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A rigorous methodology is proposed to study cell division data consisting in several observed genealogical trees of possibly different shapes. The procedure takes into account missing observations, data from different trees, as well as the…

Applications · Statistics 2013-04-15 Benoîte de Saporta , Anne Gégout Petit , Laurence Marsalle

Decision trees are renowned for their ability to achieve high predictive performance while remaining interpretable, especially on tabular data. Traditionally, they are constructed through recursive algorithms, where they partition the data…

Machine Learning · Computer Science 2024-08-27 Yufan Zhuang , Liyuan Liu , Chandan Singh , Jingbo Shang , Jianfeng Gao

We propose a general framework for a collaborative machine learning system to assist bioscience researchers with the task of labeling specific cell identities from microscopic still or video imaging. The distinguishing features of this…

Quantitative Methods · Quantitative Biology 2019-03-25 Greg Bubnis , Steven Ban , Matthew D. DiFranco , Saul Kato

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

Quantitative analysis of the dynamics of tiny cellular and sub-cellular structures, known as particles, in time-lapse cell microscopy sequences requires the development of a reliable multi-target tracking method capable of tracking numerous…

Computer Vision and Pattern Recognition · Computer Science 2015-07-24 Seyed Hamid Rezatofighi , Stephen Gould , Ba Tuong Vo , Ba-Ngu Vo , Katarina Mele , Richard Hartley

String matching is one of the most fundamental problems in computer science. A natural problem is to determine the number of characters that need to be queried (i.e. the decision tree complexity) in a string in order to decide whether this…

Computational Complexity · Computer Science 2018-06-29 Xiaoyu He , Neng Huang , Xiaoming Sun

In molecular systematics, evolutionary trees are reconstructed from sequences at the tips under simple models of site substitution. A central question is how much sequence data is required to reconstruct a tree accurately? The answer…

Quantitative Methods · Quantitative Biology 2012-07-18 Iain Martyn , Mike Steel

Metabolites, small molecules that are involved in cellular reactions, provide a direct functional signature of cellular state. Untargeted metabolomics experiments usually relies on tandem mass spectrometry to identify the thousands of…

Quantitative Methods · Quantitative Biology 2015-01-29 Kai Dührkop , Sebastian Böcker

Within the domain of medical image analysis, three distinct methodologies have demonstrated commendable accuracy: Neural Networks, Decision Trees, and Ensemble-Based Learning Algorithms, particularly in the specialized context of genstro…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Zeshan Khan

A method for creating a forest of model trees to fit samples of a function defined on images is described in several steps: down-sampling the images, determining a tree's hyperplanes, applying convolutions to the hyperplanes to handle small…

Machine Learning · Computer Science 2026-01-28 William Ward Armstrong , Hongyi Li , Jun Xu

In this paper, the main task we aim to tackle is the multi-instance semi-supervised video object segmentation across a sequence of frames where only the first-frame box-level ground-truth is provided. Detection-based algorithms are widely…

Computer Vision and Pattern Recognition · Computer Science 2020-04-17 Mingjie Sun , Jimin Xiao , Eng Gee Lim , Bingfeng Zhang , Yao Zhao

We introduce a multiple testing procedure (TreeBH) which addresses the challenge of controlling error rates at multiple levels of resolution. Conceptually, we frame this problem as the selection of hypotheses which are organized…

Methodology · Statistics 2018-10-25 Marina Bogomolov , Christine B. Peterson , Yoav Benjamini , Chiara Sabatti

In recent years, significant progress has been made on algorithms for learning optimal decision trees, primarily in the context of binary features. Extending these methods to continuous features remains substantially more challenging due to…

Machine Learning · Computer Science 2026-01-22 Harold Kiossou , Pierre Schaus , Siegfried Nijssen

Plant classification and identification has so far been an important and difficult task. In this paper, an efficient and systematic approach for extracting the leaf architecture characters from captured digital images is proposed. The input…

Computer Vision and Pattern Recognition · Computer Science 2018-01-09 Mahmoud Sadeghi , Ali Zakerolhosseini , Ali Sonboli

Estimation of molecular evolutionary divergence times requires models of rate change. These vary with regard to the assumption of what quantity is penalized. The possibilities considered are the rate of evolution, the log of the rate of…

Genomics · Quantitative Biology 2007-12-31 Peter J Waddell

Plants are fundamentally important to life. Key research areas in plant science include plant species identification, weed classification using hyper spectral images, monitoring plant health and tracing leaf growth, and the semantic…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 K. K. Thyagharajan , I. Kiruba Raji

Imagine trying to track one particular fruitfly in a swarm of hundreds. Higher biological visual systems have evolved to track moving objects by relying on both appearance and motion features. We investigate if state-of-the-art deep neural…

Computer Vision and Pattern Recognition · Computer Science 2021-06-04 Drew Linsley , Girik Malik , Junkyung Kim , Lakshmi N Govindarajan , Ennio Mingolla , Thomas Serre

Cell biologists study in parallel the morphology of cells with the regulation mechanisms that modify this morphology. Such studies are complicated by the inherent heterogeneity present in the cell population. It remains difficult to define…

Quantitative Methods · Quantitative Biology 2025-12-23 Yossi Bokor Bleile , Pooja Yadav , Patrice Koehl , Florian Rehfeldt

Decision trees are a popular technique in statistical data classification. They recursively partition the feature space into disjoint sub-regions until each sub-region becomes homogeneous with respect to a particular class. The basic…

Machine Learning · Statistics 2015-04-15 D. C. Wickramarachchi , B. L. Robertson , M. Reale , C. J. Price , J. Brown

Classifier chains are an effective technique for modeling label dependencies in multi-label classification. However, the method requires a fixed, static order of the labels. While in theory, any order is sufficient, in practice, this order…

Machine Learning · Computer Science 2021-12-14 Eneldo Loza Mencía , Moritz Kulessa , Simon Bohlender , Johannes Fürnkranz