English
Related papers

Related papers: Optimum Experimental Design for EGDM Modeled Organ…

200 papers

Ordinary differential equation (ODE) models are widely used to describe systems in many areas of science. To ensure these models provide accurate and interpretable representations of real-world dynamics, it is often necessary to infer…

Methodology · Statistics 2026-03-24 Selva Salimi , David J. Warne , Christopher Drovandi

Although freeform devices with complex internal structures promise drastic increases in performance, the discreteness of the set of available materials presents challenges for gradient-based optimization necessary for the efficient…

Optimization and Control · Mathematics 2025-11-10 Seokhwan Min , Junhyung Park , Jonghwa Shin

We propose a novel approach for sequential optimal experimental design (sOED) for Bayesian inverse problems involving expensive models with high-dimensional unknown parameters. This work focuses on designs that maximize the expected…

Optimization and Control · Mathematics 2026-05-05 Tiangang Cui , Karina Koval , Roland Herzog , Robert Scheichl

We consider the problem of computing optimal experimental design on a finite design space with respect to a compound Bayes risk criterion, which includes the linear criterion for prediction in a random coefficient regression model. We show…

Computation · Statistics 2017-09-08 Radoslav Harman , Maryna Prus

Koopman operator theory shows how nonlinear dynamical systems can be represented as an infinite-dimensional, linear operator acting on a Hilbert space of observables of the system. However, determining the relevant modes and eigenvalues of…

Machine Learning · Computer Science 2022-04-06 Daniel J. Alford-Lago , Christopher W. Curtis , Alexander T. Ihler , Opal Issan

The paper focuses on unconditionally optimal error analysis of the fully discrete Galerkin finite element methods for a general nonlinear parabolic system in $\R^d$ with $d=2,3$. In terms of a corresponding time-discrete system of PDEs as…

Numerical Analysis · Mathematics 2013-03-27 Buyang Li , Weiwei Sun

Design of experiments is a fundamental topic in applied statistics with a long history. Yet its application is often limited by the complexity and costliness of constructing experimental designs, which involve searching a high-dimensional…

Methodology · Statistics 2022-03-29 Matthew T. Pratola , C. Devon Lin , Peter F. Craigmile

There is a growing trend in molecular and synthetic biology of using mechanistic (non machine learning) models to design biomolecular networks. Once designed, these networks need to be validated by experimental results to ensure the…

Quantitative Methods · Quantitative Biology 2020-11-26 Ruby Sedgwick , John Goertz , Molly Stevens , Ruth Misener , Mark van der Wilk

Recent advances in nanotechnology have enabled researchers to manipulate small collections of quantum mechanical objects with unprecedented accuracy. In semiconductor quantum dot qubits, this manipulation requires controlling the dot…

Mesoscale and Nanoscale Physics · Physics 2019-03-06 Adam Frees , John King Gamble , Daniel R. Ward , Robin Blume-Kohout , M. A. Eriksson , Mark Friesen , S. N. Coppersmith

Efficient modeling of High Temperature Superconductors (HTSs) is crucial for real-time quench monitoring; however, full-order electromagnetic simulations remain prohibitively costly due to the strong nonlinearities. Conventional…

Computational Engineering, Finance, and Science · Computer Science 2026-02-17 Riccardo Basei , Francesco Pase , Francesco Lucchini , Francesco Toso , Riccardo Torchio

In this paper, we apply a specifically designed dissipative spatial filter as sub-grid scale model within the increasingly popular discontinuous Galerkin methods and the closely related flux reconstruction high order methods for large eddy…

Computational Engineering, Finance, and Science · Computer Science 2020-02-19 David G Flad , Andrea D Beck , Philipp Guthke

In this work, we investigate the performance CutFEM as a high fidelity solver as well as we construct a competent and economical reduced order solver for PDE-constrained optimization problems in parametrized domains that live in a fixed…

Numerical Analysis · Mathematics 2022-04-11 Georgios Katsouleas , Efthymios N. Karatzas , Fotios Travlopanos

Machine-designed control of complex devices or experiments can discover strategies superior to those developed via simplified models. We describe an online optimization algorithm based on Gaussian processes and apply it to optimization of…

In experimental design, we are given $n$ vectors in $d$ dimensions, and our goal is to select $k\ll n$ of them to perform expensive measurements, e.g., to obtain labels/responses, for a linear regression task. Many statistical criteria have…

Machine Learning · Computer Science 2019-06-11 Michał Dereziński , Feynman Liang , Michael W. Mahoney

Applications of Bose-Einstein Condensates (BEC) often require that the condensate be prepared in a specific complex state. Optimal control is a reliable framework to prepare such a state while avoiding undesirable excitations, and, when…

Quantum Gases · Physics 2022-03-14 Jimmie Adriazola , Roy H. Goodman

Enlightened from the inverse consideration of the stable continuous-time dynamics evolution, the Variation Evolving Method (VEM) analogizes the optimal solution to the equilibrium point of an infinite-dimensional dynamic system and solves…

Systems and Control · Computer Science 2018-01-08 Sheng Zhang , Bo Liao , Fei Liao

We study the problem of estimating a function of many parameters acquired by sensors that are distributed in space, e.g., the spatial gradient of a field. We restrict ourselves to a setting where the distributed sensors are probed with…

Quantum Physics · Physics 2018-10-03 T. J. Volkoff , Mohan Sarovar

This paper presents a quasi-sequential optimal design framework for toxicology experiments, specifically applied to sea urchin embryos. The authors propose a novel approach combining robust optimal design with adaptive, stage-based testing…

Methodology · Statistics 2025-03-04 Elvis Han Cui , Michael Collins , Jessica Munson , Weng Kee Wong

Finding the best setup for experiments is the primary concern for Optimal Experimental Design (OED). Here, we focus on the Bayesian experimental design problem of finding the setup that maximizes the Shannon expected information gain. We…

Numerical Analysis · Mathematics 2020-02-28 Andre Gustavo Carlon , Ben Mansour Dia , Luis FR Espath , Rafael Holdorf Lopez , Raul Tempone

Improving and optimizing oceanographic sampling is a crucial task for marine science and maritime resource management. Faced with limited resources in understanding processes in the water-column, the combination of statistics and autonomous…

Applications · Statistics 2020-08-19 Trygve Olav Fossum , Cédric Travelletti , Jo Eidsvik , David Ginsbourger , Kanna Rajan