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We propose a model to explain finite-size effects in intracellular microrheology observed in experiments. The constrained dynamics of the particles in the intracellular medium, treated as a viscoelastic medium, is described by means of a…

Soft Condensed Matter · Physics 2009-11-11 I. Santamaria-Holek , J. M. Rubi

Cell motility is one of the most fundamental phenomena underlying biological processes that maintain living organisms alive. Here we introduce a simple model to describe the motility of cells which include not only time-correlated internal…

Biological Physics · Physics 2022-07-13 T. N. Azevedo , L. G. Rizzi

Natural ecosystems are characterized by striking diversity of form and functions and yet exhibit deep symmetries emerging across scales of space, time and organizational complexity. Species-area relationships and species-abundance…

For long it has been known that specific patterns of folding are necessary for an optimally functioning brain. For instance, lissencephaly and polymicrogyria can lead to severe mental retardation, short life expectancy, epileptic seizures,…

Biological Physics · Physics 2020-04-03 Lucas da Costa Campos , Raphael Hornung , Gerhard Gompper , Jens Elgeti , Svenja Caspers

During overflow metabolism, cells excrete glycolytic byproducts when growing under aerobic conditions in a seemingly wasteful fashion. While potentially advantageous for microbes with finite oxidative capacity, its role in higher organisms…

The spatiotemporal coordination and regulation of cell proliferation is fundamental in many aspects of development and tissue maintenance. Cells have the ability to adapt their division rates in response to mechanical constraints, yet we do…

Quantitative Methods · Quantitative Biology 2024-04-25 Carles Falcó , Daniel J. Cohen , José A. Carrillo , Ruth E. Baker

This work deals with a chemotaxis model where an external source involving a sub and superquadratic growth effect contrasted by nonlocal dampening reaction influences the motion of a cell density attracted by a chemical signal. We study the…

Analysis of PDEs · Mathematics 2023-07-28 Yutaro Chiyo , Fatma Ga mze D Düzgün , Silvia Frassu , Giuseppe Viglialoro

Single-molecule tracking is a powerful way to look at the dynamic organization of plasma membranes. However, there are some limitations to its use. For example, it was recently observed, using numerical simulation, that time-averaging…

Quantitative Methods · Quantitative Biology 2009-11-13 Nicolas Destainville , Laurence Salome

Spatial correlations of the observed sizes and luminosities of galaxies can be used to estimate the magnification that arises through weak gravitational lensing. However, the intrinsic prop- erties of galaxies can be similarly correlated…

Cosmology and Nongalactic Astrophysics · Physics 2016-09-20 Sandro Ciarlariello , Robert Crittenden

Intermolecular interactions are pivotal for aggregation, solvation, and crystallization. We demonstrate that the collective strong coupling of several molecules to a single optical mode results in notable changes in the molecular…

Quantum Physics · Physics 2024-02-19 Matteo Castagnola , Tor S. Haugland , Enrico Ronca , Henrik Koch , Christian Schäfer

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

Probability · Mathematics 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

One of the main problems of observational cosmology is to determine the range in which a reliable measurement of galaxy correlations is possible. This corresponds to determine the shape of the correlation function, its possible evolution…

Cosmology and Nongalactic Astrophysics · Physics 2014-07-18 Francesco Sylos Labini , Daniil Tekhanovich , Yurij V. Baryshev

The structural diversity of the solute molecules involved in biomolecular processes necessitates the characterization of the forces between charged macromolecules beyond the point-ion description. From the field theoretic partition function…

Soft Condensed Matter · Physics 2023-06-22 Sahin Buyukdagli

The relation between the macroscopic quantum coherent nature of superfluids and the coherent properties of optical interference patterns will be utilized to examine the optical properties of superfluid hydrodynamics. A Bragg pattern imposed…

Optics · Physics 2007-05-23 James Lindesay

Computer simulations show that liquids of molecules with harmonic intramolecular bonds may have "pseudoisomorphic" lines of approximately invariant dynamics in the thermodynamic phase diagram. We demonstrate that these lines can be…

Soft Condensed Matter · Physics 2016-12-30 Andreas Elmerdahl Olsen , Jeppe C. Dyre , Thomas B. Schrøder

Reflection of a microscopic particle from a mesoscopic/macroscopic `mirror' generates two-body correlated interference from the incident and reflected particle substates and their associated mirror substates. The microscopic momentum…

Quantum Physics · Physics 2015-10-08 F. V. Kowalski , R. S. Browne

Spatial correlations of microscopic fluctuations are investigated via real-space experiments and computer simulations of colloidal glasses under steady shear. It is shown that while the distribution of one-particle fluctuations is always…

Soft Condensed Matter · Physics 2015-06-05 V. Chikkadi , S. Mandal , B. Nienhuis , D. Raabe , F. Varnik , P. Schall

The dynamical properties and mechanical functions of amorphous materials are governed by their microscopic structures, particularly the elasticity of the interaction networks, which is generally complicated by structural heterogeneity. This…

Statistical Mechanics · Physics 2018-04-11 Le Yan

Intracellular structural alterations are hallmark of several disease conditions and treatment modalities. However, robust methods to quantify these changes are scarce. In view of this, we introduce a new method to quantify structural…

The hydrodynamic effects of macromolecular crowding inside cells is often studied in vitro by using polymers as crowding reagents. Confinement of polymers inside cell-sized droplets has been shown to affect the diffusion of small molecules.…

Soft Condensed Matter · Physics 2023-04-28 Yaam Deckel , Lauren A. Lowe , Siddharth Rawat , Matthew Turner , James Luong , Anna Wang