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Recent work has shown that probabilistic models based on pairwise interactions-in the simplest case, the Ising model-provide surprisingly accurate descriptions of experiments on real biological networks ranging from neurons to genes.…

Quantitative Methods · Quantitative Biology 2007-12-18 Tamara Broderick , Miroslav Dudik , Gasper Tkacik , Robert E. Schapire , William Bialek

Feature selection, identifying a subset of variables that are relevant for predicting a response, is an important and challenging component of many methods in statistics and machine learning. Feature selection is especially difficult and…

Quantitative Methods · Quantitative Biology 2014-08-01 Charles K. Fisher , Pankaj Mehta

Several powerful machines, such as the D-Wave 2000Q, dedicated to solving combinatorial optimization problems through the Ising-model formulation have been developed. To input problems into the machines, the unknown parameters on the Ising…

This paper addresses the problem of sparsity penalized least squares for applications in sparse signal processing, e.g. sparse deconvolution. This paper aims to induce sparsity more strongly than L1 norm regularization, while avoiding…

Machine Learning · Computer Science 2015-06-15 Ivan W. Selesnick , Ilker Bayram

This paper discusses a class of thresholding-based iterative selection procedures (TISP) for model selection and shrinkage. People have long before noticed the weakness of the convex $l_1$-constraint (or the soft-thresholding) in wavelets…

Statistics Theory · Mathematics 2009-11-29 Yiyuan She

Estimating covariance parameters for multivariate spatial Gaussian random fields is computationally challenging, as the number of parameters grows rapidly with the number of variables, and likelihood evaluation requires operations of order…

Methodology · Statistics 2026-04-10 Francisco Cuevas-Pacheco , Gabriel Riffo , Xavier Emery

A variable screening procedure via correlation learning was proposed Fan and Lv (2008) to reduce dimensionality in sparse ultra-high dimensional models. Even when the true model is linear, the marginal regression can be highly nonlinear. To…

Methodology · Statistics 2011-01-19 Jianqing Fan , Yang Feng , Rui Song

The Lasso is biased. Concave penalized least squares estimation (PLSE) takes advantage of signal strength to reduce this bias, leading to sharper error bounds in prediction, coefficient estimation and variable selection. For prediction and…

Statistics Theory · Mathematics 2017-12-29 Long Feng , Cun-Hui Zhang

We propose a unified framework for likelihood-based regression modeling when the response variable has finite support. Our work is motivated by the fact that, in practice, observed data are discrete and bounded. The proposed methods assume…

Methodology · Statistics 2022-09-13 Karl Oskar Ekvall , Matteo Bottai

Popular sparse estimation methods based on $\ell_1$-relaxation, such as the Lasso and the Dantzig selector, require the knowledge of the variance of the noise in order to properly tune the regularization parameter. This constitutes a major…

Machine Learning · Statistics 2013-04-17 Arnak S. Dalalyan , Mohamed Hebiri , Katia Méziani , Joseph Salmon

Gibbs point processes (GPPs) constitute a large and flexible class of spatial point processes with explicit dependence between the points. They can model attractive as well as repulsive point patterns. Feature selection procedures are an…

Statistics Theory · Mathematics 2021-01-22 Ismaïla Ba , Jean-François Coeurjolly

We propose a new approach for metric learning by framing it as learning a sparse combination of locally discriminative metrics that are inexpensive to generate from the training data. This flexible framework allows us to naturally derive…

Machine Learning · Computer Science 2019-01-25 Yuan Shi , Aurélien Bellet , Fei Sha

This study introduces a general semiparametric clusterwise index distribution model to analyze how latent clusters affect the covariate-response relationships. By employing sufficient dimension reduction to account for the effects of…

Methodology · Statistics 2025-09-30 Jen-Chieh Teng , Chin-Tsang Chiang

Sparse learning is a very important tool for mining useful information and patterns from high dimensional data. Non-convex non-smooth regularized learning problems play essential roles in sparse learning, and have drawn extensive attentions…

Machine Learning · Computer Science 2020-10-22 Guannan Liang , Qianqian Tong , Jiahao Ding , Miao Pan , Jinbo Bi

Several convex formulation methods have been proposed previously for statistical estimation with structured sparsity as the prior. These methods often require a carefully tuned regularization parameter, often a cumbersome or heuristic…

Machine Learning · Statistics 2016-03-23 Sohail Bahmani , Petros T. Boufounos , Bhiksha Raj

We investigate the learning performance of the pseudolikelihood maximization method for inverse Ising problems. In the teacher-student scenario under the assumption that the teacher's couplings are sparse and the student does not know the…

Disordered Systems and Neural Networks · Physics 2020-08-26 Alia Abbara , Yoshiyuki Kabashima , Tomoyuki Obuchi , Yingying Xu

We propose a doubly robust estimator for the average treatment effect in high dimensional low sample size observational studies, where contamination and model misspecification pose serious inferential challenges. The estimator combines…

Methodology · Statistics 2025-11-04 Byeonghee Lee , Sangwook Kang , Ju-Hyun Park , Saebom Jeon , Joonsung Kang

The aim of this paper is to introduce an adaptive penalized estimator for identifying the true reduced parametric model under the sparsity assumption. In particular, we deal with the framework where the unpenalized estimator of the…

Statistics Theory · Mathematics 2020-11-02 Alessandro De Gregorio , Francesco Iafrate

We consider the problem of estimation of a covariance matrix for Gaussian data in a high dimensional setting. Existing approaches include maximum likelihood estimation under a pre-specified sparsity pattern, l_1-penalized loglikelihood…

Methodology · Statistics 2024-10-04 Luca Cibinel , Alberto Roverato , Veronica Vinciotti

The popular Lasso approach for sparse estimation can be derived via marginalization of a joint density associated with a particular stochastic model. A different marginalization of the same probabilistic model leads to a different…

Machine Learning · Statistics 2013-02-28 Aleksandr Y. Aravkin , James V. Burke , Alessandro Chiuso , Gianluigi Pillonetto