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Neurons in the brain continuously process the barrage of sensory inputs they receive from the environment. A wide array of experimental work has shown that the collective activity of neural populations encodes and processes this constant…

Neurons and Cognition · Quantitative Biology 2025-10-30 Siddharth Paliwal , Gabriel Koch Ocker , Braden A. W. Brinkman

Spiking Neural Networks (SNNs) use discrete spike sequences to transmit information, which significantly mimics the information transmission of the brain. Although this binarized form of representation dramatically enhances the energy…

Neural and Evolutionary Computing · Computer Science 2023-01-31 Guobin Shen , Dongcheng Zhao , Yi Zeng

Bistability is considered wide-spread among bacteria and eukaryotic cells, useful e.g. for enzyme induction, bet hedging, and epigenetic switching. However, this phenomenon has mostly been described with deterministic dynamic or well-mixed…

Subcellular Processes · Quantitative Biology 2017-02-08 Robert G. Endres

Synaptic noise plays a major role in setting up coexistence of various firing patterns, but the precise mechanisms whereby these synaptic noise contributes to coexisting firing activities are subtle and remain elusive. To investigate these…

Biological Physics · Physics 2023-03-22 Xinyi Wang , Xiyun Zhang , Muhua Zheng , Leijun Xu , Kesheng Xu

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

Neurons and Cognition · Quantitative Biology 2022-04-01 Braden A. W. Brinkman , Han Yan , Arianna Maffei , Il Memming Park , Alfredo Fontanini , Jin Wang , Giancarlo La Camera

In this paper we study noise-induced bistability in a specific circuit with many biological implications, namely a single-step enzymatic cycle described by Michaelis Menten equations with quasi-steady state assumption. We study the system…

Biological Physics · Physics 2011-07-25 Daniel Remondini , Enrico Giampieri , Armando Bazzani , Gastone Castellani , Amos Maritan

Nonlinear dynamics of spiking neural networks has recently attracted much interest as an approach to understand possible information processing in the brain and apply it to artificial intelligence. Since information can be processed by…

Spiking neural networks aim to emulate the brain's properties to achieve similar parallelism and high-processing power. A caveat of these neural networks is the high computational cost to emulate, while current proposals for analogue…

Cell-fate transition can be modeled by ordinary differential equations (ODEs) which describe the behavior of several molecules in interaction, and for which each stable equilibrium corresponds to a possible phenotype (or 'biological…

Dynamical Systems · Mathematics 2021-04-12 Nastassia Pouradier Duteil , Jules Guilberteau , Camille Pouchol , Nastassia Duteil

Consider a large number $n$ of neurons, each being connected to approximately $N$ other ones, chosen at random. When a neuron spikes, which occurs randomly at some rate depending on its electric potential, its potential is set to a minimum…

Probability · Mathematics 2020-03-19 Nicolas Fournier , Etienne Tanré , Romain Veltz

In this paper, we investigate the fundamental limits on how the inter- spike time of a neuron oscillator can be perturbed by the application of a bounded external control input (a current stimulus) with zero net electric charge…

Optimization and Control · Mathematics 2012-11-20 Isuru S. Dasanayake , Jr-Shin Li

We have studied neuronal synchronisation in a random network of adaptive exponential integrate-and-fire neurons. We study how spiking or bursting synchronous behaviour appears as a function of the coupling strength and the probability of…

We report the observation of polaritonic bistability in semiconductor microcavities in the strong coupling regime. The origin of bistability is the polariton-polariton interaction, which gives rise to a Kerr-like nonlinearity. The…

Strongly Correlated Electrons · Physics 2017-02-20 Augustin Baas , Jean-Philippe Karr , Elisabeth Giacobino

Self-organized bistability (SOB) stands as a critical behavior for the systems delicately adjusting themselves to the brink of bistability, characterized by a first-order transition. Its essence lies in the inherent ability of the system to…

Adaptation and Self-Organizing Systems · Physics 2024-01-08 Md Sayeed Anwar , Nikita Frolov , Alexander E. Hramov , Dibakar Ghosh

Inhibitory neurons play a crucial role in maintaining persistent neuronal activity. Although connected extensively through electrical synapses (gap-junctions), these neurons also exhibit interactions through chemical synapses in certain…

Neurons and Cognition · Quantitative Biology 2021-04-08 R. Janaki , A. S. Vytheeswaran

We study how the stubbornness of social network users influences opinion polarization and disagreement. Our work is in the context of the popular Friedkin-Johnson opinion formation model, where users update their opinion as a function of…

Social and Information Networks · Computer Science 2024-10-31 Mohammad Shirzadi , Ahad N. Zehmakan

We consider a new class of non Markovian processes with a countable number of interacting components. At each time unit, each component can take two values, indicating if it has a spike or not at this precise moment. The system evolves as…

Probability · Mathematics 2015-06-12 Antonio Galves , Eva Löcherbach

A binding neuron (BN) whith delayed feedback is considered. The neuron is fed externally with a Poisson stream of intensity $\lambda$. The neuron's output spikes are fed into its input with time delay $\Delta$. The resulting output stream…

Neurons and Cognition · Quantitative Biology 2014-12-09 Alexander Vidybida

This work introduces a novel methodology for designing biologically plausible bursting neuron circuits using a minimal number of components. We hypothesize that to design circuits capable of bursting, the neuron circuit design must mimic a…

Hardware Architecture · Computer Science 2025-09-23 Amr Nabil , T. Nandha Kumar , Haider Abbas F. Almurib

We study a network of spiking neurons with heterogeneous excitabilities connected via inhibitory delayed pulses. For globally coupled systems the increase of the inhibitory coupling reduces the number of firing neurons by following a Winner…

Disordered Systems and Neural Networks · Physics 2019-05-29 Stefano Luccioli , David Angulo Garcia , Alessandro Torcini
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