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An important problem in the field of bioinformatics is to identify interactive effects among profiled variables for outcome prediction. In this paper, a logistic regression model with pairwise interactions among a set of binary covariates…

Artificial Intelligence · Computer Science 2016-12-30 Easton Li Xu , Xiaoning Qian , Tie Liu , Shuguang Cui

In multivariate statistics, acyclic mixed graphs with directed and bidirected edges are widely used for compact representation of dependence structures that can arise in the presence of hidden (i.e., latent or unobserved) variables. Indeed,…

Statistics Theory · Mathematics 2013-08-20 Christopher J. Fox , Andreas Käufl , Mathias Drton

Under a general structural equation framework for causal inference, we provide a definition of the causal effect of a variable X on another variable Y, and propose an approach to estimate this causal effect via the use of instrumental…

Statistics Theory · Mathematics 2021-04-26 Wing Hung Wong

Graph-based causal discovery methods aim to capture conditional independencies consistent with the observed data and differentiate causal relationships from indirect or induced ones. Successful construction of graphical models of data…

Machine Learning · Statistics 2021-01-08 Boris Hayete , Fred Gruber , Anna Decker , Raymond Yan

The subject of this paper is the elucidation of effects of actions from causal assumptions represented as a directed graph, and statistical knowledge given as a probability distribution. In particular, we are interested in predicting…

Artificial Intelligence · Computer Science 2012-07-02 Ilya Shpitser , Judea Pearl

Causal effect identification considers whether an interventional probability distribution can be uniquely determined without parametric assumptions from measured source distributions and structural knowledge on the generating system. While…

Machine Learning · Statistics 2021-08-30 Santtu Tikka , Antti Hyttinen , Juha Karvanen

In a previous paper [Pearl and Verma, 1991] we presented an algorithm for extracting causal influences from independence information, where a causal influence was defined as the existence of a directed arc in all minimal causal models…

Artificial Intelligence · Computer Science 2013-03-25 Tom S. Verma , Judea Pearl

Randomized experiments are widely used to estimate the causal effects of a proposed treatment in many areas of science, from medicine and healthcare to the physical and biological sciences, from the social sciences to engineering, to public…

Methodology · Statistics 2022-11-30 Christina Lee Yu , Edoardo M Airoldi , Christian Borgs , Jennifer T Chayes

Time-to-event analyses are often plagued by both -- possibly unmeasured -- confounding and competing risks. To deal with the former, the use of instrumental variables for effect estimation is rapidly gaining ground. We show how to make use…

Methodology · Statistics 2018-01-04 Torben Martinussen , Stijn Vansteelandt

In a decision problem, observations are said to be material if they must be taken into account to perform optimally. Decision problems have an underlying (graphical) causal structure, which may sometimes be used to evaluate certain…

Other Statistics · Statistics 2024-07-16 Ryan Carey , Sanghack Lee , Robin J. Evans

Causal models capture cause-effect relations both qualitatively - via the graphical causal structure - and quantitatively - via the model parameters. They offer a powerful framework for analyzing and constructing processes. Here, we…

Quantum Physics · Physics 2025-12-02 Ämin Baumeler , Stefan Wolf

Visualization is a key aspect of communicating the results of any study aiming to estimate causal effects. In studies with time-to-event outcomes, the most popular visualization approach is depicting survival curves stratified by the…

Methodology · Statistics 2023-08-07 Robin Denz , Nina Timmesfeld

What is the ideal regression (if any) for estimating average causal effects? We study this question in the setting of discrete covariates, deriving expressions for the finite-sample variance of various stratification estimators. This…

Methodology · Statistics 2022-09-26 P. Richard Hahn , Andrew Herren

Causal inference is a critical task across fields such as healthcare, economics, and the social sciences. While recent advances in machine learning, especially those based on the deep-learning architectures, have shown potential in…

Machine Learning · Statistics 2024-12-30 Manqing Liu , David R. Bellamy , Andrew L. Beam

Changepoint models enjoy a wide appeal in a variety of disciplines to model the heterogeneity of ordered data. Graphical influence diagnostics to characterize the influence of single observations on changepoint models are, however, lacking.…

Methodology · Statistics 2021-07-23 Ines Wilms , Rebecca Killick , David S. Matteson

We present a comprehensive study of graphical log-linear models for contingency tables. High dimensional contingency tables arise in many areas such as computational biology, collection of survey and census data and others. Analysis of…

Methodology · Statistics 2016-03-15 Niharika Gauraha

The decomposition of the overall effect of a treatment into direct and indirect effects is here investigated with reference to a recursive system of binary random variables. We show how, for the single mediator context, the marginal effect…

Methodology · Statistics 2025-11-14 Martina Raggi , Elena Stanghellini , Marco Doretti

We study the problem of model selection in causal inference, specifically for conditional average treatment effect (CATE) estimation. Unlike machine learning, there is no perfect analogue of cross-validation for model selection as we do not…

Machine Learning · Computer Science 2024-04-30 Divyat Mahajan , Ioannis Mitliagkas , Brady Neal , Vasilis Syrgkanis

This paper proposes a novel graphical model, termed the spatial dependence graph model, which captures the global dependence structure of different events that occur randomly in space. In the spatial dependence graph model, the edge set is…

Methodology · Statistics 2016-07-26 Matthias Eckardt

We introduce a new diagrammatic notation for representing the result of (algebraic) effectful computations. Our notation explicitly separates the effects produced during a computation from the possible values returned, this way simplifying…

Programming Languages · Computer Science 2020-01-13 Ugo Dal Lago , Francesco Gavazzo
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