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Magnetic Resonance Spectroscopic Imaging (MRSI) is a non-invasive imaging technique for studying metabolism and has become a crucial tool for understanding neurological diseases, cancers and diabetes. High spatial resolution MRSI is needed…

Diffusion-weighted MRI (DW-MRI) is used to quantitatively characterize the microscopic structure of soft tissue due to the anisotropic diffusion of water in muscle. Applications such as fiber tractography or modeling of tumor spread in soft…

Medical Physics · Physics 2024-06-07 Nadya Shusharina , Xiaofeng Liu , Evangelia Kaza , Miranda Lam , Stephan Maier , Jonghye Woo

Having a material that is matched in acoustic impedance with the surrounding medium is a considerable asset for many underwater acoustic applications. In this work, impedance matching is achieved by dispersing small, deeply subwavelength…

Applied Physics · Physics 2018-06-01 Reine-Marie Guillermic , Maxime Lanoy , Anatoliy Strybulevych , John H. Page

Self-assembling peptides (SAPs) have shown to offer great promise in therapeutics and have the ability to undergo self-assembly and form ordered nanostructures. However SAP gels are often associated with inherent weak and transient…

Nuclear Magnetic Resonance (NMR) is one of the most powerful experimental techniques to characterize the structure of molecules and confined liquids. Nevertheless, the complexity of the systems under investigation usually requires…

We present a new method for introducing stable non-equilibrium concentration gradients in molecular dynamics simulations of mixtures. This method extends earlier Reverse Non-Equilibrium Molecular Dynamics (RNEMD) methods which use kinetic…

Chemical Physics · Physics 2024-08-06 Cody R. Drisko , J. Daniel Gezelter

We study the mass spectrum of sub-structures in the Perseus Molecular Cloud Complex traced by 13CO (1-0), finding that $dN/dM\propto M^{-2.4}$ for the standard Clumpfind parameters. This result does not agree with the classical…

Astrophysics of Galaxies · Physics 2009-07-22 Jaime E. Pineda , Erik W. Rosolowsky , Alyssa A. Goodman

We have implemented and tested the method we have recently proposed [J. Phys. Chem. Lett. 10, 1537 (2019)] to treat dispersion interactions, which is derived from a supramolecular wavefunction constrained to leave the diagonal of the…

Chemical Physics · Physics 2020-07-01 Derk P. Kooi , Timo Weckman , Paola Gori-Giorgi

We have developed a poly(dimethylsiloxane) (PDMS) microfluidic chip to study the directional drying of a colloidal dispersion confined in a channel. Our measurements on a dispersion of silica nanoparticles once again revealed the…

Soft Condensed Matter · Physics 2024-01-11 Hrishikesh Pingulkar , Sonia Maréchal , Jean-Baptiste Salmon

We present a dual-resolution molecular dynamics (MD) simulation of liquid water employing a recently introduced Adaptive Resolution Scheme (AdResS). The spatially adaptive molecular resolution procedure allows for changing from a…

Soft Condensed Matter · Physics 2011-11-10 Silvina Matysiak , Cecilia Clementi , Matej Praprotnik , Kurt Kremer , Luigi Delle Site

Phosphorylation is one of the most important protein modifications, and electron-transfer dissociation tandem mass spectrometry (ETD-MS/MS) is a potentially useful method for the sequencing of phosphopeptides, including determination of the…

Chemical Physics · Physics 2018-11-27 Daiki Asakawa , Akio Miyazato , Frederic Rosu , Valérie Gabelica

Diffusion coefficient measurements are important for many biological and material investigations, such as particle dynamics, kinetics, and size determinations. Amongst current measurement methods, single particle tracking (SPT) offers the…

Biomolecules · Quantitative Biology 2011-07-12 Shannon Kian Zareh , Michael C. DeSantis , Jonathan Kessler , Je-Luen Li , Y. M. Wang

The effect of the applied trajectory length on the convergence of the static dielectric constant and the self-diffusion coefficient were examined for the SPC/E water model in the NVT ensemble with different system size at 293 K. Very long…

Disordered Systems and Neural Networks · Physics 2015-05-20 Orsolya Gereben , Laszlo Pusztai

Realistic nuclear level densities (NLDs) obtained within the spectral distribution method (SDM) are employed to study nuclear processes of astrophysical interest. The merit of SDM lies in the fact that the NLDs corresponding to many body…

Nuclear Theory · Physics 2022-05-04 Sangeeta , T. Ghosh , B. Maheshwari , G. Saxena , B. K. Agrawal

The symmetrized Density-Matrix-Renormalization-Group (DMRG) method is used to study linear and nonlinear optical properties of Free base porphine and metallo-porphine. Long-range interacting model, namely, Pariser-Parr-Pople (PPP) model is…

Mesoscale and Nanoscale Physics · Physics 2015-05-30 Manoranjan Kumar , Y. Anusooya Pati , S. Ramasesha

Diffusing alpha-emitters radiation therapy (Alpha-DaRT) is a new modality that uses alpha particles to treat solid tumors. Alpha-DaRT employs interstitial sources loaded with low activities of Radium-224, which release a chain of…

We demonstrate the densification of a granular model system of polystyrene spheres over time by shaking with varying excitation amplitudes or effective temperatures. This densification is quantified by the mean square displacement (MSD),…

Soft Condensed Matter · Physics 2025-08-05 Marlo Kunzner , Christopher Mayo , Matthias Sperl , Jan Philipp Gabriel

We examine by extensive computer simulations the self-diffusion of anisotropic star like particles in crowded two-dimensional solutions. We investigate the implications of the area coverage fraction $\phi$ of the crowders and the…

Soft Condensed Matter · Physics 2016-09-26 Jaeoh Shin , Andrey G. Cherstvy , Ralf Metzler

We reveal an unreported physical mechanism that enables the pre-concentration, sorting and characterization of charged polystyrene nanobeads and liposomes dispersed in a continuous flow within a straight micron-sized channel. Initially, a…

Thermoresponsive hydrogels have been studied intensively for creating smart drug carriers and controlled drug delivery. Understanding the drug release kinetics and corresponding transport mechanisms of nanoparticles (NPs) in a…

Soft Condensed Matter · Physics 2020-05-12 Yi Wang , Zhen Li , Jie Ouyang , George Em Karniadakis