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Documentation is one of the most neglected activities in Software Engineering, although it is an important method of assuring quality and understanding. Bioinformatics software is generally written by researchers from fields other than…

Software Engineering · Computer Science 2023-05-09 Vinicius Soares Silva Marques , Laurence Rodrigues do Amaral

While automated experiments and high-throughput methods are becoming more mainstream in the age of data, empowering individual researchers to capture, collate, and contextualize their data faster and more reproducibly still remains a…

Computers and Society · Computer Science 2020-07-30 Ha-Kyung Kwon , Chirranjeevi Balaji Gopal , Jared Kirschner , Santiago Caicedo , Brian D. Storey

Quantum computing is fast evolving as a technology due to recent advances in hardware, software, as well as the development of promising applications. To use this technology for solving specific problems, a suitable quantum algorithm has to…

Quantum Physics · Physics 2024-06-25 Nils Quetschlich , Lukas Burgholzer , Robert Wille

The collaboration of several people in groups is becoming more and more important nowadays. Teamwork is often used for decision-making processes and for solving complex problems. Research in this area focuses on the quantification and…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-01-16 Michael Hopfengaertner

We present a workflow and associated toolkit to automate the creation of graphical user interfaces (GUI) for executables run from command line interfaces (CLI). The workflow consists of three phases, namely (Step 1) the plugin design, (Step…

Human-Computer Interaction · Computer Science 2026-02-19 Sikao Guo , Edoardo Sarti , Frédéric Cazals

The computer programs most users interact with daily are driven by a graphical user interface (GUI). However, many scientific applications are used with a command line interface (CLI) for the ease of development and increased flexibility…

Human-Computer Interaction · Computer Science 2008-06-03 N. C. Manoukis , E. C. Anderson

Ontologies present an attractive technology for describing bio-medicine, because they can be shared, and have rich computational properties. However, they lack the rich expressivity of English and fit poorly with the current scientific…

Digital Libraries · Computer Science 2015-12-15 Phillip Lord , Jennifer Warrendar

Quantum computing systems depend on the principles of quantum mechanics to perform multiple challenging tasks more efficiently than their classical counterparts. In classical software engineering, the software life cycle is used to document…

Software Engineering · Computer Science 2023-07-24 Thong Hoang , Hoa Khanh Dam , Tingting Bi , Qinghua Lu , Zhenchang Xing , Liming Zhu , Lam Duc Nguyen , Shiping Chen

Mathematical models are increasingly used in both academia and the pharmaceutical industry to understand how phenotypes emerge from systems of molecular interactions. However, their current construction as monolithic sets of equations…

Molecular Networks · Quantitative Biology 2007-10-19 Aneil Mallavarapu , Matthew Thomson , Benjamin Ullian , Jeremy Gunawardena

Artificial intelligence has recently experienced remarkable advances, fueled by large models, vast datasets, accelerated hardware, and, last but not least, the transformative power of differentiable programming. This new programming…

Machine Learning · Computer Science 2025-06-25 Mathieu Blondel , Vincent Roulet

Recent developments in Artificial Intelligence techniques have enabled their successful application across a spectrum of commercial and industrial settings. However, these techniques require large volumes of data to be aggregated in a…

Cryptography and Security · Computer Science 2023-04-04 Dengsheng Chen , Vince Tan , Zhilin Lu , Jie Hu

Drug discovery is a complex, multi-step pipeline that remains heavily dependent on manual, experience-driven operations; meanwhile, existing customized artificial intelligence tools are fragmented across web applications, desktop software,…

Biomolecules · Quantitative Biology 2026-03-03 Qihua Pan , Dong Xu , Qianwei Yang , Jenna Xinyi Yao , Sisi Yuan , Zexuan Zhu , Jianqiang Li , Junkai Ji

Recent progress in large language models (LLMs) has advanced automatic code generation, yet most approaches rely on direct, single-step translation from problem descriptions to code, disregarding structured software engineering practices.…

Software Engineering · Computer Science 2025-10-29 Xing Xing , Wei Wang , Lipeng Ma , Weidong Yang , Junjie Zheng

One key challenge in Artificial Life is designing systems that display an emergence of complex behaviors. Many such systems depend on a high-dimensional parameter space, only a small subset of which displays interesting dynamics. Focusing…

Adaptation and Self-Organizing Systems · Physics 2024-03-11 Vassilis Papadopoulos , Guilhem Doat , Arthur Renard , Clément Hongler

Brain Computer Interface (BCI) technologies have the potential to improve the lives of millions of people around the world, whether through assistive technologies or clinical diagnostic tools. Despite advancements in the field, however, at…

Machine Learning · Computer Science 2023-01-31 Chad Mello , Troy Weingart , Ethan M. Rudd

Radio astronomy observatories with high throughput back end instruments require real-time data processing. While computing hardware continues to advance rapidly, development of real-time processing pipelines remains difficult and…

It is time-consuming and error-prone to implement inference procedures for each new probabilistic model. Probabilistic programming addresses this problem by allowing a user to specify the model and having a compiler automatically generate…

Diffusion models, emerging as powerful deep generative tools, excel in various applications. They operate through a two-steps process: introducing noise into training samples and then employing a model to convert random noise into new…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Huijie Zhang , Yifu Lu , Ismail Alkhouri , Saiprasad Ravishankar , Dogyoon Song , Qing Qu

Computing has revolutionized the biological sciences over the past several decades, such that virtually all contemporary research in the biosciences utilizes computer programs. The computational advances have come on many fronts, spurred by…

Other Quantitative Biology · Quantitative Biology 2021-08-23 Berk Ekmekci , Charles E. McAnany , Cameron Mura

In this work, we deal with the problem of computing a comprehensive front of efficient solutions in multi-objective portfolio optimization problems in presence of sparsity constraints. We start the discussion pointing out some weaknesses of…

Optimization and Control · Mathematics 2025-09-23 Arturo Annunziata , Matteo Lapucci , Pieluigi Mansueto , Davide Pucci
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