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This paper addresses two main challenges facing systems neuroscience today: understanding the nature and function of a) cortical feedback between sensory areas and b) correlated variability. Starting from the old idea of perception as…

Neurons and Cognition · Quantitative Biology 2015-11-20 Ralf M. Haefner , Pietro Berkes , József Fiser

The firing dynamics of biological neurons in mathematical models is often determined by the model's parameters, representing the neurons' underlying properties. The parameter estimation problem seeks to recover those parameters of a single…

Neurons and Cognition · Quantitative Biology 2022-10-05 Long Le , Yao Li

In this article, we review a class of neuro-mimetic computational models that we place under the label of spiking predictive coding. Specifically, we review the general framework of predictive processing in the context of neurons that emit…

Neurons and Cognition · Quantitative Biology 2024-09-10 Antony W. N'dri , William Gebhardt , Céline Teulière , Fleur Zeldenrust , Rajesh P. N. Rao , Jochen Triesch , Alexander Ororbia

Snapshots of "best" (or "worst") experience are known to dominate human memory and may thus also have a significant effect on future behaviour. We consider here a model of repeated decision-making where, at every time step, an agent takes…

Statistical Mechanics · Physics 2022-02-18 Evangelos Mitsokapas , Rosemary J. Harris

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

Biological Physics · Physics 2017-05-09 Marat M. Rvachev

A steadily increasing body of evidence suggests that the brain performs probabilistic inference to interpret and respond to sensory input and that trial-to-trial variability in neural activity plays an important role. The neural sampling…

Neurons and Cognition · Quantitative Biology 2017-07-07 Ilja Bytschok , Dominik Dold , Johannes Schemmel , Karlheinz Meier , Mihai A. Petrovici

We consider the information transmission problem in neurons and its possible implications for learning in neural networks. Our approach is based on recent developments in statistical physics and complexity science. Combining sensory…

Neurons and Cognition · Quantitative Biology 2025-09-30 Siddharth Kackar

Optimality principles have been useful in explaining many aspects of biological systems. In the context of neural encoding in sensory areas, optimality is naturally formulated in a Bayesian setting, as neural tuning which minimizes mean…

Neurons and Cognition · Quantitative Biology 2019-12-02 Yuval Harel , Ron Meir

We introduce a boosting algorithm to pre-process data for fairness. Starting from an initial fair but inaccurate distribution, our approach shifts towards better data fitting while still ensuring a minimal fairness guarantee. To do so, it…

Machine Learning · Statistics 2023-08-16 Alexander Soen , Hisham Husain , Richard Nock

Bayesian deep learning approaches assume model parameters to be latent random variables and infer posterior distributions to quantify uncertainty, increase safety and trust, and prevent overconfident and unpredictable behavior. However,…

Machine Learning · Computer Science 2023-07-13 Jihao Andreas Lin , Joe Watson , Pascal Klink , Jan Peters

The brain is believed to implement probabilistic reasoning and to represent information via population, or distributed, coding. Most previous population-based probabilistic (PPC) theories share several basic properties: 1) continuous-valued…

Neurons and Cognition · Quantitative Biology 2018-02-23 Gerard Rinkus

Active inference proposes expected free energy as an objective for planning and decision-making to adequately balance exploitative and explorative drives in learning agents. The exploitative drive, or what an agent wants to achieve, is…

Artificial Intelligence · Computer Science 2025-12-04 Filippo Torresan , Ryota Kanai , Manuel Baltieri

Guiding behavior requires the brain to make predictions about future sensory inputs. Here we show that efficient predictive computation starts at the earliest stages of the visual system. We estimate how much information groups of retinal…

Neurons and Cognition · Quantitative Biology 2013-07-02 Stephanie E. Palmer , Olivier Marre , Michael J. Berry , William Bialek

Numerous studies have shown that neuronal responses are modulated by stimulus properties, and also by the state of the local network. However, little is known about how activity fluctuations of neuronal populations modulate the sensory…

Neurons and Cognition · Quantitative Biology 2017-11-07 Iñigo Arandia-Romero , Seiji Tanabe , Jan Drugowitsch , Adam Kohn , Rubén Moreno-Bote

Research showed that, the information transmitted in biological neurons is encoded in the instants of successive action potentials or their firing rate. In addition to that, in-vivo operation of the neuron makes measurement difficult and…

Neurons and Cognition · Quantitative Biology 2018-01-10 Ozgur Doruk , Kechen Zhang

Behavioral experiments on humans and animals suggest that the brain performs probabilistic inference to interpret its environment. Here we present a new general-purpose, biologically-plausible neural implementation of approximate inference.…

Neurons and Cognition · Quantitative Biology 2016-05-24 Rajkumar Vasudeva Raju , Xaq Pitkow

Spike train signals recorded from a large population of neurons often exhibit low-dimensional spatio-temporal structure and modeled as conditional Poisson observations. The low-dimensional signals that capture internal brain states are…

Neurons and Cognition · Quantitative Biology 2024-08-19 Hyungju Jeon , Il Memming Park

Cortical circuits exhibit high levels of response diversity, even across apparently uniform neuronal populations. While emerging data-driven approaches exploit this heterogeneity to infer effective models of cortical circuit computation…

Neurons and Cognition · Quantitative Biology 2025-11-06 Mohammadreza Soltanipour , Stefan Treue , Fred Wolf

Understanding how deep learning models represent data is currently difficult due to the limited number of methodologies available. This paper demonstrates a versatile and novel visualisation tool for determining the axis alignment of…

Machine Learning · Computer Science 2025-05-21 George Bird

Probabilistic predictions are probability distributions over the set of possible outcomes. Such predictions quantify the uncertainty in the outcome, making them essential for effective decision making. By combining multiple predictions, the…

Machine Learning · Statistics 2024-11-26 Sam Allen , David Ginsbourger , Johanna Ziegel