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Clustering algorithms are one of the main analytical methods to detect patterns in unlabeled data. Existing clustering methods typically treat samples in a dataset as points in a metric space and compute distances to group together similar…

Machine Learning · Computer Science 2021-10-12 Tarek Naous , Srinjay Sarkar , Abubakar Abid , James Zou

The mixture model is undoubtedly one of the greatest contributions to clustering. For continuous data, Gaussian models are often used and the Expectation-Maximization (EM) algorithm is particularly suitable for estimating parameters from…

Machine Learning · Statistics 2025-11-25 Zineddine Tighidet , Lazhar Labiod , Mohamed Nadif

Active learning selects the most informative samples from the unlabelled dataset to annotate in the context of a limited annotation budget. While numerous methods have been proposed for subsequent sample selection based on an initialized…

Machine Learning · Computer Science 2024-03-28 Han Yuan , Chuan Hong

This paper addresses the problem of unsupervised clustering which remains one of the most fundamental challenges in machine learning and artificial intelligence. We propose the clustered generator model for clustering which contains both…

Machine Learning · Statistics 2019-11-20 Dandan Zhu , Tian Han , Linqi Zhou , Xiaokang Yang , Ying Nian Wu

Model-based clustering is widely-used in a variety of application areas. However, fundamental concerns remain about robustness. In particular, results can be sensitive to the choice of kernel representing the within-cluster data density.…

Machine Learning · Statistics 2019-06-27 Leo L Duan , David B Dunson

In this article, we investigate the use of a probabilistic model for unsupervised clustering in text collections. Unsupervised clustering has become a basic module for many intelligent text processing applications, such as information…

Information Retrieval · Computer Science 2016-08-16 Loïs Rigouste , Olivier Cappé , François Yvon

Bi-clustering is a useful approach in analyzing biological data when observations come from heterogeneous groups and have a large number of features. We outline a general Bayesian approach in tackling bi-clustering problems in moderate to…

Applications · Statistics 2021-02-11 Han Yan , Jiexing Wu , Yang Li , Jun S. Liu

Rapid technological advances have allowed for molecular profiling across multiple omics domains from a single sample for clinical decision making in many diseases, especially cancer. As tumor development and progression are dynamic…

Methodology · Statistics 2022-02-11 Dongyan Yan , Subharup Guha

Biclustering is used for simultaneous clustering of the observations and variables when there is no group structure known \textit{a priori}. It is being increasingly used in bioinformatics, text analytics, etc. Previously, biclustering has…

Methodology · Statistics 2020-09-14 Wangshu Tu , Sanjeena Subedi

Over the last decade, a large variety of clustering algorithms have been developed to detect coregulatory relationships among genes from microarray gene expression data. Model based clustering approaches have emerged as statistically well…

Quantitative Methods · Quantitative Biology 2008-01-15 Anagha Joshi , Yves Van de Peer , Tom Michoel

The problem of multimodal clustering arises whenever the data are gathered with several physically different sensors. Observations from different modalities are not necessarily aligned in the sense there there is no obvious way to associate…

Machine Learning · Statistics 2020-12-10 Vasil Khalidov , Florence Forbes , Radu Horaud

Network models provide a powerful framework for analysing single-cell count data, facilitating the characterisation of cellular identities, disease mechanisms, and developmental trajectories. However, uncertainty modeling in unsupervised…

Genomics · Quantitative Biology 2026-04-27 Shanshan Ren , Thomas E. Bartlett , Lina Gerontogianni , Swati Chandna

We discuss functional clustering procedures for nested designs, where multiple curves are collected for each subject in the study. We start by considering the application of standard functional clustering tools to this problem, which leads…

Applications · Statistics 2014-11-21 Abel Rodriguez , David B. Dunson

This paper studies a factor modeling-based approach for clustering high-dimensional data generated from a mixture of strongly correlated variables. Statistical modeling with correlated structures pervades modern applications in economics,…

Statistics Theory · Mathematics 2024-08-23 Shange Tang , Soham Jana , Jianqing Fan

We address the problem of data clustering by introducing an unsupervised, parameter free approach based on maximum likelihood principle. Starting from the observation that data sets belonging to the same cluster share a common information,…

Statistical Mechanics · Physics 2009-11-07 Lorenzo Giada , Matteo Marsili

Typical deep clustering methods, while achieving notable progress, can only provide one clustering result per dataset. This limitation arises from their assumption of a fixed underlying data distribution, which may fail to meet user needs…

Machine Learning · Computer Science 2025-12-02 Xinyue Wang , Yuheng Jia , Hui Liu , Junhui Hou

Identification of disease subtypes and corresponding biomarkers can substantially improve clinical diagnosis and treatment selection. Discovering these subtypes in noisy, high dimensional biomedical data is often impossible for humans and…

Quantitative Methods · Quantitative Biology 2020-05-18 Marc-Andre Schulz , Matt Chapman-Rounds , Manisha Verma , Danilo Bzdok , Konstantinos Georgatzis

Clustering is commonly performed as an initial analysis step for uncovering structure in 'omics datasets, e.g. to discover molecular subtypes of disease. The high-throughput, high-dimensional nature of these datasets means that they provide…

Methodology · Statistics 2023-03-02 Paul D. W. Kirk , Filippo Pagani , Sylvia Richardson

To identify novel dynamic patterns of gene expression, we develop a statistical method to cluster noisy measurements of gene expression collected from multiple replicates at multiple time points, with an unknown number of clusters. We…

Applications · Statistics 2013-12-02 Audrey Qiuyan Fu , Steven Russell , Sarah J. Bray , Simon Tavaré

Identification of the clusters from an unlabeled data set is one of the most important problems in Unsupervised Machine Learning. The state of the art clustering algorithms are based on either the statistical properties or the geometric…

Machine Learning · Computer Science 2018-01-04 Sambarta Dasgupta , Keivan Ebrahimi , Umesh Vaidya
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