patra

A large number of studies have shown the existence of metabolic covalent modifications in different molecular structures, able to store biochemical information that is not encoded by the DNA. Some of these covalent mark patterns can be…

Subcellular Processes · Quantitative Biology 2015-01-12 Ildefonso M. De la Fuente

This paper investigates the coexistence of positive and negative information in the context of information-epidemic dynamics on multiplex networks. In accordance with the tenets of mean field theory, we present not only the analytic…

Physics and Society · Physics 2025-10-27 Li-Ying Liu , Chao-Ran Cai , Si-Ping Zhang , Bin-Quan Li

We show that the conservation and the non-additivity of the information, together with the additivity of the entropy make the entropy increase in an isolated system. The collapse of the entangled quantum state offers an example of the…

Quantum Physics · Physics 2009-11-13 Qi-Ren Zhang

Stochastic forces in natural systems are rarely isotropic. From hydrodynamically coupled colloids to chemical reaction networks, noise contributions are inherently correlated. Together with internal interactions and changing environments,…

Statistical Mechanics · Physics 2026-05-14 Andrea Marchetti , Daniel Maria Busiello , Giorgio Nicoletti

Physical systems behave according to their underlying dynamical equations which, in turn, can be identified from experimental data. Explaining data requires selecting mathematical models that best capture the data regularities. Identifying…

Data Analysis, Statistics and Probability · Physics 2014-03-18 Carlo Cafaro