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The characterization of individual nanoparticles in a liquid constitutes a critical challenge for environmental, material, and biological sciences. To detect nanoparticles, electronic approaches are especially desirable owing to their…

In nanopore technology, the development of multiplexed detection and release platforms with high spatial and temporal resolution remains a significant challenge due to the difficulty in distinguishing signals originating from different…

Applied Physics · Physics 2025-10-16 Ali Douaki , Shukun Weng , Silvia Dante , Nako Nakatsuka , Makusu Tsutsui , Roman Krahne , Denis Garoli

Translocation through a nanopore is a new experimental technique to probe physical properties of biomolecules. A bulk of theoretical and computational work exists on the dependence of the time to translocate a single unstructured molecule…

Biomolecules · Quantitative Biology 2009-05-04 Malcolm McCauley , Robert Forties , Ulrich Gerland , Ralf Bundschuh

The scanning electron microscope (SEM) recordings of dynamic nano-electromechanical systems (NEMS) are difficult to analyze due to the noise caused by low frame rate, insufficient resolution and blurriness induced by applied electric…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Ege Erdem , Berke Demiralp , Hadi S Pisheh , Peyman Firoozy , Ahmet Hakan Karakurt , M. Selim Hanay

In nanopore sequencing, electrical signal is measured as DNA molecules pass through the sequencing pores. Translating these signals into DNA bases (base calling) is a highly non-trivial task, and its quality has a large impact on the…

Machine Learning · Computer Science 2021-05-18 Vladimír Boža , Peter Perešíni , Broňa Brejová , Tomáš Vinař

Proteins are arguably the most important class of biomarkers for health diagnostic purposes. Label-free solid-state nanopore sensing is a versatile technique for sensing and analysing biomolecules such as proteins at single-molecule level.…

A device capable of performing real time classification of proteins in a clinical setting would allow for inexpensive and rapid disease diagnosis. One such candidate for this technology are nanopore devices. These devices work by measuring…

Machine Learning · Computer Science 2025-09-18 Samuel Tovey , Julian Hoßbach , Sandro Kuppel , Tobias Ensslen , Jan C. Behrends , Christian Holm

Solid-state nanopores offer a powerful platform for nanoscale analysis of individual analytes, including biomolecules and functionalized nanoparticles, by confining them within a precisely defined sensing region. However, their inherently…

Solid-state nanopore and nanopipette sensors are powerful devices for the detection, quantification and structural analysis of biopolymers such as DNA and proteins, especially in carrier-enhanced resistive-pulse sensing. However, hundreds…

Mesoscale and Nanoscale Physics · Physics 2025-10-14 Cengiz J. Khan , Oliver J. Irving , Rand A. Al-Waqfi , Giorgio Ferrari , Tim Albrecht

Neuromorphic computing is poised to further the success of software-based neural networks by utilizing improved customized hardware. However, the translation of neuromorphic algorithms to hardware specifications is a problem that has been…

Emerging Technologies · Computer Science 2022-08-03 Andres E. Lombo , Jesus E. Lares , Matteo Castellani , Chi-Ning Chou , Nancy Lynch , Karl K. Berggren

The integration and parallelization of nanopore sensors are essential for improving the throughput of nanopore measurements. Solid-state nanopores traditionally have been used in isolation, which prevents the realization of their full…

Mesoscale and Nanoscale Physics · Physics 2024-09-23 Peter D. Jones , Michael Mierzejewski

Voltage fluctuations are common disturbances in power grids. Initially, it is necessary to selectively identify individual sources of voltage fluctuations to take actions to minimize the effects of voltage fluctuations. Selective…

Signal Processing · Electrical Eng. & Systems 2023-06-16 Piotr Kuwałek

The nitrogen vacancy (NV) color center in diamond is an enormously important platform for the development of quantum sensors, including for single spin and single molecule NMR. Detection of weak single-spin signals is greatly enhanced by…

Quantum Physics · Physics 2017-05-29 J. E. Lang , J. Casanova , Z. -Y. Wang , M. B. Plenio , T. S. Monteiro

Nanomechanical resonant sensors that are based on detecting and tracking the resonance frequency deviations due to events of interest are being advocated for a variety of applications. All sensor schemes currently in use are subject to a…

Applied Physics · Physics 2021-11-12 Alper Demir

Signals comprised of a stream of short pulses appear in many applications including bio-imaging and radar. The recent finite rate of innovation framework, has paved the way to low rate sampling of such pulses by noticing that only a small…

Information Theory · Computer Science 2015-05-18 Ronen Tur , Yonina C. Eldar , Zvi Friedman

During the dielectric breakdown process of thin solid-state nanopores, the application of high voltages may cause the formation of multi-nanopores on one chip, which number and sizes are important for their applications. Here, simulations…

Chemical Physics · Physics 2024-10-30 Yinghua Qiu , Long Ma , Zhe Liu , Hongwen Zhang , Bowen Ai , Xinman Tu

This paper considers the problem of estimating the delays of a weighted superposition of pulses, called stream of pulses, in a noisy environment. We show that the delays can be estimated using a tractable convex optimization problem with a…

Information Theory · Computer Science 2016-06-29 Tamir Bendory , Avinoam Bar-Zion , Dan Adam , Shai Dekel , Arie Feuer

In pulsed dynamic nuclear polarization (DNP), enhancement of the polarization of bulk nuclei requires the repeated application of a microwave pulse sequence. So far, analysis of a one-time transfer of electron spin polarization to a…

Chemical Physics · Physics 2025-07-24 Shebha Anandhi Jegadeesan , Yujie Zhao , Graham M. Smith , Ilya Kuprov , Guinevere Mathies

Qubit noise spectroscopy is an important tool for the experimental investigation of open quantum systems. However, conventional techniques for noise spectroscopy are time-consuming, because they require measurements of the noise spectral…

Quantum Physics · Physics 2025-06-24 Kaixin Huang , Demitry Farfurnik , Alireza Seif , Mohammad Hafezi , Yi-Kai Liu

One approach to maintaining phase coherence of qubits through dynamical decoupling consists of applying a sequence of Hahn spin-echo pulses. Recent studies have shown that, in certain noise environments, judicious choice of the delay times…

Quantum Physics · Physics 2009-06-24 Hermann Uys , Michael J. Biercuk , John J. Bollinger