English
Related papers

Related papers: Integrative Model-based clustering of microarray m…

200 papers

Model-based clustering is a popular approach for clustering multivariate data which has seen applications in numerous fields. Nowadays, high-dimensional data are more and more common and the model-based clustering approach has adapted to…

Methodology · Statistics 2018-09-25 Michael Fop , Thomas Brendan Murphy

Robust clustering from incomplete data is an important topic because, in many practical situations, real data sets are heavy-tailed, asymmetric, and/or have arbitrary patterns of missing observations. Flexible methods and algorithms for…

Methodology · Statistics 2018-11-13 Yuhong Wei , Yang Tang , Paul D. McNicholas

Through Ecological Momentary Assessment (EMA) studies, a number of time-series data is collected across multiple individuals, continuously monitoring various items of emotional behavior. Such complex data is commonly analyzed in an…

Machine Learning · Computer Science 2023-10-12 Mandani Ntekouli , Gerasimos Spanakis , Lourens Waldorp , Anne Roefs

High-dimensional data of discrete and skewed nature is commonly encountered in high-throughput sequencing studies. Analyzing the network itself or the interplay between genes in this type of data continues to present many challenges. As…

Methodology · Statistics 2017-12-01 Anjali Silva , Steven J. Rothstein , Paul D. McNicholas , Sanjeena Subedi

Clustering algorithms are pivotal in data analysis, enabling the organization of data into meaningful groups. However, individual clustering methods often exhibit inherent limitations and biases, preventing the development of a universal…

Neural and Evolutionary Computing · Computer Science 2024-12-13 H. Jahani , F. Zamio

In an age of increasingly large data sets, investigators in many different disciplines have turned to clustering as a tool for data analysis and exploration. Existing clustering methods, however, typically depend on several nontrivial…

Quantitative Methods · Quantitative Biology 2009-11-11 Noam Slonim , Gurinder Singh Atwal , Gasper Tkacik , William Bialek

The use of a finite mixture of normal distributions in model-based clustering allows to capture non-Gaussian data clusters. However, identifying the clusters from the normal components is challenging and in general either achieved by…

Methodology · Statistics 2016-06-21 Gertraud Malsiner-Walli , Sylvia Frühwirth-Schnatter , Bettina Grün

Clustering mixed data presents numerous challenges inherent to the very heterogeneous nature of the variables. A clustering algorithm should be able, despite of this heterogeneity, to extract discriminant pieces of information from the…

Machine Learning · Computer Science 2022-05-10 Robin Fuchs , Denys Pommeret , Cinzia Viroli

We propose a mixture of latent trait models with common slope parameters (MCLT) for model-based clustering of high-dimensional binary data, a data type for which few established methods exist. Recent work on clustering of binary data, based…

Methodology · Statistics 2017-10-09 Yang Tang , Ryan P. Browne , Paul D. McNicholas

Microarrays are made it possible to simultaneously monitor the expression profiles of thousands of genes under various experimental conditions. Identification of co-expressed genes and coherent patterns is the central goal in microarray or…

Computational Engineering, Finance, and Science · Computer Science 2012-01-25 T. Chandrasekhar , K. Thangavel , E. Elayaraja

In recent years, advances in high throughput sequencing technology have led to a need for specialized methods for the analysis of digital gene expression data. While gene expression data measured on a microarray take on continuous values…

Applications · Statistics 2012-02-29 Daniela M. Witten

In model-based clustering and classification, the cluster-weighted model constitutes a convenient approach when the random vector of interest constitutes a response variable Y and a set p of explanatory variables X. However, its…

Methodology · Statistics 2013-07-23 Sanjeena Subedi , Antonio Punzo , Salvatore Ingrassia , Paul D. McNicholas

Medical data often exhibit characteristics that make cluster analysis particularly challenging, such as missing values, outliers, and cluster features like skewness. Typically, such data would need to be preprocessed -- by cleaning outliers…

Methodology · Statistics 2025-12-16 Jason Pillay , Cristina Tortora , Antonio Punzo , Andriette Bekker

A probabilistic clustering algorithm is proposed for the analysis of forensic DNA mixtures in which individual cells are isolated and short tandem repeats are amplified using the polymerase chain reaction to generate single cell…

Applications · Statistics 2025-10-14 Robert G. Cowell

We consider an extension of model-based clustering to the semi-supervised case, where some of the data are pre-labeled. We provide a derivation of the Bayesian Information Criterion (BIC) approximation to the Bayes factor in this setting.…

Methodology · Statistics 2016-04-28 Jordan Yoder , Carey E. Priebe

Semi-supervised clustering is the task of clustering data points into clusters where only a fraction of the points are labelled. The true number of clusters in the data is often unknown and most models require this parameter as an input.…

Machine Learning · Computer Science 2013-09-27 Amar Shah , Zoubin Ghahramani

We are concerned in clustering continuous data sets subject to non-ignorable missingness. We perform clustering with a specific semi-parametric mixture, under the assumption of conditional independence given the component. The mixture model…

Methodology · Statistics 2021-07-20 Marie Du Roy de Chaumaray , Matthieu Marbac

In this paper, a scale mixture of Normal distributions model is developed for classification and clustering of data having outliers and missing values. The classification method, based on a mixture model, focuses on the introduction of…

Machine Learning · Statistics 2017-11-23 G. Revillon , A. Djafari , C. Enderli

This paper deals with the problem of clustering data returned by a radar sensor network that monitors a region where multiple moving targets are present. The network is formed by nodes with limited functionalities that transmit the…

Signal Processing · Electrical Eng. & Systems 2024-05-07 Linjie Yan , Pia Addabbo , Nicomino Fiscante , Carmine Clemente , Chengpeng Hao , Gaetano Giunta , Danilo Orlando

Variable selection in cluster analysis is important yet challenging. It can be achieved by regularization methods, which realize a trade-off between the clustering accuracy and the number of selected variables by using a lasso-type penalty.…

Methodology · Statistics 2016-12-23 Marbac Matthieu , Sedki Mohammed