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Phenotypic evolution implies sequential fixations of new genomic sequences. The speed at which these mutations fixate depends, in part, on the relative fitness (selection coefficient) of the mutant vs. the ancestor. Using a simple…

Populations and Evolution · Quantitative Biology 2014-02-04 Sorin Tanase-Nicola , Ilya Nemenman

Genetically identical cells in the same population can take on phenotypically variable states, leading to differentiated responses to external signals, such as nutrients and drug-induced stress. Many models and experiments have focused on a…

Molecular Networks · Quantitative Biology 2015-04-28 Thierry Mora , Aleksandra M. Walczak

The possibility of complicated dynamic behaviour driven by non-linear feedbacks in dynamical systems has revolutionized science in the latter part of the last century. Yet despite examples of complicated frequency dynamics, the possibility…

Populations and Evolution · Quantitative Biology 2017-02-07 Iaroslav Ispolatov , Michael Doebeli

Molecular phenotypes link genomic information with organismic functions, fitness, and evolution. Quantitative traits are complex phenotypes that depend on multiple genomic loci. In this paper, we study the adaptive evolution of a…

Populations and Evolution · Quantitative Biology 2015-06-19 Torsten Held , Armita Nourmohammad , Michael Lässig

We study the evolutionary dynamics of a maladapted population of self-replicating sequences on strongly correlated fitness landscapes. Each sequence is assumed to be composed of blocks of equal length and its fitness is given by a linear…

Populations and Evolution · Quantitative Biology 2015-05-18 Sarada Seetharaman , Kavita Jain

Living species, ranging from bacteria to animals, exist in environmental conditions that exhibit spatial and temporal heterogeneity which requires them to adapt. Risk-spreading through spontaneous phenotypic variations is a known concept in…

Populations and Evolution · Quantitative Biology 2020-04-03 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

Two mathematical models of macroevolution are studied. These models have population dynamics at the species level, and mutations and extinction of species are also included. The population dynamics are updated by difference equations with…

Populations and Evolution · Quantitative Biology 2014-04-16 Yohsuke Murase , Takashi Shimada , Nobuyasu Ito , Per Arne Rikvold

We use the context of dryland vegetation to study a general problem of complex pattern forming systems - multiple pattern-forming instabilities that are driven by distinct mechanisms but share the same spectral properties. We find that the…

Pattern Formation and Solitons · Physics 2013-11-05 Shai Kinast , Yuval R. Zelnik , Golan Bel , Ehud Meron

Coevolving and competing species or game-theoretic strategies exhibit rich and complex dynamics for which a general theoretical framework based on finite populations is still lacking. Recently, an explicit mean-field description in the form…

Statistical Mechanics · Physics 2007-05-23 Arne Traulsen , Jens Christian Claussen , Christoph Hauert

Genetic sequences are known to possess non-trivial composition together with symmetries in the frequencies of their components. Recently, it has been shown that symmetry and structure are hierarchically intertwined in DNA, suggesting a…

Genomics · Quantitative Biology 2020-09-28 Giampaolo Cristadoro , Mirko Degli Esposti , Eduardo G. Altmann

Many biological systems regulate phenotypic heterogeneity as a fitness-maximising strategy in uncertain and dynamic environments. Analysis of such strategies is typically confined both to a discrete set of environmental conditions, and to a…

Populations and Evolution · Quantitative Biology 2025-07-02 Alexander P Browning , Sara Hamis

The study of stochastic systems has received considerable interest over the years. Their dynamics can describe many equilibrium and nonequilibrium fluctuating systems. At the same time, nonequilibrium constraints interact with the time…

Statistical Mechanics · Physics 2011-03-14 David Andrieux

The evolutionary mechanisms of cooperative behavior represent a fundamental topic in complex systems and evolutionary dynamics. Real-world collective interactions, particularly in multi-agent systems, are often characterized by…

Adaptation and Self-Organizing Systems · Physics 2026-02-23 Yishen Jiang , Xin Wang , Wenqiang Zhu , Ming Wei , Longzhao Liu , Shaoting Tang , Hongwei Zheng

The maintenance of diversity, the `commonness of rarity', and compositional turnover are ubiquitous features of species-rich communities. Through a minimal model, we consider how these features reflect the interplay between environmental…

Populations and Evolution · Quantitative Biology 2025-12-04 Emil Mallmin , Arne Traulsen , Silvia De Monte

We study the influence of complex graphs on the metastability and fixation properties of a set of evolutionary processes. In the framework of evolutionary game theory, where the fitness and selection are frequency-dependent and vary with…

Statistical Mechanics · Physics 2012-11-01 Michael Assaf , Mauro Mobilia

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

In classical evolutionary theory, genetic variation provides the source of heritable phenotypic variation on which natural selection acts. Against this classical view, several theories have emphasized that developmental variability and…

Populations and Evolution · Quantitative Biology 2011-11-08 Steven A. Frank

Network coherence generally refers to the emergence of simple aggregated dynamical behaviours, despite heterogeneity in the dynamics of the subsystems that constitute the network. In this paper, we develop a general frequency domain…

Systems and Control · Electrical Eng. & Systems 2023-02-17 Hancheng Min , Richard Pates , Enrique Mallada

The time-dependent probability density function of a system evolving towards a stationary state exhibits an oscillatory behavior if the eigenvalues of the corresponding evolution operator are complex. The frequencies \omega_n, with which…

Statistical Mechanics · Physics 2012-06-22 R. Salgado-Garcia

Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inheritance of a gradualistic view that has been challenged at…

Populations and Evolution · Quantitative Biology 2018-07-27 Jacobo Aguirre , Pablo Catalán , José A. Cuesta , Susanna Manrubia