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Information flow provides a natural measure for the causal interaction between dynamical events. This study extends our previous rigorous formalism of componentwise information flow to the bulk information flow between two complex…

Neurons and Cognition · Quantitative Biology 2021-12-30 X. San Liang

Living systems are often described utilizing informational analogies. An important open question is whether information is merely a useful conceptual metaphor, or intrinsic to the operation of biological systems. To address this question,…

Molecular Networks · Quantitative Biology 2015-08-19 Hyunju Kim , Paul Davies , Sara Imari Walker

A central challenge in analyzing multivariate interactions within complex systems is to decompose how multiple inputs jointly determine an output. Existing approaches generally operate on observed probability distributions and can conflate…

Information Theory · Computer Science 2026-03-19 Clifford Bohm , Vincent R. Ragusa , Arend Hintze , Charles Ofria , Emily Dolson , Christoph Adami

Empirical evidence suggesting that living systems might operate in the vicinity of critical points, at the borderline between order and disorder, has proliferated in recent years, with examples ranging from spontaneous brain activity to…

Statistical Mechanics · Physics 2014-07-25 Jorge Hidalgo , Jacopo Grilli , Samir Suweis , Miguel A. Munoz , Jayanth R. Banavar , Amos Maritan

Communication of information in complex systems can be considered as major driver of systems evolution. What matters is not the communicated information by itself but rather the meaning that is supplied to the information. However…

Computers and Society · Computer Science 2023-04-28 Inga Ivanova

Multivariate information decompositions hold promise to yield insight into complex systems, and stand out for their ability to identify synergistic phenomena. However, the adoption of these approaches has been hindered by there being…

Information Theory · Computer Science 2020-12-02 Fernando Rosas , Pedro Mediano , Borzoo Rassouli , Adam Barrett

Since the discovery of the presence of biogenic magnetites in living organisms, there have been speculations on the role that these biomagnetites play in cellular processes. It seems that the formation of biomagnetite crystals is a…

Biological Physics · Physics 2010-12-16 Istvan Bokkon , Vahid Salari

Living entities in a group communicate and transfer information to one another for a variety of reasons. It might be for foraging food, migration, or escaping threats and obstacles, etc. They do so by interacting with each other and also…

Biological Physics · Physics 2024-04-03 Md. Samsuzzaman , Mohammad Hasanuzzaman , Ahmed Sayeed , Arnab Saha

Understanding functional organization of genetic information is a major challenge in modern biology. Following the initial publication of the human genome sequence in 2001, advances in high-throughput measurement technologies and efficient…

Machine Learning · Statistics 2011-03-01 Leo Lahti

An outstanding problem in neuroscience is to understand how information is integrated across the many modules of the brain. While classic information-theoretic measures have transformed our understanding of feedforward information…

Neurons and Cognition · Quantitative Biology 2019-02-12 Daniel Toker , Friedrich T. Sommer

Fundamental approaches bypass the problem of getting consciousness from non-conscious components by positing that consciousness is a universal primitive. For example, the double aspect theory of information holds that information has a…

adap-org · Physics 2007-05-23 L. Gabora

Through in-depth thinking and reasoning about the conditions required for cells to maintain unchanged material distribution, it is concluded that life metabolic reactions require high information content. However, the self-replication of a…

Biological Physics · Physics 2024-08-27 Cheng Bi

Molecular data systems have the potential to store information at dramatically higher density than existing electronic media. Some of the first experimental demonstrations of this idea have used DNA, but nature also uses a wide diversity of…

Many biological phenomena or social events critically depend on how information evolves in complex networks. However, a general theory to characterize information evolution is yet absent. Consequently, numerous unknowns remain about the…

Biological Physics · Physics 2022-07-20 Yang Tian , Guoqi Li , Pei Sun

Quantum physics is a linear theory, so it is somewhat puzzling that it can underlie very complex systems such as digital computers and life. This paper investigates how this is possible. Physically, such complex systems are necessarily…

Quantum Physics · Physics 2024-03-12 George F R Ellis

Learning underlies nearly all human behavior and is central to education and education reform. Although recent advances in neuroscience have revealed the fundamental structure of learning processes, these insights have yet to be integrated…

Information Theory · Computer Science 2025-10-20 Scott E. Allen , A. David Redish , René F. Kizilcec

Despite recent molecular technique improvements, biological knowledge remains incomplete. Reasoning on living systems hence implies to integrate heterogeneous and partial informations. Although current investigations successfully focus on…

Quantitative Methods · Quantitative Biology 2009-09-29 Jérémie Bourdon , Damien Eveillard , Samuel Gabillard , Theo Merle

Over the past decade, machine learning has revolutionized computers' ability to analyze text through flexible computational models. Due to their structural similarity to written language, transformer-based architectures have also shown…

We report a realization of an associative memory signal/information processing system based on simple enzyme-catalyzed biochemical reactions. Optically detected chemical output is always obtained in response to the triggering input, but the…

Molecular Networks · Quantitative Biology 2013-04-23 Vera Bocharova , Kevin MacVittie , Soujanya Chinnapareddy , Jan Halamek , Vladimir Privman , Evgeny Katz

Models of the mind are based on the possibility of computing in brain microtubules. From this point of view, information processing is the fundamental issue for understanding the brain mechanisms that produce consciousness. The cytoskeleton…

Subcellular Processes · Quantitative Biology 2007-05-23 Jean Faber , Renato Portugal , Luiz Pinguelli Rosa