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Wide-field fluorescence microscopy with compact optics often suffers from spatially varying blur due to field-dependent aberrations, vignetting, and sensor truncation, while finite sensor sampling imposes an inherent trade-off between field…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Qianwan Yang , Zhixiong Chen , Jiaqi Zhang , Ruipeng Guo , Guorong Hu , Lei Tian

The interest of compressive sampling in ultrasound imaging has been recently extensively evaluated by several research teams. Following the different application setups, it has been shown that the RF data may be reconstructed from a small…

Computer Vision and Pattern Recognition · Computer Science 2015-12-07 Zhouye Chen , Adrian Basarab , Denis Kouamé

Acoustic-resolution photoacoustic microscopy (AR-PAM) is a promising tool for microvascular imaging. In the focal region, resolution of AR-PAM is determined by the ultrasound transducer and ultimately limited by acoustic diffraction. In the…

Image and Video Processing · Electrical Eng. & Systems 2021-11-22 Fei Feng , Siqi Liang , Sung-Liang Chen

We present a semi-blind, spatially-variant deconvolution technique aimed at optical microscopy that combines a local estimation step of the point spread function (PSF) and deconvolution using a spatially variant, regularized Richardson-Lucy…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Adrian Shajkofci , Michael Liebling

Methods of three-dimensional deconvolution (3DD) or volumetric deconvolution of optical complex-valued wavefronts diffracted by 3D samples with the 3D point spread function are presented. Particularly, the quantitative correctness of the…

Optics · Physics 2022-01-11 Tatiana Latychevskaia

It has previously been demonstrated that model-based reconstruction methods relying on a priori knowledge of the imaging point spread function (PSF) coupled to sparsity priors on the object to image can provide super-resolution in…

Image and Video Processing · Electrical Eng. & Systems 2019-10-02 Sergey Vilov , Bastien Arnal , Eliel Hojman , Yonina C. Eldar , Ori Katz , Emmanuel Bossy

In light-sheet microscopy, overall image content and resolution are improved by acquiring and fusing multiple views of the sample from different directions. State-of-the-art multi-view (MV) deconvolution employs the point spread functions…

Quantitative Methods · Quantitative Biology 2015-03-30 Benjamin Schmid , Jan Huisken

Convolutional neural networks (CNNs) and Vision Transformers (ViTs) have achieved excellent performance in image restoration. While ViTs generally outperform CNNs by effectively capturing long-range dependencies and input-specific…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Lingshun Kong , Jiangxin Dong , Jinhui Tang , Ming-Hsuan Yang , Jinshan Pan

While convolutional neural networks (CNNs) and vision transformers (ViTs) have advanced medical image segmentation, they face inherent limitations such as local receptive fields in CNNs and high computational complexity in ViTs. This paper…

Image and Video Processing · Electrical Eng. & Systems 2025-04-02 Pooya Ashtari , Shahryar Noei , Fateme Nateghi Haredasht , Jonathan H. Chen , Giuseppe Jurman , Aleksandra Pizurica , Sabine Van Huffel

Fluorescence microscopy plays an important role in biomedical research. The depth-variant point spread function (PSF) of a fluorescence microscope produces low-quality images especially in the out-of-focus regions of thick specimens.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-09 Da He , De Cai , Jiasheng Zhou , Jiajia Luo , Sung-Liang Chen

Acoustic-Resolution Photoacoustic Microscopy (AR-PAM) is promising for subcutaneous vascular imaging, but its spatial resolution is constrained by the Point Spread Function (PSF). Traditional deconvolution methods like Richardson-Lucy and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Youshen Xiao , Sheng Liao , Xuanyang Tian , Fan Zhang , Xinlong Dong , Yunhui Jiang , Xiyu Chen , Ruixi Sun , Yuyao Zhang , Fei Gao

Bolton and Schlegel presented a promising deconvolution method to extract 1D spectra from a 2D optical fiber spectral CCD image. The method could eliminate the PSF difference between fibers, extract spectra to the photo noise level, as well…

Instrumentation and Methods for Astrophysics · Physics 2015-06-24 Guangwei Li , Haotong Zhang , Zhongrui Bai

We present a physics-informed deep learning framework to address common limitations in Confocal Laser Scanning Microscopy (CLSM), such as diffraction limited resolution, noise, and undersampling due to low laser power conditions. The…

Materials Science · Physics 2025-01-27 Zaheer Ahmad , Junaid Shabeer , Usman Saleem , Tahir Qadeer , Abdul Sami , Zahira El Khalidi , Saad Mehmood

In this paper, we propose a novel design of image deblurring in the form of one-shot convolution filtering that can directly convolve with naturally blurred images for restoration. The problem of optical blurring is a common disadvantage to…

Image and Video Processing · Electrical Eng. & Systems 2019-07-22 Mahdi S. Hosseini , Konstantinos N. Plataniotis

We present a non-iterative method to deconvolve the spatial response function or the point spread function (PSF) from images taken with the Suzaku X-ray Imaging Spectrometer (XIS). The method is optimized for analyses of extended sources…

Astrophysics · Physics 2015-05-13 Mutsumi Sugizaki , Tuneyoshi Kamae , Yoshitomo Maeda

Beamforming is an essential step in the ultrasound image formation pipeline and has recently attracted growing interest. An important goal of beamforming is to increase the image spatial resolution, or in other words to narrow down the…

Image and Video Processing · Electrical Eng. & Systems 2022-09-01 Sobhan Goudarzi , Adrian Basarab , Hassan Rivaz

Image blurring refers to the degradation of an image wherein the image's overall sharpness decreases. Image blurring is caused by several factors. Additionally, during the image acquisition process, noise may get added to the image. Such a…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Poorna Banerjee Dasgupta

We present a variational Bayesian method of joint image reconstruction and point spread function (PSF) estimation when the PSF of the imaging device is only partially known. To solve this semi-blind deconvolution problem, prior…

Data Analysis, Statistics and Probability · Physics 2013-03-18 Se Un Park , Nicolas Dobigeon , Alfred O. Hero

Variational autoencoders (VAEs) typically encode images into a compact latent space, reducing computational cost but introducing an optimization dilemma: a higher-dimensional latent space improves reconstruction fidelity but often hampers…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Xunzhi Xiang , Xingye Tian , Guiyu Zhang , Yabo Chen , Shaofeng Zhang , Xuebo Wang , Xin Tao , Qi Fan

The desire for wide-field of view, large fractional bandwidth, high sensitivity, high spectral and temporal resolution has driven radio interferometry to the point of big data revolution where the data is represented in at least three…

Instrumentation and Methods for Astrophysics · Physics 2020-09-30 M. Atemkeng , O. Smirnov , C. Tasse , G. Foster , S. Makhathini