Related papers: A statistical mechanics approach to the sample dec…
Wideband analog signals push contemporary analog-to-digital conversion systems to their performance limits. In many applications, however, sampling at the Nyquist rate is inefficient because the signals of interest contain only a small…
Structural variants compose the majority of human genetic variation, but are difficult to assess using current genomic sequencing technologies. Optical mapping technologies, which measure the size of chromosomal fragments between labeled…
Background properties in experimental particle physics are typically estimated using control samples corresponding to large numbers of events. This can provide precise knowledge of average background distributions, but typically does not…
Physical mechanisms of phase separation in living systems can play key physiological roles and have recently been the focus of intensive studies. The strongly heterogeneous and disordered nature of such phenomena in the biological domain…
In this paper an extension of the sparse decomposition problem is considered and an algorithm for solving it is presented. In this extension, it is known that one of the shifted versions of a signal s (not necessarily the original signal…
This paper considers convolution equations that arise from problems such as measurement error and non-parametric regression with errors in variables with independence conditions. The equations are examined in spaces of generalized functions…
Fitting a simplifying model with several parameters to real data of complex objects is a highly nontrivial task, but enables the possibility to get insights into the objects physics. Here, we present a method to infer the parameters of the…
Particle filtering is used to compute good nonlinear estimates of complex systems. It samples trajectories from a chosen distribution and computes the estimate as a weighted average. Easy-to-sample distributions often lead to degenerate…
A number of classification problems need to deal with data imbalance between classes. Often it is desired to have a high recall on the minority class while maintaining a high precision on the majority class. In this paper, we review a…
We propose an alternative method to generate samples of a spatially correlated random field with applications to large-scale problems for forward propagation of uncertainty. A classical approach for generating these samples is the…
Approximation theory plays an important role in image processing, especially image deconvolution and decomposition. For piecewise smooth images, there are many methods that have been developed over the past thirty years. The goal of this…
We present a Bayesian hierarchical multi-view mixture model termed Symphony that simultaneously learns clusters of cells representing cell types and their underlying gene regulatory networks by integrating data from two views: single-cell…
We train a neural network to predict distributional responses in gene expression following genetic perturbations. This is an essential task in early-stage drug discovery, where such responses can offer insights into gene function and inform…
In this paper we present a technique to couple non-traditional data with statistics based on survey data, in order to partially correct for the bias produced by non-random sample selections. All major social media platforms represent huge…
We develop $M$-estimation and deconvolution methodology with the goal of making well-founded statistical inference on an individual's blood alcohol level based on noisy measurements of their skin alcohol content. We first apply our results…
We propose novel methodology for testing equality of model parameters between two high-dimensional populations. The technique is very general and applicable to a wide range of models. The method is based on sample splitting: the data is…
We propose a new, efficient multi-scale method to decompose a map (or signal in general) into components maps that contain structures of different sizes. In the widely-used wave transform, artifacts containing negative values arise around…
The multivariate hypergeometric distribution describes sampling without replacement from a discrete population of elements divided into multiple categories. Addressing a gap in the literature, we tackle the challenge of estimating discrete…
Mathematical methods of step-by-step and combined shifts are proposed for experimental data processing to reconstruct the measuring system impulse response distorted by shift-invariant blur. Proposed methods base on direct non-blind…
In this paper we study the problem of density deconvolution under general assumptions on the measurement error distribution. Typically deconvolution estimators are constructed using Fourier transform techniques, and it is assumed that the…