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Bio image analysis has recently become one keystone of biological research but biologists tend to get lost in a plethora of available software and the way to adjust available tools to their own image analysis problem. We present BIII,…

Mapping human genetic variation is fundamentally interesting in fields such as anthropology and forensic inference. At the same time patterns of genetic diversity confound efforts to determine the genetic basis of complex disease. Due to…

Applications · Statistics 2010-07-13 Ann B. Lee , Diana Luca , Kathryn Roeder

The emergence of large spectroscopic surveys requires homogenising on the same scale the quantities they measure in order to increase their scientific legacy. We developed the SpectroTranslator, a data-driven deep neural network algorithm…

J-PET Framework is an open-source software platform for data analysis, written in C++ and based on the ROOT package. It provides a common environment for implementation of reconstruction, calibration and filtering procedures, as well as for…

Instrumentation and Detectors · Physics 2020-05-28 Wojciech Krzemien , Aleksander Gajos , Krzysztof Kacprzak , Kamil Rakoczy , Grzegorz Korcyl

DNA-interacting proteins have roles multiple processes, many operating as molecular machines which undergo dynamic metastable transitions to bring about their biological function. To fully understand this molecular heterogeneity, DNA and…

Biomolecules · Quantitative Biology 2015-04-15 Adam J. M. Wollman , Helen Miller , Zhaokun Zhou , Mark C. Leake

Mass spectrometry (MS) based single-cell proteomics (SCP) explores cellular heterogeneity by focusing on the functional effectors of the cells - proteins. However, extracting meaningful biological information from MS data is far from…

PanGeneHome is a web server dedicated to the analysis of available microbial pangenomes. For any prokaryotic taxon with at least three sequenced genomes, PanGeneHome provides (i) conservation level of genes, (ii) pangenome and core-genome…

The Intelligent Fault Diagnosis of rotating machinery currently proposes some captivating challenges. Although results achieved by artificial intelligence and deep learning constantly improve, this field is characterized by several open…

Signal Processing · Electrical Eng. & Systems 2022-07-26 Eugenio Brusa , Cristiana Delprete , Luigi Gianpio Di Maggio

Optunity is a free software package dedicated to hyperparameter optimization. It contains various types of solvers, ranging from undirected methods to direct search, particle swarm and evolutionary optimization. The design focuses on ease…

Machine Learning · Computer Science 2014-12-04 Marc Claesen , Jaak Simm , Dusan Popovic , Yves Moreau , Bart De Moor

Motivation: Quality control of genomic data is an essential but complicated multi-step procedure, often requiring separate installation and expert familiarity with a combination of disparate bioinformatics tools. Results: To provide an…

Genomics · Quantitative Biology 2021-05-06 Christina Vasilopoulou , Benjamin Wingfield , Andrew P. Morris , William Duddy

Binary Code Similarity Detection (BCSD) is not only essential for security tasks such as vulnerability identification but also for code copying detection, yet it remains challenging due to binary stripping and diverse compilation…

Cryptography and Security · Computer Science 2025-04-24 Li Zhou , Marc Dacier , Charalambos Konstantinou

The analysis of experimental results with Python often requires writing many code scripts which all need access to the same set of functions. In a common field of research, this set will be nearly the same for many users. The qspec Python…

Computational Physics · Physics 2025-03-18 Patrick Müller , Wilfried Nörtershäuser

Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational relief. Comparing genomic sequences is one of the most…

Unambiguously identifying molecules in spectra is of fundamental importance for a variety of scientific and industrial uses. Interpreting atmospheric spectra for the remote detection of volatile compounds requires information about the…

Chemical Physics · Physics 2019-11-12 Clara Sousa-Silva , Janusz J Petkowski , Sara Seager

Analyzing a functional genomics experiment, such as ATAC-, ChIP- or RNA-sequencing, requires reference data including a genome assembly and gene annotation. These resources can generally be retrieved from different organizations and in…

Genomics · Quantitative Biology 2022-09-05 Siebren Frölich , Maarten van der Sande , Tilman Schäfers , Simon J. van Heeringen

Computational tools for normal mode analysis, which are widely used in physics and materials science problems, are designed here in a single package called NMscatt (Normal Modes & scattering) that allows arbitrarily large systems to be…

Computational Physics · Physics 2009-11-13 Franci Merzel , Fabien Fontaine-Vive , Mark R. Johnson

Common Spacial Patterns (CSP) is a widely used method to analyse electroencephalography (EEG) data, concerning the supervised classification of brain's activity. More generally, it can be useful to distinguish between multivariate signals…

Mathematical Software · Computer Science 2021-09-07 Itsaso Rodriguez , Itziar Irigoien , Basilio Sierra , Concepcion Arenas

Raman spectroscopy is a well established tool for the analysis of vibration spectra, which then allow for the determination of individual substances in a chemical sample, or for their phase transitions. In the…

Numerical Analysis · Mathematics 2020-07-15 Konstantin Fackeldey , Jonas Röhm , Amir Niknejad , Surahit Chewle , Marcus Weber

Mathematical modelling allows us to concisely describe fundamental principles in biology. Analysis of models can help to both explain known phenomena, and predict the existence of new, unseen behaviours. Model analysis is often a complex…

Quantitative Methods · Quantitative Biology 2020-08-13 Mark Blyth , Ludovic Renson , Lucia Marucci

Spectroscopy is an important tool for probing the properties of materials, chemicals and biological samples. We design a practical transmitter-receiver system that exploits entanglement to achieve a provable quantum advantage over all…

Quantum Physics · Physics 2020-11-03 Haowei Shi , Zheshen Zhang , Stefano Pirandola , Quntao Zhuang
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