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Accurate estimate of nucleation rate is crucial for the study of ice nucleation and ice-promoting/anti-freeze strategies. Within the framework of Classical Nucleation Theory (CNT), the estimate of ice nucleation rate is very sensitive to…

Soft Condensed Matter · Physics 2021-07-07 Chaohong Wang , Hao Wang , Jianyang Wu , Zhisen Zhang

The classical nucleation theory for homogeneous nucleation is formulated as a theory for a density fluctuation in a supersaturated gas at a given temperature. But Molecular Dynamics simulations reveal that it is small cold clusters which…

Other Condensed Matter · Physics 2015-10-28 Søren Toxvaerd

Most spherical viruses exhibit icosahedral symmetry, yet the growth of viral shells remains poorly understood due to the short lifetimes and broad size distribution of assembly intermediates. Classical nucleation theory has been widely…

Soft Condensed Matter · Physics 2026-03-10 Alexander Bryan Clark , Paul van der Schoot , Henri Orland , Roya Zandi

Recently, it was shown that a theoretical description of nucleation based on fluctuating hydrodynamics and classical density functional theory can be used to determine non-classical nucleation pathways for crystallization (Lutsko, Sci. Adv.…

Chemical Physics · Physics 2024-06-26 James F. Lutsko , Cédric Schoonen

A recently formulated description of homogeneous nucleation for Brownian particles in the over-damped limit based on fluctuating hydrodynamics is used to determine the nucleation pathway, characterized as the most likely path (MLP), for the…

Soft Condensed Matter · Physics 2012-10-18 James F. Lutsko

We revisit classical nucleation theory (CNT) for the homogeneous bubble nucleation rate and improve the classical formula using a new prefactor in the nucleation rate. Most of the previous theoretical studies have used the constant…

Chemical Physics · Physics 2015-07-19 Kyoko K. Tanaka , Hidekazu Tanaka , Raymond Angélil , Jürg Diemand

Nucleation is an out-of-equilibrium process, which can be strongly affected by the presence of external fields. In this letter, we report a simple extension of classical nucleation theory to systems submitted to an homogeneous shear flow.…

Statistical Mechanics · Physics 2013-06-17 Anatolii V. Mokshin , Bulat N. Galimzyanov , Jean-Louis Barrat

We performed molecular dynamics (MD) simulations of the nucleation of water vapor in order to test nucleation theories. Simulations were performed for a wide range of supersaturation ratios (S = 3-25) and water temperatures (Tw=300-390K).…

Chemical Physics · Physics 2015-06-18 Kyoko K. Tanaka , Akio Kawano , Hidekazu Tanaka

A full understanding of polycrystalline materials requires studying the process of nucleation, a thermally activated phase transition that typically occurs at atomistic scales. The numerical modeling of this process is problematic for…

Materials Science · Physics 2018-05-09 Paul Jreidini , Gabriel Kocher , Nikolas Provatas

Phase diagrams of some globular proteins have a fluid-fluid transition as well as a fluid-crystal transition. Homogeneous nucleation of the crystal from the fluid phase near the critical point of the fluid-fluid transition is examined. As…

Soft Condensed Matter · Physics 2009-10-31 Richard P. Sear

Using state-of-the-art rare-event sampling simulations, we precisely characterize the nucleation of liquid droplets from a supersaturated Lennard-Jones gas and uncover a key physical feature: critical clusters nucleate with a density that…

Chemical Physics · Physics 2026-01-07 Yijian Wu , Thomas Philippe , Aymane Graini , Julien Lam

Molecular dynamics simulations are widely used to investigate nucleation in first-order phase transitions. Brute-force simulations, though popular, are limited to conditions of high metastability, where the critical cluster and the…

Chemical Physics · Physics 2026-02-10 Thomas Philippe , Yijian Wu , Aymane Graini

Recent theories of nucleation that go beyond Classical Nucleation Theory predict that diffusion-limited nucleation of both liquid droplets and of crystals from a low-density vapor (or weak solution) begins with long-wavelength density…

Statistical Mechanics · Physics 2020-05-27 James F. Lutsko , Julien Lam

Non-aligning self-propelled particles with purely repulsive excluded volume interactions undergo athermal motility-induced phase separation into a dilute gas and a dense cluster phase. Here, we use enhanced sampling computational methods…

Soft Condensed Matter · Physics 2016-10-05 Gabriel S. Redner , Caleb G. Wagner , Aparna Baskaran , Michael F. Hagan

The critical radius of a nucleus grown by diffusion in a solution is studied thermodynamically as well as kinetically. The thermodynamic growth equation called Zeldovich equation of classical nucleation theory (CNT) and the kinetic…

Soft Condensed Matter · Physics 2014-03-05 Masao Iwamatsu

Structural aspects of crystal nucleation in undercooled liquids are explored using a nonlinear hydrodynamic theory of crystallization proposed recently [G. I. Toth et al., J. Phys.: Condens. Matter 26, 055001 (2014)], which is based on…

Materials Science · Physics 2017-05-24 Frigyes Podmaniczky , Gyula I. Toth , Gyorgy Tegze , Laszlo Granasy

Homogeneous nucleation, a textbook transition path for phase transitions, is typically understood on thermodynamic grounds through the prism of classical nucleation theory. However, recent studies have suggested the applicability of…

Soft Condensed Matter · Physics 2025-12-08 Luke Langford , Ahmad K. Omar

We present a new model of homogeneous aggregation that contains the essential physical ideas of the classical predecessors, the Becker-Doring and Lifshitz-Slyovoz models. These classical models, which give different predictions, are…

Materials Science · Physics 2007-05-23 Yossi Farjoun , John C. Neu

In standard nucleation theory, the nucleation process is characterized by computing $\Delta\Omega(V)$, the reversible work required to form a cluster of volume $V$ of the stable phase inside the metastable mother phase. However, other…

Statistical Mechanics · Physics 2015-06-18 Santi Prestipino , Alessandro Laio , Erio Tosatti

The well-known classical nucleation theory (CNT) for the free energy barrier towards formation of a nucleus of critical size of the new stable phase within the parent metastable phase fails to take into account the influence of other…

Statistical Mechanics · Physics 2015-06-18 Rakesh S. Singh , Biman Bagchi