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Cells are often considered input-output devices that maximize the transmission of information by converting extracellular stimuli (input) via signaling pathways (communication channel) to cell behavior (output). However, in biological…

Cell Behavior · Quantitative Biology 2019-11-04 Gabriele Micali , Robert G. Endres

Besides mimicking bio-chemical and multi-scale communication mechanisms, molecular communication forms a theoretical framework for virus infection processes. Towards this goal, aerosol and droplet transmission has recently been modeled as a…

Information Theory · Computer Science 2021-01-29 Peter Adam Hoeher , Martin Damrath , Sunasheer Bhattacharjee , Max Schurwanz

Diffusive molecular communication (DMC) is envisioned as a promising approach to help realize healthcare applications within bounded biological environments. In this paper, a DMC system within a biological spherical environment is…

Signal Processing · Electrical Eng. & Systems 2018-11-15 Hamidreza Arjmandi , Mohammad Zoofaghari , Adam Noel

Cells must continuously sense and respond to time-varying environmental stimuli. These signals are transmitted and processed by biochemical signalling networks. However, the biochemical reactions making up these networks are intrinsically…

Molecular Networks · Quantitative Biology 2015-05-18 Filipe Tostevin , Pieter Rein ten Wolde

The study of Molecular Communication(MC) is more and more prevalence, and channel model of MC plays an important role in the MC System. Since different propagation environment and modulation techniques produce different channel model, most…

Emerging Technologies · Computer Science 2016-03-14 Pengfei Lu , Yang You , Bo Liu , Zhenqiang Wu

A ubiquitous way that cells share information is by exchanging molecules. Yet, the fundamental ways that this information exchange is influenced by intracellular dynamics remain unclear. Here we use information theory to investigate a…

Biological Physics · Physics 2020-07-23 Amir Erez , Tommy A. Byrd , Michael Vennettilli , Andrew Mugler

Intercellular signaling has an important role in organism development, but not all communication occurs using the same mechanism. Here, we analyze the energy efficiency of intercellular signaling by two canonical mechanisms: diffusion of…

Quantitative Methods · Quantitative Biology 2022-11-30 Hyunjoong Kim , Yoichiro Mori , Joshua B. Plotkin

Molecular Communication (MC) architectures suffer from molecular build-up in the channel if they do not have appropriate reuptake mechanisms. The molecular build-up either leads to intersymbol interference (ISI) or reduces the transmission…

Molecular Networks · Quantitative Biology 2024-02-27 Caglar Koca , Ozgur B. Akan

Living organisms survive and multiply even though they have uncertain and incomplete information about their environment and imperfect models to predict the consequences of their actions. Bayesian models have been proposed to face this…

Emerging Technologies · Computer Science 2015-11-13 Jacques Droulez , David Colliaux , Audrey Houillon , Pierre Bessière

Signal propagation over long distances is a ubiquitous feature of multicellular communities. In biofilms of the bacterium Bacillus subtilis, we recently discovered that some, but not all, cells participate in the propagation of an…

Biological Physics · Physics 2020-07-01 Xiaoling Zhai , Joseph W. Larkin , Kaito Kikuchi , Samuel E. Redford , Gürol M. Süel , Andrew Mugler

Molecular communication (MC) enables information exchange at the nano- and microscale, with applications in areas like drug delivery and health monitoring. These event-driven scenarios often require alternatives to traditional transmission.…

Information Theory · Computer Science 2025-06-18 Yaning Zhao , Luca Miszewski , Christian Deppe , Massimiliano Pierobon

A molecular communication channel is determined by the received signal. Received signal models form the basis for studies focused on modulation, receiver design, capacity, and coding depend on the received signal models. Therefore, it is…

Emerging Technologies · Computer Science 2016-11-21 H. Birkan Yilmaz , Changmin Lee , Yae Jee Cho , Chan-Byoung Chae

The intestinal microbiota plays important roles in digestion and resistance against entero-pathogens. As with other ecosystems, its species composition is resilient against small disturbances but strong perturbations such as antibiotics can…

Quantitative Methods · Quantitative Biology 2015-06-04 Vanni Bucci , Serena Bradde , Giulio Biroli , Joao B. Xavier

Cells receive signaling molecules by receptors and relay information via sensory networks so that they can respond properly depending on the type of signal. Recent studies have shown that cells can extract multi-dimensional information from…

Biological Physics · Physics 2018-02-14 Yoshihiko Hasegawa

This article examines recent research in molecular communications from a telecommunications system design perspective. In particular, it focuses on channel models and state-of-the-art physical layer techniques. The goal is to provide a…

Emerging Technologies · Computer Science 2015-07-28 Weisi Guo , Taufiq Asyhari , Nariman Farsad , H. Birkan Yilmaz , Bin Li , Andrew Eckford , Chan-Byoung Chae

Information delivery using chemical molecules is an integral part of biology at multiple distance scales and has attracted recent interest in bioengineering and communication theory. Potential applications include cooperative networks with…

Information Theory · Computer Science 2017-09-05 Yansha Deng , Adam Noel , Weisi Guo , Arumugam Nallanathan , Maged Elkashlan

Microbes require several complex organic molecules for growth. A species may obtain a required factor by taking up molecules released by other species or by synthesizing the molecule. The patterns of uptake and synthesis set a flow of…

Populations and Evolution · Quantitative Biology 2014-02-27 Steven A. Frank

Arterial blood pressure is a key vital sign for the health of the human body. As such, accurate and reproducible measurement techniques are necessary for successful diagnosis. Blood pressure measurement is an example of molecular…

Information Theory · Computer Science 2014-10-22 Malcolm Egan , Adam Noel , Yansha Deng , Maged Elkashlan , Trung Q. Duong

Human communication systems, such as language, evolve culturally; their components undergo reproduction and variation. However, a role for selection in cultural evolutionary dynamics is less clear. Often neutral evolution (also known as…

Social and Information Networks · Computer Science 2014-07-01 Nicolas Fay , Monica Tamariz , T Mark Ellison , Dale Barr

Error-correcting codes are efficient methods for handling \emph{noisy} communication channels in the context of technological networks. However, such elaborate methods differ a lot from the unsophisticated way biological entities are…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-05-24 Pierre Fraigniaud , Emanuele Natale
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