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From multicellular tissues to bacterial colonies, three dimensional cellular structures arise through the interaction of cellular activities and mechanical forces. Simple bacterial communities provide model systems for analyzing such…

Soft Condensed Matter · Physics 2024-01-11 Ana Carpio , Elena Cebrian , David R. Espeso , Perfecto Vidal

Biofilms are bacterial aggregates encased in a self-produced polymeric matrix which attach to moist surfaces and are extremely resistant to chemicals and antibiotics. Recent experiments show that their structure is defined by the interplay…

Soft Condensed Matter · Physics 2024-01-17 Ana Carpio , Elena Cebrian , Perfecto Vidal

Biofilms are ubiquitous macro-colonies of bacteria that develop at various interfaces (solid-liquid, solid-gas or liquid-gas). The formation of biofilms starts with the attachment of individual bacteria to an interface, where they…

Biological Physics · Physics 2016-11-03 Sarah Trinschek , Karin John , Uwe Thiele

The formation of bacterial biofilms on solid surfaces within a fluid starts when bacteria attach to the substrate. Understanding environmental factors affecting the attachment and the early stages of the biofilm development as well as the…

Applied Physics · Physics 2019-10-30 Sung-Ha Hong , Jean-Baptiste Gorce , Horst Punzmann , Nicolas Francois , Michael Shats , Hua Xia

Biofilms are antibiotic-resistant bacterial aggregates that grow on moist surfaces and can trigger hospital-acquired infections. They provide a classical example in biology where the dynamics of cellular communities may be observed and…

Biological Physics · Physics 2015-02-24 D. R. Espeso , A. Carpio , B. Einarsson

Formation of bacterial colonies as biofilm on the surface/interface of various objects has the potential to impact not only human health and disease but also energy and environmental considerations. Biofilms can be regarded as soft…

Fluid Dynamics · Physics 2015-09-15 Pallab Barai , Aloke Kumar , Partha P. Mukherjee

A stochastic model is used to assess the effect of external parameters on the development of submerged biofilms on smooth and rough surfaces. The model includes basic cellular mechanisms, such as division and spreading, together with an…

Soft Condensed Matter · Physics 2024-01-17 David Rodriguez , Baldvin Einarsson , Ana Carpio

Bacterial communities such as biofilms are widely recognised as being important for survival and persistence of bacteria in harsh environments. Mechanistic models of biofilm growth indicate that the way in which the surface is seeded can…

Quantitative Methods · Quantitative Biology 2007-05-23 Leah R. Johnson

Controlling bacterial surface adhesion and subsequent biofilm formation in fluid systems is crucial for the safety and efficacy of medical and industrial processes. Here, we theoretically examine the transport of bacteria close to surfaces,…

Soft Condensed Matter · Physics 2025-07-08 Edwina F. Yeo , Benjamin J. Walker , Philip Pearce , Mohit P. Dalwadi

Collective behavior of bacterial colonies plays critical roles in adaptability, survivability, biofilm expansion and infection. We employ an individual-based model of an interstitial biofilm to study emergent pattern formation based on the…

Adaptation and Self-Organizing Systems · Physics 2017-02-01 Cameron Zachreson , Christian Wolff , Cynthia B. Whitchurch , Milos Toth

Bacterial attachment to a fluid interface can lead to the formation of a film with physicochemical properties that evolve with time. We study the time evolution of interface (micro)mechanics for interfaces between oil and bacterial…

Soft Condensed Matter · Physics 2015-03-26 Liana Vaccari , Daniel Allan , Nima Sharifi-Mood , Aayush Singh , Robert Leheny , Kathleen Stebe

Bacterial biofilms collectively develop distinct and ordered structures, including fibers, bundles, and branches. Often, it is unclear how these structural motifs convey specific advantages to bacterial strains under challenging conditions.…

Soft Condensed Matter · Physics 2022-11-16 Mustafa Basaran , Tevfik Can Yüce , Yusuf Ilker Yaman , Roman Vetter , Askin Kocabas

The ability of bacteria to colonize and grow on different surfaces is an essential process for biofilm development and depends on complex biomechanical interactions between the biofilm and the underlying substrate. Changes in the physical…

Biological Physics · Physics 2021-03-16 Merrill Asp , Minh Tri Ho Thanh , Arvind Gopinath , Alison E. Patteson

Many organisms form colonies for a transient period of time to withstand environmental pressure. Bacterial biofilms are a prototypical example of such behavior. Despite significant interest across disciplines, physical mechanisms governing…

Soft Condensed Matter · Physics 2015-09-30 Christoph Weber , Yen Ting Lin , Nicolas Biais , Vasily Zaburdaev

Bacteria invade surfaces by forming dense colonies encased in a polymer matrix. Successful settlement of founder bacteria, early microcolony development and later macroscopic spreading of these biofilms on surfaces rely on complex physical…

Soft Condensed Matter · Physics 2025-08-27 Anthony Pietz , Karin John , Uwe Thiele

The bacterium {\em Bacilus subtilis} frequently forms biofilms at the interface between the culture medium and the air. We develop a mathematical model that couples a description of bacteria as individual discrete objects to the standard…

Cell Behavior · Quantitative Biology 2015-12-16 Maxime Ardré , Hervé Henry , Carine Douarche , Mathis Plapp

We introduce and analyze a model for osmotically spreading biofilm colonies at solid-air interfaces that includes wetting phenomena, i.e. surface forces. The model combines a hydrodynamic description for biologically passive liquid…

Biological Physics · Physics 2017-08-23 Sarah Trinschek , Karin John , Sigolène Lecuyer , Uwe Thiele

Biofilms are communities of bacteria that exhibit a multitude of multiscale biomechanical behaviors. Recent experimental advances have lead to characterizations of these behaviors in terms of measurements of the viscoelastic moduli of…

Cell Behavior · Quantitative Biology 2017-07-19 Jay A. Stotsky , Vanja Dukic , David M. Bortz

The classical problem of foam film rupture dynamics has been investigated when surfaces exhibit very high rigidity due to the presence of specific surfactants. Two new features are reported. First a strong deviation to the well-known…

Soft Condensed Matter · Physics 2023-07-19 Pauline Petit , Marie Le Merrer , Anne-Laure Biance

Biofilms are complex, self-organized consortia of microorganisms that produce a functional, protective matrix of biomolecules. Physically, the structure of a biofilm can be described as an entangled polymer network which grows and changes…

Biological Physics · Physics 2016-11-08 Marco G. Mazza
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