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Many cells exhibit large-scale active circulation of their entire fluid contents, a process termed cytoplasmic streaming. This phenomenon is particularly prevalent in plant cells, often presenting strikingly regimented flow patterns. The…

Soft Condensed Matter · Physics 2013-08-30 Francis G. Woodhouse , Raymond E. Goldstein

The swimming of cells, far from any boundary, can arise in the absence of long-range liquid-crystalline order within the cytoplasm, but simple models of this effect are lacking. Here we present a two-dimensional model of droplet…

Soft Condensed Matter · Physics 2020-07-29 Rajesh Singh , Elsen Tjhung , Michael E. Cates

Concentrated suspensions of swimming microorganisms and other forms of active matter are known to display complex, self-organized spatio-temporal patterns on scales large compared to those of the individual motile units. Despite intensive…

Soft Condensed Matter · Physics 2014-07-15 Enkeleida Lushi , Hugo Wioland , Raymond E Goldstein

Large cells often rely on cytoplasmic flows for intracellular transport, maintaining homeostasis, and positioning cellular components. Understanding the mechanisms of these flows is essential for gaining insights into cell function,…

Fluid Dynamics · Physics 2023-11-09 Brato Chakrabarti , Stanislav Y. Shvartsman , Michael J. Shelley

In the cellular phenomena of cytoplasmic streaming, molecular motors carrying cargo along a network of microtubules entrain the surrounding fluid. The piconewton forces produced by individual motors are sufficient to deform long…

Soft Condensed Matter · Physics 2021-01-20 David B. Stein , Gabriele De Canio , Eric Lauga , Michael J. Shelley , Raymond E. Goldstein

Motivated by the observation of highly unstable flowing states in suspensions of microtubules and kinesin, we analyze a model of mutually-propelled filaments suspended in a solvent. The system undergoes a mean-field isotropic-nematic…

Soft Condensed Matter · Physics 2015-05-30 L. Giomi , L. Mahadevan , B. Chakraborty , M. F. Hagan

We simulate the nonlocal Stokesian hydrodynamics of an elastic filament which is active due a permanent distribution of stresslets along its contour. A bending instability of an initially straight filament spontaneously breaks flow symmetry…

Recent experiments on active materials, such as dense bacterial suspensions and microtubule-kinesin motor mixtures, show a promising potential for achieving self-sustained flows. However, to develop active microfluidics it is necessary to…

Soft Condensed Matter · Physics 2019-01-23 Santhan Chandragiri , Amin Doostmohammadi , Julia M Yeomans , Sumesh P Thampi

Active processes drive and guide biological dynamics across scales -- from subcellular cytoskeletal remodelling, through tissue development in embryogenesis, to population-level bacterial colonies expansion. In each of these, biological…

We use linear stability analysis and hybrid lattice Boltzmann simulations to study the dynamical behaviour of an active nematic confined in a channel made of viscoelastic material. We find that the quiescent, ordered active nematic is…

Soft Condensed Matter · Physics 2023-12-20 Francesco Mori , Saraswat Bhattacharyya , Julia M. Yeomans , Sumesh P. Thampi

We numerically study the dynamics of a passive fluid droplet confined within a microchannel whose walls are covered with a thin layer of active gel. The latter represents a fluid of extensile material modelling, for example, a suspension of…

Soft Condensed Matter · Physics 2023-08-10 A. Tiribocchi , M. Durve , M. Lauricella , A. Montessori , S. Succi

Many active biological particles, such as swimming microorganisms or motor-proteins, do work on their environment by going though a periodic sequence of shapes. Interactions between particles can lead to the phase-synchronization of their…

Soft Condensed Matter · Physics 2022-07-26 Brato Chakrabarti , Michael J. Shelley , Sebastian Fürthauer

We study the interplay of activity, order and flow through a set of coarse-grained equations governing the hydrodynamic velocity, concentration and stress fields in a suspension of active, energy-dissipating particles. We make several…

Soft Condensed Matter · Physics 2009-11-10 Yashodhan Hatwalne , Sriram Ramaswamy , Madan Rao , R. Aditi Simha

We investigate a two-dimensional polydisperse suspension of self-propelled semiflexible filaments and reveal a collective wrapping mechanism that is absent in monodisperse systems. At intermediate activity levels, long filaments coil around…

Active droplets are artificial microswimmers built from a liquid dispersion by microfluidic tools and showing self-propelled motion. These systems hold particular interest for mimicking biological phenomena, such as some aspects of cell…

Soft Condensed Matter · Physics 2023-06-14 Adriano Tiribocchi , Mihir Durve , Marco Lauricella , Andrea Montessori , Davide Marenduzzo , Sauro Succi

We present a theory for self-driven fluids, such as motorized cytoskeletal extracts or bacterial suspensions, that takes into account the underlying periodic duty cycle carried by the active particles of which the system is composed. We…

Soft Condensed Matter · Physics 2013-12-09 Sebastian Fürthauer , Sriram Ramaswamy

Numerical simulations in two space dimensions are used to examine the dynamics, transport, and equilibrium behaviors of a neutrally buoyant circular object immersed in an active suspension within a larger closed circular container. The…

Fluid Dynamics · Physics 2023-04-12 Jonathan B. Freund

Confining surfaces play crucial roles in dynamics, transport and order in many physical systems, but their effects on active matter, a broad class of dynamically self-organizing systems, are poorly understood. We investigate here the…

Soft Condensed Matter · Physics 2013-07-23 Hugo Wioland , Francis G. Woodhouse , Jörn Dunkel , John O. Kessler , Raymond E. Goldstein

Spontaneous growth of long-wavelength deformations is a defining feature of active fluids with orientational order. We investigate the effect of biaxial rectangular confinement on the instability of initially shear-aligned 3D isotropic…

Soft Condensed Matter · Physics 2021-01-04 Pooja Chandrakar , Minu Varghese , S. Ali Aghvami , Aparna Baskaran , Zvonimir Dogic , Guillaume Duclos

Organisms show a remarkable range of sizes, yet the dimensions of a single cell rarely exceed $100$ $\mu$m. While the physical and biological origins of this constraint remain poorly understood, exceptions to this rule give valuable…

Biological Physics · Physics 2015-05-20 Raymond E. Goldstein , Jan-Willem van de Meent
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