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Fluctuations in heart rate are intimately tied to changes in the physiological state of the organism. We examine and exploit this relationship by classifying a human subject's wake/sleep status using his instantaneous heart rate (IHR)…

Applications · Statistics 2018-08-02 John Malik , Yu-Lun Lo , Hau-tieng Wu

Hebbian learning theory is rooted in Pavlov's Classical Conditioning. While mathematical models of the former have been proposed and studied in the past decades, especially in spin glass theory, only recently it has been numerically shown…

Disordered Systems and Neural Networks · Physics 2024-10-11 Daniele Lotito , Miriam Aquaro , Chiara Marullo

The state of many physical, biological and socio-technical systems evolves by combining smooth local transitions and abrupt resetting events to a set of reference values. The inclusion of the resetting mechanism not only provides the…

Statistical Mechanics · Physics 2022-12-21 Oriol Artime

Multistability -- the emergence of multiple stable states under identical conditions -- is a hallmark of nonlinear complexity and an enabling mechanism for multilevel optical memory and photonic computing. Its realization in a compact…

Optics · Physics 2025-11-18 Zhen Liu , Xuefan Yin , Andrey Bogdanov , Yujia Nie , Yi Zuo , Hongbin Li , Feifan Wang , Chao Peng

Circadian clocks are the central timekeepers of life, allowing cells to anticipate changes between day and night. Experiments in recent years have revealed that circadian clocks can be highly stable, raising the question how reliably they…

Molecular Networks · Quantitative Biology 2016-06-22 Michele Monti , Pieter Rein ten Wolde

Sleep is critical to leading a healthy lifestyle. Each day, most people go to sleep without any idea about how their night's rest is going to be. For an activity that humans spend around a third of their life doing, there is a surprising…

Computers and Society · Computer Science 2020-06-22 Dhruv Upadhyay , Vaibhav Pandey , Nitish Nag , Ramesh Jain

Understanding the sleep quality and architecture is essential to human being's health, which is usually represented using multiple sleep stages. A standard sleep stage determination requires Electroencephalography (EEG) signals during the…

Signal Processing · Electrical Eng. & Systems 2019-09-26 Yuezhou Zhang , Zhicheng Yang , Ke Lan , Xiaoli Liu , Zhengbo Zhang , Peiyao Li , Desen Cao , Jiewen Zheng , Jianli Pan

Even during fixation the human eye is constantly in low amplitude motion, jittering over small angles in random directions at up to 100Hz. This motion results in all features of the image on the retina constantly traversing a number of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 David W Arathorn , Josephine C. D'Angelo , Austin Roorda

Sleep is characterized by non-rapid eye movement (nREM) sleep, originating from widespread neuronal synchrony, and REM sleep, with neuronal desynchronization akin to waking behavior. While these were thought to be global brain states,…

Neurons and Cognition · Quantitative Biology 2024-05-29 Davor Curic , Surjeet Singh , Mojtaba Nazari , Majid H. Mohajerani , Joern Davidsen

Individual neurons often produce highly variable responses over nominally identical trials, reflecting a mixture of intrinsic "noise" and systematic changes in the animal's cognitive and behavioral state. Disentangling these sources of…

Neurons and Cognition · Quantitative Biology 2021-11-08 Alex H. Williams , Scott W. Linderman

A recent model to analyze the Center of Pressure trajectories is based on the fractional Brownian motion. By doing so, one note that standing still is describe by different mechanisms following the frequency. Previous studies exhibit the…

Medical Physics · Physics 2025-03-31 Pierre R. Bertrand , Jean-Marc Bardet , Michel Dabonneville , A. Mouzat , Philippe Vaslin

In this paper, two modern adaptive signal processing techniques, Empirical Intrinsic Geometry and Synchrosqueezing transform, are applied to quantify different dynamical features of the respiratory and electroencephalographic signals. We…

Medical Physics · Physics 2014-10-07 Hau-tieng Wu , Ronen Talmon , Yu-Lun Lo

Neural synchronization is believed to be critical for many brain functions. It frequently exhibits temporal variability, but it is not known if this variability has a specific temporal patterning. This study explores these…

Neurons and Cognition · Quantitative Biology 2013-03-11 Sungwoo Ahn , Leonid L. Rubchinsky

Neuronal spiking exhibits an exquisite combination of modulation and robustness properties, rarely matched in artificial systems. We exploit the particular interconnection structure of conductance based models to investigate this remarkable…

Neurons and Cognition · Quantitative Biology 2013-11-12 Guillaume Drion , Alessio Franci , Vincent Seutin , Rodolphe Sepulchre

We compare scaling properties of the cardiac dynamics during sleep and wake periods for healthy individuals, cosmonauts during orbital flight, and subjects with severe heart disease. For all three groups, we find a greater degree of…

In the last century, most sensorimotor studies of cortical neurons relied on average firing rates. Rate coding is efficient for fast sensorimotor processing that occurs within a few seconds. Much less is known about the neural mechanisms…

Neurons and Cognition · Quantitative Biology 2026-05-01 Terrence J. Sejnowski

Electroencephalography (EEG) is a method to record the electrical signals in the brain. Recognizing the EEG patterns in the sleeping brain gives insights into the understanding of sleeping disorders. The dataset under consideration contains…

Machine Learning · Statistics 2018-04-25 Aditya Chindhade , Abhijeet Alshi , Aakash Bhatia , Kedar Dabhadkar , Pranav Sivadas Menon

Neural recordings are nonstationary time series, i.e. their properties typically change over time. Identifying specific changes, e.g. those induced by a learning task, can shed light on the underlying neural processes. However, such changes…

Quantitative Methods · Quantitative Biology 2013-01-28 Duncan A. J. Blythe , Frank C. Meinecke , Paul von Buenau , Klaus-Robert Mueller

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

Mixing timescales and residence times in reactive multiphase flows can be essential for product selectivity. For instance when a gas species is consumed e.g. by a competitive consecutive reaction with moderate reaction kinetics where…

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