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Related papers: Transcription fluctuation effects on biochemical o…

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Transcription factors (TFs) interact with a multitude of binding sites on DNA and partner proteins inside cells. We investigate how nonspecific binding/unbinding to such decoy binding sites affects the magnitude and time-scale of random…

Subcellular Processes · Quantitative Biology 2015-04-15 Mohammad Soltani , Pavol Bokes , Zachary Fox , Abhyudai Singh

We study the loss of coherence of electrochemical oscillations on meso- and nanosized electrodes with numeric simulations of the electrochemical master equation for a prototypical electrochemical oscillator, the hydrogen peroxide reduction…

Adaptation and Self-Organizing Systems · Physics 2017-06-29 Filippo G. Cosi , Katharina Krischer

This paper studies the impacts of stochastic load fluctuations, namely the fluctuation intensity and the changing speed of load power, on the size of the voltage stability margin. To this end, Stochastic Differential-Algebraic Equations…

Signal Processing · Electrical Eng. & Systems 2019-03-19 Georgia Pierrou , Xiaozhe Wang

The fluctuations are termed mesoscopic, when their typical size is essentially larger then the average distance between the nearest neighbors, while being much smaller than the overall system size. Since the features of mesoscopic…

Statistical Mechanics · Physics 2026-01-23 V. I. Yukalov , E. P. Yukalova

We examine a biomolecular machine involving a driven, observable process coupled to a hidden process in a kinetically cooperative manner. A stochastic thermodynamics framework is employed to analyze a fluctuation theorem for the…

Statistical Mechanics · Physics 2025-11-14 D. Evan Piephoff , Jianshu Cao

Many chemical reactions in biological cells occur at very low concentrations of constituent molecules. Thus, transcriptional gene-regulation is often controlled by poorly expressed transcription-factors, such as E.coli lac repressor with…

Quantitative Methods · Quantitative Biology 2016-09-27 O. Pulkkinen , R. Metzler

Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce broken detailed balance at the molecular scale. This molecular scale breaking of detailed balance is crucial to achieve biological functions such as…

Biological Physics · Physics 2018-05-02 F. Gnesotto , F. Mura , J. Gladrow , C. P. Broedersz

The observed variability of X-ray binaries over a wide range of time-scales can be understood in the framework of a stochastic propagation model, where viscous fluctuations at different radii induce accretion rate variability that propagate…

High Energy Astrophysical Phenomena · Physics 2017-08-18 Naveel Ahmad , Ranjeev Misra , Naseer Iqbal , Bari Maqbool , Mubashir Hamid

The spectrum and scale of fluctuations in protein structures affect the range of cell phenomena, including stability of protein structures or their fragments, allosteric transitions and energy transfer. The study presents a…

Biomolecules · Quantitative Biology 2015-05-13 Anatoly M. Ruvinsky , Ilya A. Vakser

Quantum fluctuations or other moments of a state contribute to energy expectation values and can imply interesting physical effects. In quantum cosmology, they turn out to be important for a discussion of density bounds and instabilities of…

General Relativity and Quantum Cosmology · Physics 2014-07-02 Martin Bojowald

We study a system of dynamical units, each of which shows excitable or oscillatory behavior, depending on the choice of parameters. When we couple these units with repressive bonds, we can control the duration of collective oscillations for…

Molecular Networks · Quantitative Biology 2014-02-06 Darka Labavic , Hildegard Meyer-Ortmanns

This study investigates the impact of molecular thermal fluctuations on compressible decaying isotropic turbulence using the unified stochastic particle (USP) method, encompassing both two-dimensional (2D) and three-dimensional (3D)…

Fluid Dynamics · Physics 2023-07-03 Qihan Ma , Chunxin Yang , Song Chen , Kaikai Feng , Ziqi Cui , Jun Zhang

The properties of the fluctuations large enough to induce bifurcations at open chemical systems at steady constraints are studied. The fluctuations that come from the diffusion-induced noise are considered. It is a generic for the surface…

Statistical Mechanics · Physics 2007-05-23 Maria K. Koleva , L. A. Petrov

Earlier we showed that the fine structure of the spectrum of amplitude variations in the results of measurements of the processes of different nature (in other words, the fine structure of the dispersion of results or the pattern of the…

General Physics · Physics 2007-05-23 Simon E. Shnoll

Feedback regulation in biochemical systems is fundamental to homeostasis, with failure causing disease or death. Recent work has found that cooperation between feedback and buffering---the use of reservoirs of molecules to maintain…

Optimization and Control · Mathematics 2018-02-02 Edward J. Hancock , Jordan Ang

We study by mean-field analysis and stochastic simulations chemical models for genetic toggle switches formed from pairs of genes that mutually repress each other. In order to determine the stability of the genetic switches, we make a…

Molecular Networks · Quantitative Biology 2007-05-23 Patrick B. Warren , Pieter Rein ten Wolde

Quantum reference frames are expected to differ from classical reference frames because they have to implement typical quantum features such as fluctuations and correlations. Here, we show that fluctuations and correlations of reference…

Quantum Physics · Physics 2023-01-03 Martin Bojowald , Artur Tsobanjan

In the standard picture of fully-developed turbulence, highly intermittent hydrodynamic fields are nonlinearly coupled across scales, where local energy cascades from large scales into dissipative vortices and large density gradients.…

Fluid Dynamics · Physics 2026-01-14 Ishan Srivastava , Andrew J. Nonaka , Weiqun Zhang , Alejandro L. Garcia , John B. Bell

Circadian clocks are the central timekeepers of life, allowing cells to anticipate changes between day and night. Experiments in recent years have revealed that circadian clocks can be highly stable, raising the question how reliably they…

Molecular Networks · Quantitative Biology 2016-06-22 Michele Monti , Pieter Rein ten Wolde

Because of the broken time-translation symmetry, in periodically driven vibrational systems fluctuations of different vibration components have different intensities. Fluctuations of one of the components are often squeezed, whereas…

Mesoscale and Nanoscale Physics · Physics 2020-06-26 J. S. Huber , G. Rastelli , M. J. Seitner , J. Kölbl , W. Belzig , M. I. Dykman , E. M. Weig