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Related papers: Cellular Adaptation Accounts for the Sparse and Re…

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The nervous system represents time-dependent signals in sequences of discrete action potentials or spikes, all spikes are identical so that information is carried only in the spike arrival times. We show how to quantify this information, in…

Condensed Matter · Physics 2008-02-03 S. P. Strong , Roland Koberle , Rob R. de Ruyter van Steveninck , William Bialek

Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

Neurons and Cognition · Quantitative Biology 2022-08-15 Ganchao Wei , Ian H. Stevenson

Animals move smoothly and reliably in unpredictable environments. Models of sensorimotor control have assumed that sensory information from the environment leads to actions, which then act back on the environment, creating a single,…

Neurons and Cognition · Quantitative Biology 2023-01-11 Jing Shuang Li , Anish A. Sarma , Terrence J. Sejnowski , John C. Doyle

Adaptive reasoning enables humans to flexibly adjust inference strategies when environmental rules or contexts change, yet its underlying neural dynamics remain unclear. This study investigated the neurophysiological mechanisms of adaptive…

Artificial Intelligence · Computer Science 2025-11-12 Jun-Young Kim , Young-Seok Kweon , Gi-Hwan Shin , Seong-Whan Lee

The effects of spike timing precision and dynamical behavior on error correction in spiking neurons were investigated. Stationary discharges -- phase locked, quasiperiodic, or chaotic -- were induced in a simulated neuron by presenting…

Neurons and Cognition · Quantitative Biology 2007-05-23 Michael Stiber

While the sparse coding principle can successfully model information processing in sensory neural systems, it remains unclear how learning can be accomplished under neural architectural constraints. Feasible learning rules must rely solely…

Machine Learning · Computer Science 2017-05-23 Tsung-Han Lin

To make informed decisions in natural environments that change over time, humans must update their beliefs as new observations are gathered. Studies exploring human inference as a dynamical process that unfolds in time have focused on…

Neurons and Cognition · Quantitative Biology 2022-03-03 Arthur Prat-Carrabin , Robert C. Wilson , Jonathan D. Cohen , Rava Azeredo da Silveira

Sensory processing is hard because the variables of interest are encoded in spike trains in a relatively complex way. A major goal in sensory processing is to understand how the brain extracts those variables. Here we revisit a common…

Neurons and Cognition · Quantitative Biology 2017-09-06 Sina Tootoonian , Peter Latham

Short-term changes in efficacy have been postulated to enhance the ability of synapses to transmit information between neurons, and within neuronal networks. Even at the level of connections between single neurons, direct confirmation of…

Neurons and Cognition · Quantitative Biology 2012-04-30 Pat Scott , Anna I. Cowan , Christian Stricker

A central question in neuroscience is to understand how noisy firing patterns are used to transmit information. Because neural spiking is noisy, spiking patterns are often quantified via pairwise correlations, or the probability that two…

Neurons and Cognition · Quantitative Biology 2017-05-29 Andrea K. Barreiro , Cheng Ly

Sensory perception originates from the responses of sensory neurons, which react to a collection of sensory signals linked to various physical attributes of a singular perceptual object. Unraveling how the brain extracts perceptual…

Neurons and Cognition · Quantitative Biology 2025-10-27 Zhichao Zhu , Yang Qi , Wenlian Lu , Jianfeng Feng

Sensory stimuli can be recognized more rapidly when they are expected. This phenomenon depends on expectation affecting the cortical processing of sensory information. However, virtually nothing is known on the mechanisms responsible for…

Neurons and Cognition · Quantitative Biology 2018-11-05 Luca Mazzucato , Giancarlo La Camera , Alfredo Fontanini

Simultaneous behavioral and electrophysiological recordings call for new methods to reveal the interactions between neural activity and behavior. A milestone would be an interpretable model of the co-variability of spiking activity and…

Neurons and Cognition · Quantitative Biology 2023-12-04 Christos Sourmpis , Carl Petersen , Wulfram Gerstner , Guillaume Bellec

Continuous adaptation allows survival in an ever-changing world. Adjustments in the synaptic coupling strength between neurons are essential for this capability, setting us apart from simpler, hard-wired organisms. How these changes can be…

Neurons and Cognition · Quantitative Biology 2021-01-06 Jakob Jordan , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici

Sensory adaptation enables organisms to adjust their perception in a changing environment. A paradigm is bacterial chemotaxis, where the output activity of chemoreceptors is adapted to different baseline concentrations via receptor…

Cell Behavior · Quantitative Biology 2024-01-23 Vansh Kharbanda , Benedikt Sabass

In this correspondence information theoretical tools are used to investigate the statistical properties of modeled cochlear nucleus globular bushy cell spike trains. The firing patterns are obtained from a simulation software that generates…

Neurons and Cognition · Quantitative Biology 2012-04-25 Andrea Grigorescu , Marek Rudnicki , Michael Isik , Werner Hemmert , Stefano Rini

It was observed before that due to convergence in the olfactory system a possible amplification can be as large as the degree of convergence. This is in the case when a single impulse from the converging inputs is enough to trigger the…

Neurons and Cognition · Quantitative Biology 2019-01-28 Alexander Vidybida

A quantitative understanding of how sensory signals are transformed into motor outputs places useful constraints on brain function and helps reveal the brain's underlying computations. We investigate how the nematode C. elegans responds to…

Neurons and Cognition · Quantitative Biology 2020-08-18 Mochi Liu , Anuj K Sharma , Joshua W Shaevitz , Andrew M Leifer

The hippocampus is often attributed to episodic memory formation and storage in the mammalian brain; in particular, Alme et al. showed that hippocampal area CA3 forms statistically independent representations across a large number of…

Neurons and Cognition · Quantitative Biology 2021-01-01 Bhav Jain , Sean Elliott

Biological systems display impressive capabilities in effectively responding to environmental signals in real time. There is increasing evidence that organisms may indeed be employing near optimal Bayesian calculations in their…

Neurons and Cognition · Quantitative Biology 2010-02-12 Steve Yaeli , Ron Meir