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In mathematical studies of the dynamics of multi-strain diseases caused by antigenically diverse pathogens, there is a substantial interest in analytical insights. Using the example of a generic model of multi-strain diseases with…

Chaotic Dynamics · Physics 2015-11-13 K. B. Blyuss

We examine the properties of a recently proposed model for antigenic variation in malaria which incorporates multiple epitopes and both long-lasting and transient immune responses. We show that in the case of a vanishing decay rate for the…

Chaotic Dynamics · Physics 2012-09-21 K. B. Blyuss , S. Gupta

In this paper, a mathematical model of pneumococcal pneumonia with time delays is proposed. The stability theory of delay differential equations is used to analyze the model. The results show that the disease-free equilibrium is…

Populations and Evolution · Quantitative Biology 2019-01-16 Fulgensia Kamugisha Mbabazi , Joseph Y. T. Mugisha , Mark Kimathi

The aim of this paper is to study the steady states of the mathematical models with delay kernels which describe pathogen-immune dynamics of many kinds of infectious diseases. In the study of mathematical models of infectious diseases it is…

Dynamical Systems · Mathematics 2007-05-23 M. Neamtu , L. Buliga , F. R. Horhat , D. Opris , A. T. Ceausu

In the studies of dynamics of pathogens and their interactions with a host immune system, an important role is played by the structure of antigenic variants associated with a pathogen. Using the example of a model of antigenic variation in…

Chaotic Dynamics · Physics 2013-02-22 K. B. Blyuss

We study a mathematical model describing the dynamics of a pluripotent stem cell population involved in the blood production process in the bone marrow. This model is a differential equation with a time delay. The delay describes the cell…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Shigui Ruan

We study the effects of discrete, randomly distributed time delays on the dynamics of a coupled system of self-propelling particles. Bifurcation analysis on a mean field approximation of the system reveals that the system possesses patterns…

Pattern Formation and Solitons · Physics 2015-06-05 Luis Mier-y-Teran-Romero , Brandon Lindley , Ira B. Schwartz

We investigate a diffusive, stage-structured epidemic model with the maturation delay and freely-moving delay. Choosing delays and diffusive rates as bifurcation parameters, the only possible way to destabilize the endemic equilibrium is…

Dynamical Systems · Mathematics 2018-05-25 Yanfei Du , Ben Niu , Junjie Wei

This paper is devoted to the study of the stability of limit cycles of a nonlinear delay differential equation with a distributed delay. The equation arises from a model of population dynamics describing the evolution of a pluripotent stem…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Andrei Halanay , Mihaela Neamtu , Dumitru Opris

In this paper, we consider the dynamics of a delayed reaction-diffusion mussel-algae system subject to Neumann boundary conditions. When the delay is zero, we show the existence of positive solutions and the global stability of the boundary…

Dynamical Systems · Mathematics 2019-10-23 Zuolin Shen , Junjie Wei

This article proposes a non-autonomous mathematical model with delay for confrontation between two countries, and examines the stability of its equilibrium state. Our criteria for stability take into account the influence of the factor of…

Dynamical Systems · Mathematics 2026-05-14 Teresa Faria , Anatoliy A. Martynyuk

In this paper, we study the existence and the property of the Hopf bifurcation in the two-strategy replicator dynamics with distributed delays. In evolutionary games, we assume that a strategy would take an uncertain time delay to have a…

Systems and Control · Computer Science 2017-03-21 Nesrine Ben Khalifa , Rachid El Azouzi , Yezekael Hayel

We analyze the asymptotic stability of a nonlinear system of two differential equations with delay describing the dynamics of blood cell production. This process takes place in the bone marrow where stem cells differentiate throughout…

Analysis of PDEs · Mathematics 2009-04-17 Fabien Crauste

We investigate the effect of time delay on the dynamical model of love. The local stability analysis proves that the time delay on the return function can cause a Hopf bifurcation and a cyclic love dynamics. The condition for the occurrence…

Chaotic Dynamics · Physics 2018-02-14 Woo-Sik Son , Young-Jai Park

We investigate a time-delayed epidemic model for multi-strain diseases with temporary immunity. In the absence of cross-immunity between strains, dynamics of each individual strain exhibits emergence and anni- hilation of limit cycles due…

Adaptation and Self-Organizing Systems · Physics 2018-05-21 Larissa Bauer , Jason Bassett , Philipp Hövel , Yuliya N. Kyrychko , Konstantin B. Blyuss

We study the emergence of symmetric oscillatory behavior in multi-agent systems where each agent incorporates a continuous memory of its past states and past rates of change, modeled by distributed retarded and neutral delays. The…

Dynamical Systems · Mathematics 2026-04-23 Casey Crane

This paper analyses the dynamics of infectious disease with a concurrent spread of disease awareness. The model includes local awareness due to contacts with aware individuals, as well as global awareness due to reported cases of infection…

Populations and Evolution · Quantitative Biology 2017-04-21 G. O. Agaba , Y. N. Kyrychko , K. B. Blyuss

We consider a delay differential equation that occurs in the study of chronic myelogenous leukemia. After shortly reminding some previous results concerning the stability of equilibrium solutions, we concentrate on the study of stability of…

Dynamical Systems · Mathematics 2010-03-23 Anca-Veronica Ion , Raluca-Mihaela Georgescu

In this paper we study a model of HCV with mitotic proliferation, a saturation infection rate and a discrete intracellular delay: the delay corresponds to the time between infection of a infected target hepatocytes and production of new HCV…

Dynamical Systems · Mathematics 2014-03-13 E. Avila-Vales , N. Chan-Chí , G. García-Almeida , C. Vargas-De-León

In this paper, we develop a dynamic model of HIV infection that incorporates latent hosts, cytotoxic T lymphocyte (CTL) immunity, saturated incidence rates, and two transmission mechanisms: virus-to-cell and cell-to-cell transmission. The…

Dynamical Systems · Mathematics 2025-11-25 Songbo Hou , Xinxin Tian
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