Related papers: Highly Efficient Factorial Designs for cDNA Microa…
DNA microarray experiments, a well-established experimental technique, aim at understanding the function of genes in some biological processes. One of the most common experiments in functional genomics research is to compare two groups of…
High-dimensional measurements are often correlated which motivates their approximation by factor models. This holds also true when features are engineered via low-dimensional interactions or kernel tricks. This often results in over…
We present a novel approach for designing complex approximate arithmetic circuits that trade correctness for power consumption and play important role in many energy-aware applications. Our approach integrates in a unique way formal methods…
Factors models are routinely used to analyze high-dimensional data in both single-study and multi-study settings. Bayesian inference for such models relies on Markov Chain Monte Carlo (MCMC) methods which scale poorly as the number of…
Biological visual systems learn from limited experience, unlike deep learning models that rely on millions of training images. What learning principles make this possible? We tested whether efficient coding, the idea that neural…
In this paper a novel computational technique for finite discrete approximation of continuous dynamical systems suitable for a significant class of biochemical dynamical systems is introduced. The method is parameterized in order to affect…
For large classes of group testing problems, we derive lower bounds for the probability that all significant items are uniquely identified using specially constructed random designs. These bounds allow us to optimize parameters of the…
We propose a general methodology of sequential locally optimal design of experiments for explicit or implicit nonlinear models, as they abound in chemical engineering and, in particular, in vapor-liquid equilibrium modeling. As a sequential…
A lately created metaheuristic algorithm called Child Drawing Development Optimization (CDDO) has proven to be effective in a number of benchmark tests. A Binary Child Drawing Development Optimization (BCDDO) is suggested for choosing the…
One of the most challenging tasks in microarray image analysis is spot segmentation. A solution to this problem is to provide an algorithm than can be used to find any spot within the microarray image. Circular Hough Transformation (CHT) is…
Approximate dynamic programming has been used successfully in a large variety of domains, but it relies on a small set of provided approximation features to calculate solutions reliably. Large and rich sets of features can cause existing…
The techniques of data-driven backmapping from coarse-grained (CG) to fine-grained (FG) representation often struggle with accuracy, unstable training, and physical realism, especially when applied to complex systems such as proteins. In…
History-dependent constitutive models serve as macroscopic closures for the aggregated effects of micromechanics. Their parameters are typically learned from experimental data. With a limited experimental budget, eliciting the full range of…
The minimum aberration criterion has been frequently used in the selection of fractional factorial designs with nominal factors. For designs with quantitative factors, however, level permutation of factors could alter their geometrical…
Learning rich and compact representations is an open topic in many fields such as object recognition or image retrieval. Deep neural networks have made a major breakthrough during the last few years for these tasks but their representations…
The crucial step in designing a particle filter for a particular application is the choice of importance density. The optimal scheme is to use the conditional posterior density of the state, but this cannot be sampled or calculated…
Graph sampling theory extends the traditional sampling theory to graphs with topological structures. As a key part of the graph sampling theory, subset selection chooses nodes on graphs as samples to reconstruct the original signal. Due to…
We consider fairness in submodular maximization subject to a knapsack constraint, a fundamental problem with various applications in economics, machine learning, and data mining. In the model, we are given a set of ground elements, each…
The horseshoe prior is frequently employed in Bayesian analysis of high-dimensional models, and has been shown to achieve minimax optimal risk properties when the truth is sparse. While optimization-based algorithms for the extremely…
Determining the causal structure of a set of variables is critical for both scientific inquiry and decision-making. However, this is often challenging in practice due to limited interventional data. Given that randomized experiments are…