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Related papers: Disease processes as hybrid dynamical systems

200 papers

Major advances have been made regarding the utilization of artificial intelligence in health care. In particular, deep learning approaches have been successfully applied for automated and assisted disease diagnosis and prognosis based on…

Methodology · Statistics 2020-03-24 Max Westphal , Antonia Zapf , Werner Brannath

Mathematical models are crucial for optimizing and controlling chemical processes, yet they often face significant limitations in terms of computational time, algorithm complexity, and development costs. Hybrid models, which combine…

Mobile genetic elements like conjugative plasmids play a crucial role in shaping the genetic content and population dynamics of bacterial species. Bacterial populations often contain not one, but multiple co-circulating MGEs, which modify…

Populations and Evolution · Quantitative Biology 2025-04-25 Berit Siedentop , Jana S. Huisman , Claudia Igler

The study of infectious disease epidemiology for multi-type disease pathogens requires modelling techniques that account for the complex interactions existing between strains across geography and time. In this paper, we propose a novel…

Methodology · Statistics 2026-05-06 Matthew Adeoye , Simon E. F. Spencer , Xavier Didelot

The general idea of this article is to develop a Bayesian model with a flexible link function connecting an exponential family treatment response to a linear combination of covariates and a treatment indicator and the interaction between…

Methodology · Statistics 2022-05-05 Hyung Park , Danni Wu , Eva Petkova , Thaddeus Tarpey , R. Todd Ogden

In this paper we study a discrete-time SIS (susceptible-infected-susceptible) model, where the infection and healing parameters and the underlying network may change over time. We provide conditions for the model to be well-defined and…

Systems and Control · Electrical Eng. & Systems 2020-10-23 Philip E Pare , Sebin Gracy , Henrik Sandberg , Karl Henrik Johansson

In response to the COVID-19 pandemic, the integration of interpretable machine learning techniques has garnered significant attention, offering transparent and understandable insights crucial for informed clinical decision making. This…

Machine Learning · Computer Science 2024-09-10 Jinzhi Shen , Ke Ma

One of the most significant challenges in combating against the spread of infectious diseases was the difficulty in estimating the true magnitude of infections. Unreported infections could drive up disease spread, making it very hard to…

Social and Information Networks · Computer Science 2025-02-04 Jiaming Cui , Bijaya Adhikari , Arash Haddadan , A S M Ahsan-Ul Haque , Jilles Vreeken , Anil Vullikanti , B. Aditya Prakash

Identifying clinically relevant biomarkers and developing predictive models are central challenges in biomedical research. Biomarkers are commonly used for disease screening, and some provide information not only on the presence or absence…

Methodology · Statistics 2025-08-21 Kazuharu Harada , Shuichi Kawano , Masataka Taguri

Epidemiological processes are studied within a recently proposed hierarchical network model using the susceptible-infected-refractory dynamics of an epidemic. Within the network model, a population may be characterized by $H$ independent…

Disordered Systems and Neural Networks · Physics 2008-06-24 Dafang Zheng , P. M. Hui , Steffen Trimper , Bo Zheng

In this paper, we introduce a general framework for co-infection as cooperative SIR dynamics. We first solve analytically CGCG model [1] and then the generalized model in symmetric scenarios. We calculate transition points, order parameter,…

Populations and Evolution · Quantitative Biology 2019-07-24 Fatemeh Zarei , Saman Moghimi-Araghi , Fakhteh Ghanbarnejad

Foundation large language models (LLMs) have shown an impressive ability to solve tasks across a wide range of fields including health. To effectively solve personalized health tasks, LLMs need the ability to ingest a diversity of data…

Motivated by disease progression-related studies, we propose an estimation method for fitting general non-homogeneous multi-state Markov models. The proposal can handle many types of multi-state processes, with several states and various…

Methodology · Statistics 2024-07-22 Alessia Eletti , Giampiero Marra , Rosalba Radice

We present a computational modeling framework for data-driven simulations and analysis of infectious disease spread in large populations. For the purpose of efficient simulations, we devise a parallel solution algorithm targeting…

Populations and Evolution · Quantitative Biology 2018-02-19 Pavol Bauer , Stefan Engblom , Stefan Widgren

Recent deep learning research based on Transformer model architectures has demonstrated state-of-the-art performance across a variety of domains and tasks, mostly within the computer vision and natural language processing domains. While…

Machine Learning · Computer Science 2021-11-11 Benjamin Shickel , Patrick J. Tighe , Azra Bihorac , Parisa Rashidi

This paper explores the advancements and applications of language models in healthcare, focusing on their clinical use cases. It examines the evolution from early encoder-based systems requiring extensive fine-tuning to state-of-the-art…

Artificial Intelligence · Computer Science 2025-05-12 Nikita Neveditsin , Pawan Lingras , Vijay Mago

Multiple-type branching processes that model the spread of infectious diseases are investigated. In these stochastic processes, the disease goes through multiple stages before it eventually disappears. We mostly focus on the critical…

Populations and Evolution · Quantitative Biology 2015-06-04 Tibor Antal , P. L. Krapivsky

When studying the evolution of complex systems one refers to model representations comprising various descriptive parameters. There is hardly research where system evolution is described on the base of information flows in the system. The…

Computers and Society · Computer Science 2021-06-17 Inga A. Ivanova

Disease awareness in infection dynamics can be modeled with adaptive contact networks whose rewiring rules reflect the attempt by susceptibles to avoid infectious contacts. Simulations of this type of models show an active phase with…

Adaptation and Self-Organizing Systems · Physics 2012-12-06 Stefan Wieland , Tomas Aquino , Ana Nunes

Since the outbreak of COVID-19, an astronomical number of publications on the pandemic dynamics appeared in the literature, of which many use the susceptible infected removed (SIR) and susceptible exposed infected removed (SEIR) models, or…

Machine Learning · Computer Science 2021-11-03 Hua-Liang Wei , S. A. Billings