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Kingman's coalescent is a random tree that arises from classical population genetic models such as the Moran model. The individuals alive in these models correspond to the leaves in the tree and the following two laws of large numbers…

Probability · Mathematics 2014-06-24 Andrej Depperschmidt , Peter Pfaffelhuber , Annika Scheuringer

Populations evolving under the joint influence of recombination and resampling (traditionally known as genetic drift) are investigated. First, we summarise and adapt a deterministic approach, as valid for infinite populations, which assumes…

Populations and Evolution · Quantitative Biology 2009-02-20 Ellen Baake , Inke Herms

We consider neutral evolution of a large population subject to changes in its population size. For a population with a time-variable carrying capacity we have computed the distributions of the total branch lengths of its sample genealogies.…

Populations and Evolution · Quantitative Biology 2012-06-13 A. Eriksson , B. Mehlig , M. Rafajlovic , S. Sagitov

When an advantageous mutation occurs in a population, the favorable allele may spread to the entire population in a short time, an event known as a selective sweep. As a result, when we sample $n$ individuals from a population and trace…

Probability · Mathematics 2007-05-23 Rick Durrett , Jason Schweinsberg

We identify a new natural coalescent structure, which we call the seed-bank coalescent, that describes the gene genealogy of populations under the influence of a strong seed-bank effect, where "dormant forms" of individuals (such as seeds…

Probability · Mathematics 2016-08-10 Jochen Blath , Adrián González Casanova , Noemi Kurt , Maite Wilke-Berenguer

The advent of modern genome sequencing techniques allows for a more stringent test of the neutrality hypothesis of Darwinian evolution, where all individuals have the same fitness. Using the individual based model of Wright and Fisher, we…

Populations and Evolution · Quantitative Biology 2017-02-01 Bahram Houchmandzadeh

We introduce a stochastic model of a population with overlapping generations and arbitrary levels of self-fertilization versus outcrossing. We study how the global graph of reproductive relationships, or population pedigree, influences the…

Populations and Evolution · Quantitative Biology 2025-05-20 Maximillian Newman , John Wakeley , Wai-Tong Louis Fan

The purpose of this Note is twofold: First, we introduce the general formalism of evolutionary genetics dynamics involving fitnesses, under both the deterministic and stochastic setups, and chiefly in discrete-time. In the process, we…

Quantitative Methods · Quantitative Biology 2015-05-14 Thierry Huillet

The entropy rates of the Wright-Fisher process, the Moran process, and generalizations are computed and used to compare these processes and their dependence on standard evolutionary parameters. Entropy rates are measures of the variation…

Dynamical Systems · Mathematics 2014-03-26 Marc Harper

In population genetics, diffusions on the unit interval are often used to model the frequency path of an allele. In this setting we derive approximations for fixation probabilities, expected hitting times and the expected…

Probability · Mathematics 2018-09-18 Peter Pfaffelhuber , Anton Wakolbinger

We study a class of processes that are akin to the Wright-Fisher model, with transition probabilities weighted in terms of the frequency-dependent fitness of the population types. By considering an approximate weak formulation of the…

Populations and Evolution · Quantitative Biology 2014-08-28 Fabio A. C. C. Chalub , Max O. Souza

We study a universal object for the genealogy of a sample in populations with mutations: the critical birth-death process with Poissonian mutations, conditioned on its population size at a fixed time horizon. We show how this process arises…

Probability · Mathematics 2014-07-30 G. Achaz , C. Delaporte , A. Lambert

Phylodynamics seeks to estimate effective population size fluctuations from molecular sequences of individuals sampled from a population of interest. One way to accomplish this task formulates an observed sequence data likelihood exploiting…

$\Lambda$-Wright--Fisher processes provide a robust framework to describe the type-frequency evolution of an infinite neutral population. We add a polynomial drift to the corresponding stochastic differential equation to incorporate…

Probability · Mathematics 2023-04-26 Fernando Cordero , Sebastian Hummel , Emmanuel Schertzer

Temporal environmental variations are ubiquitous in nature, yet most of the theoretical works in population genetics and evolution assume fixed environment. Here we analyze the effect of variations in carrying capacity on the fate of a…

Populations and Evolution · Quantitative Biology 2019-12-16 Immanuel Meyer , Nadav M. Shnerb

Standard neutral population genetics theory with a strictly fixed population size has important limitations. An alternative model that allows independently fluctuating population sizes and reproduces the standard neutral evolution is…

Populations and Evolution · Quantitative Biology 2017-03-08 Thiparat Chotibut , David R. Nelson

Population genetics theory has laid the foundations for genomics analyses including the recent burst in genome scans for selection and statistical inference of past demographic events in many prokaryote, animal and plant species.…

Populations and Evolution · Quantitative Biology 2014-01-22 Aurelien Tellier , Christophe Lemaire

Modern developments in population dynamics emphasize the role of the turnover of individuals. In the new approaches stable population size is a dynamic equilibrium between different mortality and fecundity factors instead of an arbitrary…

Populations and Evolution · Quantitative Biology 2014-03-05 Krzysztof Argasinski , Mark Broom

We consider a continuous population whose dynamics is described by the standard stationary Fleming-Viot process, so that the genealogy of $n$ uniformly sampled individuals is distributed as the Kingman $n$-coalescent. In this note, we study…

Probability · Mathematics 2016-11-07 Amaury Lambert , Emmanuel Schertzer

This work is a systematic study of discrete Markov chains that are used to describe the evolution of a two-types population. Motivated by results valid for the well-known Moran (M) and Wright-Fisher (WF) processes, we define a general class…

Populations and Evolution · Quantitative Biology 2017-05-02 Fabio A. C. C. Chalub , Max O. Souza