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Related papers: Graphical Modelling in Genetics and Systems Biolog…

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Graphs as a type of data structure have recently attracted significant attention. Representation learning of geometric graphs has achieved great success in many fields including molecular, social, and financial networks. It is natural to…

Machine Learning · Computer Science 2021-07-08 Tian Xia , Wei-Shinn Ku

In this manuscript we review new ideas and first results on application of the Graphical Models approach, originated from Statistical Physics, Information Theory, Computer Science and Machine Learning, to optimization problems of network…

Systems and Control · Computer Science 2017-02-08 Michael Chertkov , Sidhant Misra , Marc Vuffray , Dvijotham Krishnamurty , Pascal Van Hentenryck

Traffic forecasting is important for the success of intelligent transportation systems. Deep learning models, including convolution neural networks and recurrent neural networks, have been extensively applied in traffic forecasting problems…

Machine Learning · Computer Science 2022-07-08 Weiwei Jiang , Jiayun Luo

A graphical model is an undirected network representing the conditional independence properties between random variables. Graphical modeling has become part and parcel of systems or network approaches to multivariate data, in particular…

Methodology · Statistics 2024-08-20 Carel F. W. Peeters , Anders Ellern Bilgrau , Wessel N. van Wieringen

Graph Machine Learning (GML) is receiving growing interest within the pharmaceutical and biotechnology industries for its ability to model biomolecular structures, the functional relationships between them, and integrate multi-omic datasets…

Modern energy systems in vehicles and built infrastructure are governed by high-dimensional dynamics spanning multiple physical domains (e.g., electrical, thermal, mechanical) and timescales. This tutorial paper presents a graph-based…

Graphs are widespread data structures used to model a wide variety of problems. The sheer amount of data to be processed has prompted the creation of a myriad of systems that help us cope with massive scale graphs. The pressure to deliver…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-10-09 Luis M. Vaquero , Felix Cuadrado , Matei Ripeanu

A recent trend in the context of graph theory is to bring theoretical analyses closer to empirical observations, by focusing the studies on random graph models that are used to represent practical instances. There, it was observed that…

Discrete Mathematics · Computer Science 2024-07-11 Tobias Friedrich , Andreas Göbel , Maximilian Katzmann , Leon Schiller

Over the past decade, advances in generative modeling, such as generative adversarial networks, masked autoencoders, and diffusion models, have significantly transformed biological research and discovery, enabling breakthroughs in molecule…

Machine Learning · Computer Science 2026-03-10 Zihao Li , Zhichen Zeng , Xiao Lin , Feihao Fang , Yanru Qu , Zhe Xu , Zhining Liu , Xuying Ning , Tianxin Wei , Ge Liu , Hanghang Tong , Jingrui He

Graphs are commonly used to characterise interactions between objects of interest. Because they are based on a straightforward formalism, they are used in many scientific fields from computer science to historical sciences. In this paper,…

Machine Learning · Statistics 2015-06-24 Pierre Latouche , Fabrice Rossi

Many current challenges involve understanding the complex dynamical interplay between the constituents of systems. Typically, the number of such constituents is high, but only limited data sources on them are available. Conventional…

Populations and Evolution · Quantitative Biology 2021-12-17 Jana C. Massing , Thilo Gross

Multivariate statistical analysis is concerned with observations on several variables which are thought to possess some degree of inter-dependence. Driven by problems in genetics and the social sciences, it first flowered in the earlier…

Statistics Theory · Mathematics 2007-06-13 Iain M. Johnstone

Graph learning methods have recently been receiving increasing interest as means to infer structure in datasets. Most of the recent approaches focus on different relationships between a graph and data sample distributions, mostly in…

Machine Learning · Computer Science 2020-03-23 Hermina Petric Maretic , Pascal Frossard

Mathematical modelling has a long history in the context of collective cell migration, with applications throughout development, disease and regenerative medicine. The aim of modelling in this context is to provide a framework in which to…

Quantitative Methods · Quantitative Biology 2025-06-24 Ruth E. Baker , Rebecca M. Crossley , Carles Falco , Simon F. Martina-Perez

Graphs are common mathematical structures that are visual and intuitive. They constitute a natural and seamless way for system modelling in science, engineering and beyond, including computer science, biology, business process modelling,…

Formal Languages and Automata Theory · Computer Science 2020-12-03 Berthold Hoffmann , Mark Minas

Cell fate decisions emerge as a consequence of a complex set of gene regulatory networks. Models of these networks are known to have more parameters than data can determine. Recent work, inspired by Waddington's metaphor of a landscape, has…

Quantitative Methods · Quantitative Biology 2023-05-08 Archishman Raju , Eric D. Siggia

Statistical mechanics is one of the most powerful and elegant tools in the quantitative sciences. One key virtue of statistical mechanics is that it is designed to examine large systems with many interacting degrees of freedom, providing a…

Quantitative Methods · Quantitative Biology 2007-08-15 Hernan G. Garcia , Jané Kondev , Nigel Orme , Julie A. Theriot , Rob Phillips

Discovering causal genetic variants from large genetic association studies poses many difficult challenges. Assessing which genetic markers are involved in determining trait status is a computationally demanding task, especially in the…

Genomics · Quantitative Biology 2015-04-09 Andrew L. Beam , Alison Motsinger-Reif , Jon Doyle

Graphs are a powerful tool for representing and analyzing unstructured, non-Euclidean data ubiquitous in the healthcare domain. Two prominent examples are molecule property prediction and brain connectome analysis. Importantly, recent works…

Machine Learning · Computer Science 2022-04-04 Kamilia Mullakaeva , Luca Cosmo , Anees Kazi , Seyed-Ahmad Ahmadi , Nassir Navab , Michael M. Bronstein

Generative models based on diffusion have become the state of the art in the last few years, notably for image generation. Here, we analyse them in the high-dimensional limit, where data are formed by a very large number of variables. We…

Disordered Systems and Neural Networks · Physics 2023-10-31 Giulio Biroli , Marc Mézard