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The long-term growth rate of populations in varying environments quantifies the evolutionary value of processing the information that biological individuals inherit from their ancestors and acquire from their environment. Previous models…

Populations and Evolution · Quantitative Biology 2021-06-30 Anton S Zadorin , Olivier Rivoire

Leveraging the vast genetic diversity within microbiomes offers unparalleled insights into complex phenotypes, yet the task of accurately predicting and understanding such traits from genomic data remains challenging. We propose a framework…

Genomics · Quantitative Biology 2025-03-05 Zhufeng Li , Sandeep S Cranganore , Nicholas Youngblut , Niki Kilbertus

The mechanisms by which adaptive phenotypes spread within an evolving population after their emergence are understood fairly well. Much less is known about the factors that influence the evolutionary accessibility of such phenotypes, a…

Populations and Evolution · Quantitative Biology 2015-05-13 Wilfred Ndifon , Joshua B. Plotkin , Jonathan Dushoff

Source-sink systems are metapopulations of habitat patches with different, and possibly temporally varying, habitat qualities, which are commonly used in ecology to study the fate of spatially extended natural populations. We propose new…

Probability · Mathematics 2012-10-18 Vincent Bansaye , Amaury Lambert

One of the most intriguing questions in evolution is how organisms exhibit suitable phenotypic variation to rapidly adapt in novel selective environments which is crucial for evolvability. Recent work showed that when selective environments…

Populations and Evolution · Quantitative Biology 2015-08-28 Kostas Kouvaris , Jeff Clune , Louis Kounios , Markus Brede , Richard A. Watson

The impact of climate change on populations will be contingent upon their contemporary adaptive evolution. In this study, we investigated the contemporary evolution of four populations of the cold-water kelp Laminaria digitata by analysing…

Populations and Evolution · Quantitative Biology 2024-04-23 Lauric Reynes , Louise Fouqueau , D. Aurelle , Stéphane Mauger , Christophe Destombe , Myriam Valero

Most population models assume that individuals within a given population are identical, that is, the fundamental role of variation is ignored. Here we develop a general approach to modeling heterogeneous populations with discrete…

Populations and Evolution · Quantitative Biology 2007-05-23 Georgy P. Karev , Artem S. Novozhilov , Faina S. Berezovskaya

Identifying undocumented or potential future interactions among species is a challenge facing modern ecologists. Recent link prediction methods rely on trait data, however large species interaction databases are typically sparse and…

Applications · Statistics 2019-09-23 Mohamad Elmasri , Maxwell J. Farrell , T. Jonathan Davies , David A. Stephens

The fitness landscape encodes the mapping of genotypes to fitness and provides a succinct representation of possible trajectories followed by an evolving population. Evolutionary accessibility is quantified by the existence of…

Populations and Evolution · Quantitative Biology 2021-06-30 Joachim Krug

We analyze the long-term stability of a stochastic model designed to illustrate the adaptation of a population to variation in its environment. A piecewise-deterministic process modeling adaptation is coupled to a Feller logistic diffusion…

Probability · Mathematics 2021-09-14 Aurélien Velleret

Evolution is the theory that plants and animals today have come from kinds that have existed in the past. Scientists such as Charles Darwin and Alfred Wallace dedicate their life to observe how species interact with their environment, grow,…

Neural and Evolutionary Computing · Computer Science 2022-09-16 Manasa Josyula

The role of positive selection in human evolution remains controversial. On the one hand, scans for positive selection have identified hundreds of candidate loci and the genome-wide patterns of polymorphism show signatures consistent with…

Populations and Evolution · Quantitative Biology 2013-08-23 David Enard , Philipp W. Messer , Dmitri Petrov

Receptive field profiles registered by cell recordings have shown that mammalian vision has developed receptive fields tuned to different sizes and orientations in the image domain as well as to different image velocities in space-time.…

Neurons and Cognition · Quantitative Biology 2014-04-09 Tony Lindeberg

The size distribution of grains is a fundamental characteristic of polycrystalline solids. In the absence of deformation, the grain-size distribution is controlled by normal grain growth. The canonical model of normal grain growth,…

Materials Science · Physics 2021-02-04 Thomas Breithaupt , Lars N. Hansen , Srikanth Toppaladoddi , Richard F. Katz

Comparing allele frequencies among populations that differ in environment has long been a tool for detecting loci involved in local adaptation. However, such analyses are complicated by an imperfect knowledge of population allele…

Populations and Evolution · Quantitative Biology 2012-09-17 Torsten Günther , Graham Coop

The functions of proteins and RNAs are determined by a myriad of interactions between their constituent residues, but most quantitative models of how molecular phenotype depends on genotype must approximate this by simple additive effects.…

Quantitative Methods · Quantitative Biology 2017-12-19 Adam J. Riesselman , John B. Ingraham , Debora S. Marks

Natural selection at one site shapes patterns of genetic variation at linked sites. Quantifying the effects of 'linked selection' on levels of genetic diversity is key to making reliable inference about demography, building a null model in…

Populations and Evolution · Quantitative Biology 2016-08-30 Eyal Elyashiv , Shmuel Sattath , Tina T. Hu , Alon Strustovsky , Graham McVicker , Peter Andolfatto , Graham Coop , Guy Sella

Most of the DNA that composes a complex organism is non-coding and defined as junk. Even the coding part is composed of genes that affect the phenotype differently. Therefore, a random mutation has an effect on the specimen fitness that…

Populations and Evolution · Quantitative Biology 2021-07-19 Mattia Miotto , Lorenzo Monacelli

Human populations have experienced dramatic growth since the Neolithic revolution. Recent studies that sequenced a very large number of individuals observed an extreme excess of rare variants, and provided clear evidence of recent rapid…

Populations and Evolution · Quantitative Biology 2015-06-17 Elodie Gazave , Li Ma , Diana Chang , Alex Coventry , Feng Gao , Donna Muzny , Eric Boerwinkle , Richard Gibbs , Charles F. Sing , Andrew G. Clark , Alon Keinan

The response of dynamical systems to varying conditions and disturbances is a fundamental aspect of their analysis. In spatially extended systems, particularly in pattern-forming systems, there are many possible responses, including…

Pattern Formation and Solitons · Physics 2017-03-02 Yuval R. Zelnik , Ehud Meron , Golan Bel