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Real-world applications may be affected by outlying values. In the model-based clustering literature, several methodologies have been proposed to detect units that deviate from the majority of the data (rowwise outliers) and trim them from…

There are many issues that can cause problems when attempting to infer model parameters from data. Data and models are both imperfect, and as such there are multiple scenarios in which standard methods of inference will lead to misleading…

Computation · Statistics 2024-05-01 Simon L. Cotter

Reliably predicting nuclear properties across the entire chart of isotopes is important for applications ranging from nuclear astrophysics to superheavy science to nuclear technology. To this day, however, all the theoretical models that…

Nuclear Theory · Physics 2025-10-29 Aman Sharma , Nicolas Schunck , Kyle Wendt

In science and engineering, intelligent processing of complex signals such as images, sound or language is often performed by a parameterized hierarchy of nonlinear processing layers, sometimes biologically inspired. Hierarchical systems…

Machine Learning · Computer Science 2012-12-27 Miguel Á. Carreira-Perpiñán , Weiran Wang

Gene-gene interactions are often regarded as playing significant roles in influencing variabilities of complex traits. Although much research has been devoted to this area, to date a comprehensive statistical model that addresses the…

Applications · Statistics 2018-04-18 Durba Bhattacharya , Sourabh Bhattacharya

The conventional way of identifying DNA motifs, solely based on match alignment information, is susceptible to a high number of spurious sites. A novel scoring system has been introduced by taking both match and mismatch alignment…

Quantitative Methods · Quantitative Biology 2014-03-03 Jian-Jun Shu , Kian Yan Yong

Recent advancements in deep learning models for time series forecasting have been significant. These models often leverage fundamental time series properties such as seasonality and non-stationarity, which may suggest an intrinsic link…

Machine Learning · Computer Science 2025-09-09 Fei Wang , Yujie Li , Zezhi Shao , Chengqing Yu , Yisong Fu , Zhulin An , Yongjun Xu , Xueqi Cheng

A hypercomplex representation of DNA is proposed to facilitate comparison of DNA sequences with fuzzy composition. Using hypercomplex number representation, conventional sequence analysis method, such as, dot matrix analysis, dynamic…

Quantitative Methods · Quantitative Biology 2023-08-03 Jian-Jun Shu , Yajing Li

DNA methylation datasets in cancer studies are comprised of measurements on a large number of genomic locations called cytosine-phosphate-guanine (CpG) sites with complex correlation structures. A fundamental goal of these studies is the…

Methodology · Statistics 2023-05-05 Chiyu Gu , Veerabhadran Baladandayuthapani , Subharup Guha

Causal discovery in multi-omic datasets is crucial for understanding the bigger picture of gene regulatory mechanisms, but remains challenging due to high dimensionality, differentiation of direct from indirect relationships, and hidden…

Genomics · Quantitative Biology 2025-05-23 Stephen Asiedu , David Watson

Medical time-series datasets have unique characteristics that make prediction tasks challenging. Most notably, patient trajectories often contain longitudinal variations in their input-output relationships, generally referred to as temporal…

Machine Learning · Computer Science 2021-02-24 Victor D. Bourgin , Ioana Bica , Mihaela van der Schaar

Core-periphery structure is an essential mesoscale feature in complex networks. Previous researches mostly focus on discriminative approaches while in this work, we propose a generative model called masked Bayesian non-negative matrix…

Social and Information Networks · Computer Science 2024-01-17 Zhonghao Wang , Ru Yuan , Jiaye Fu , Ka-Chun Wong , Chengbin Peng

We introduce a Mixture of Raytraced Experts, a stacked Mixture of Experts (MoE) architecture which can dynamically select sequences of experts, producing computational graphs of variable width and depth. Existing MoE architectures generally…

Machine Learning · Computer Science 2025-07-17 Andrea Perin , Giacomo Lagomarsini , Claudio Gallicchio , Giuseppe Nuti

In immunological studies, the characterization of small, functionally distinct cell subsets from blood and tissue is crucial to decipher system level biological changes. An increasing number of studies rely on assays that provide…

Natural image statistics exhibit hierarchical dependencies across multiple scales. Representing such prior knowledge in non-factorial latent tree models can boost performance of image denoising, inpainting, deconvolution or reconstruction…

Computer Vision and Pattern Recognition · Computer Science 2012-07-03 Young Jun Ko , Matthias Seeger

Person Search is designed to jointly solve the problems of Person Detection and Person Re-identification (Re-ID), in which the target person will be located in a large number of uncut images. Over the past few years, Person Search based on…

Computer Vision and Pattern Recognition · Computer Science 2021-04-21 Lequan Chen , Wei Xie , Zhigang Tu , Jinglei Guo , Yaping Tao , Xinming Wang

Understanding how stochastic gene expression is regulated in biological systems using snapshots of single-cell transcripts requires state-of-the-art methods of computational analysis and statistical inference. A Bayesian approach to…

Quantitative Methods · Quantitative Biology 2018-12-10 Yen Ting Lin , Nicolas E. Buchler

The emergence of large-scale Mixture of Experts (MoE) models represents a significant advancement in artificial intelligence, offering enhanced model capacity and computational efficiency through conditional computation. However, deploying…

Machine Learning · Computer Science 2025-01-23 Jiacheng Liu , Peng Tang , Wenfeng Wang , Yuhang Ren , Xiaofeng Hou , Pheng-Ann Heng , Minyi Guo , Chao Li

We study Bayesian estimation of finite mixture models in a general setup where the number of components is unknown and allowed to grow with the sample size. An assumption on growing number of components is a natural one as the degree of…

Statistics Theory · Mathematics 2022-03-18 Ilsang Ohn , Lizhen Lin

Clustering has become a core technology in machine learning, largely due to its application in the field of unsupervised learning, clustering, classification, and density estimation. A frequentist approach exists to hand clustering based on…

Machine Learning · Computer Science 2021-08-27 Jun Lu