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Mixed-integer optimisation problems can be computationally challenging. Here, we introduce and analyse two efficient algorithms with a specific sequential design that are aimed at dealing with sampled problems within this class. At each…

Optimization and Control · Mathematics 2023-03-07 Mohammadreza Chamanbaz , Roland Bouffanais

Machine-learning models that learn from data to predict how protein sequence encodes function are emerging as a useful protein engineering tool. However, when using these models to suggest new protein designs, one must deal with the vast…

Quantitative Methods · Quantitative Biology 2021-07-07 Brian L. Hie , Kevin K. Yang

Logistic regression is a widely used statistical model to describe the relationship between a binary response variable and predictor variables in data sets. It is often used in machine learning to identify important predictor variables.…

Optimization and Control · Mathematics 2021-12-30 Jérôme Darbon , Gabriel P. Langlois

Nonlinear Mixed effects models are hidden variables models that are widely used in many fields such as pharmacometrics. In such models, the distribution characteristics of hidden variables can be specified by including several parameters…

Methodology · Statistics 2021-10-19 Edouard Ollier

In cell line perturbation experiments, a collection of cells is perturbed with external agents (e.g. drugs) and responses such as protein expression measured. Due to cost constraints, only a small fraction of all possible perturbations can…

Applications · Statistics 2022-07-21 James P. Long , Yumeng Yang , Kim-Anh Do

In this work, we address the challenge of efficiently modeling dynamical systems in process engineering. We use reduced-order model learning, specifically operator inference. This is a non-intrusive, data-driven method for learning…

Numerical Analysis · Mathematics 2024-07-31 Ion Victor Gosea , Luisa Peterson , Pawan Goyal , Jens Bremer , Kai Sundmacher , Peter Benner

Over the last few years, there has been a surge in the use of learning techniques to improve the performance of optimization algorithms. In particular, the learning of branching rules in mixed integer linear programming has received a lot…

We propose a novel approach to select the best model of the data. Based on the exclusive properties of the nested models, we find the most parsimonious model containing the risk minimizer predictor. We prove the existence of probable…

Machine Learning · Computer Science 2024-09-17 Mohammad Ali Hajiani , Babak Seyfe

Stochastic resetting, the procedure of stopping and re-initializing random processes, has recently emerged as a powerful tool for accelerating processes ranging from queuing systems to molecular simulations. However, its usefulness is…

Statistical Mechanics · Physics 2025-03-18 Tommer D. Keidar , Ofir Blumer , Barak Hirshberg , Shlomi Reuveni

We use some of the largest order statistics of the random projections of a reference signal to construct a binary embedding that is adapted to signals correlated with such signal. The embedding is characterized from the analytical…

Machine Learning · Computer Science 2017-01-31 Diego Valsesia , Enrico Magli

This survey is focused on certain sequential decision-making problems that involve optimizing over probability functions. We discuss the relevance of these problems for learning and control. The survey is organized around a framework that…

Optimization and Control · Mathematics 2023-01-13 Emiland Garrabe , Giovanni Russo

In this note we describe experiments on an implementation of two methods proposed in the literature for computing regions that correspond to a notion of order statistics for multidimensional data. Our implementation, which works for any…

Computation · Statistics 2017-04-26 David L. Woodruff , Stefan Zillmann

In social sciences, studies are often based on questionnaires asking participants to express ordered responses several times over a study period. We present a model-based clustering algorithm for such longitudinal ordinal data. Assuming…

Methodology · Statistics 2024-01-29 Francesco Amato , Julien Jacques , Isabelle Prim-Allaz

Time Series Classification (TSC) covers the supervised learning problem where input data is provided in the form of series of values observed through repeated measurements over time, and whose objective is to predict the category to which…

Gridless methods show great superiority in line spectral estimation. These methods need to solve an atomic $l_0$ norm (i.e., the continuous analog of $l_0$ norm) minimization problem to estimate frequencies and model order. Since this…

Optimization and Control · Mathematics 2024-10-28 Bai Yan , Qi Zhao , Jin Zhang , J. Andrew Zhang , Xin Yao

Sequential recommendation models have achieved state-of-the-art performance using self-attention mechanism. It has since been found that moving beyond only using item ID and positional embeddings leads to a significant accuracy boost when…

Information Retrieval · Computer Science 2024-09-10 Linsey Pang , Amir Hossein Raffiee , Wei Liu , Keld Lundgaard

Competing risk analysis considers event times due to multiple causes, or of more than one event types. Commonly used regression models for such data include 1) cause-specific hazards model, which focuses on modeling one type of event while…

Applications · Statistics 2017-04-27 Jiayi Hou , Anthony Paravati , Ronghui Xu , James Murphy

We consider joint selection of fixed and random effects in general mixed-effects models. The interpretation of estimated mixed-effects models is challenging since changing the structure of one set of effects can lead to different choices of…

Methodology · Statistics 2020-02-26 Maud Delattre , Marie-Anne Poursat

In this paper we consider multi-objective optimization problems over a box. The problem is very relevant and several computational approaches have been proposed in the literature. They broadly fall into two main classes: evolutionary…

Optimization and Control · Mathematics 2022-12-08 Matteo Lapucci , Pierluigi Mansueto , Fabio Schoen

Panel count data arise in clinical trials when patients are asked to report their occurrences of events of interest periodically but the exact event times are unknown, only the count of events between two successive examinations are…

Methodology · Statistics 2025-05-29 Jiangjie Zhou , Baosheng Liang