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Missing data is a common problem in clinical data collection, which causes difficulty in the statistical analysis of such data. In this article, we consider the problem under a framework of a semiparametric partially linear model when…

Methodology · Statistics 2022-06-13 Zishu Zhan , Xiangjie Li , Jingxiao Zhang

A useful technique for analyzing incomplete tables is to model the missing data mechanisms of the variables using log-linear models. In this paper, we use log-linear parametrization and propose estimation methods for arbitrary three-way and…

Methodology · Statistics 2019-10-29 S. Ghosh , P. Vellaisamy

When inferring parameters from a Gaussian-distributed data set by computing a likelihood, a covariance matrix is needed that describes the data errors and their correlations. If the covariance matrix is not known a priori, it may be…

Cosmology and Nongalactic Astrophysics · Physics 2016-01-27 Elena Sellentin , Alan F. Heavens

Widely used methods for analyzing missing data can be biased in small samples. To understand these biases, we evaluate in detail the situation where a small univariate normal sample, with values missing at random, is analyzed using either…

Statistics Theory · Mathematics 2017-03-27 Paul T. von Hippel

Missing data occur frequently in a wide range of applications. In this paper, we consider estimation of high-dimensional covariance matrices in the presence of missing observations under a general missing completely at random model in the…

Methodology · Statistics 2016-05-17 T. Tony Cai , Anru Zhang

We propose a random-effects approach to missing values for generalized linear mixed model (GLMM) analysis. The method converts a GLMM with missing covariates to another GLMM without missing covariates. The standard GLMM analysis tools for…

Methodology · Statistics 2026-01-01 Thuan Nguyen , Jiangshan Zhang , Jiming Jiang

A full parametric and linear specification may be insufficient to capture complicated patterns in studies exploring complex features, such as those investigating age-related changes in brain functional abilities. Alternatively, a partially…

Methodology · Statistics 2024-02-07 Jia Liang , Shuo Chen , Peter Kochunov , L Elliot Hong , Chixiang Chen

We study the problem of maximum likelihood estimation for general patterns of bivariate missing data for normal and multinomial random variables, under the assumption that the data is missing at random (MAR). For normal data, the score…

Statistics Theory · Mathematics 2007-09-07 Serkan Hosten , Seth Sullivant

A sample covariance matrix $\boldsymbol{S}$ of completely observed data is the key statistic in a large variety of multivariate statistical procedures, such as structured covariance/precision matrix estimation, principal component analysis,…

Methodology · Statistics 2021-04-20 Seongoh Park , Xinlei Wang , Johan Lim

Missing data is an universal problem in statistics. We develop a unified framework for estimating parameters defined by general estimating equations under a missing-at-random (MAR) mechanism, based on generalized entropy calibration…

Methodology · Statistics 2026-03-31 Mst Moushumi Pervin , Hengfang Wang , Jae Kwang Kim

Estimation of genewise variance arises from two important applications in microarray data analysis: selecting significantly differentially expressed genes and validation tests for normalization of microarray data. We approach the problem by…

Statistics Theory · Mathematics 2010-11-11 Jianqing Fan , Yang Feng , Yue S. Niu

Difficulties may arise when analyzing longitudinal data using mixed-effects models if there are nonparametric functions present in the linear predictor component. This study extends the use of semiparametric mixed-effects modeling in cases…

Methodology · Statistics 2024-02-05 Mozhgan Taavoni , Mohammad Arashi

Missing covariate data commonly occur in epidemiological and clinical research, and are often dealt with using multiple imputation (MI). Imputation of partially observed covariates is complicated if the substantive model is non-linear (e.g.…

Methodology · Statistics 2014-02-17 Jonathan W. Bartlett , Shaun R. Seaman , Ian R. White , James R. Carpenter

In many applied fields incomplete covariate vectors are commonly encountered. It is well known that this can be problematic when making inference on model parameters, but its impact on prediction performance is less understood. We develop a…

Methodology · Statistics 2020-07-14 Garritt L. Page , Fernando A. Quintana , Peter Müller

We consider the estimation of high-dimensional network structures from partially observed Markov random field data using a penalized pseudo-likelihood approach. We fit a misspecified model obtained by ignoring the missing data problem. We…

Statistics Theory · Mathematics 2011-08-16 Yves F. Atchade

Item nonresponse is frequently encountered in practice. Ignoring missing data can lose efficiency and lead to misleading inference. Fractional imputation is a frequentist approach of imputation for handling missing data. However, the…

Methodology · Statistics 2018-09-18 Hejian Sang , Jae Kwang Kim

In this paper, we study the problem of high-dimensional approximately low-rank covariance matrix estimation with missing observations. We propose a simple procedure computationally tractable in high-dimension and that does not require…

Statistics Theory · Mathematics 2012-05-14 Karim Lounici

In longitudinal data a response variable is measured over time, or under different conditions, for a cohort of individuals. In many situations all intended measurements are not available which results in missing values. If the missing value…

Methodology · Statistics 2022-08-10 Ahmed M. Gad , Nesma M. Darwish

Parameter estimation in linear errors-in-variables models typically requires that the measurement error distribution be known (or estimable from replicate data). A generalized method of moments approach can be used to estimate model…

Methodology · Statistics 2018-12-04 Linh Nghiem , Michael Byrd , Cornelis Potgieter

This paper proposes a hierarchical method for estimating the location parameters of a multivariate vector in the presence of missing data. At i th step of this procedure an estimate of the location parameters for non-missing components of…

Statistics Theory · Mathematics 2007-06-13 Sergey Tarima , Yuriy Dmitriev , Richard Kryscio