English
Related papers

Related papers: MAIES: A Tool for DNA Mixture Analysis

200 papers

High-throughput data analyses are becoming common in biology, communications, economics and sociology. The vast amounts of data are usually represented in the form of matrices and can be considered as knowledge networks. Spectra-based…

Quantitative Methods · Quantitative Biology 2010-01-06 Viet-Anh Nguyen , Zdena Koukolikova-Nicola , Franco Bagnoli , Pietro Lio

Although Bayesian density estimation using discrete mixtures has good performance in modest dimensions, there is a lack of statistical and computational scalability to high-dimensional multivariate cases. To combat the curse of…

Methodology · Statistics 2014-10-29 Ye Wang , Antonio Canale , David Dunson

Computer Vision practitioners must thoroughly understand their model's performance, but conditional evaluation is complex and error-prone. In biometric verification, model performance over continuous covariates---real-number attributes of…

Machine Learning · Computer Science 2020-09-22 Mel McCurrie , Hamish Nicholson , Walter J. Scheirer , Samuel Anthony

The evaluation of a match between the DNA profile of a stain found on a crime scene and that of a suspect (previously identified) involves the use of the unknown parameter $p=(p_1, p_2, ...)$, (the ordered vector which represents the…

Applications · Statistics 2015-09-21 Giulia Cereda

Artificial intelligence (AI) has achieved astonishing successes in many domains, especially with the recent breakthroughs in the development of foundational large models. These large models, leveraging their extensive training data, provide…

Machine Learning · Computer Science 2026-01-27 Siyuan Mu , Sen Lin

This paper uses Gaussian mixture model instead of linear Gaussian model to fit the distribution of every node in Bayesian network. We will explain why and how we use Gaussian mixture models in Bayesian network. Meanwhile we propose a new…

Machine Learning · Statistics 2022-05-17 Yiran Dong , Chuanhou Gao

Mixture of Experts (MoE) models constitute a widely utilized class of ensemble learning approaches in statistics and machine learning, known for their flexibility and computational efficiency. They have become integral components in…

Machine Learning · Statistics 2025-05-26 Tuan Thai , TrungTin Nguyen , Dat Do , Nhat Ho , Christopher Drovandi

A comprehensive artificial intelligence system needs to not only perceive the environment with different `senses' (e.g., seeing and hearing) but also infer the world's conditional (or even causal) relations and corresponding uncertainty.…

Machine Learning · Statistics 2021-01-07 Hao Wang , Dit-Yan Yeung

We introduce an individual claims forecasting framework utilizing Bayesian mixture density networks that can be used for claims analytics tasks such as case reserving and triaging. The proposed approach enables incorporating claims…

Applications · Statistics 2020-03-06 Kevin Kuo

Most existing methods that address out-of-distribution (OOD) generalization for node classification on graphs primarily focus on a specific type of data biases, such as label selection bias or structural bias. However, anticipating the type…

Machine Learning · Computer Science 2023-11-07 Guoxin Chen , Yongqing Wang , Fangda Guo , Qinglang Guo , Jiangli Shao , Huawei Shen , Xueqi Cheng

We propose a MAP Bayesian approach to perform and evaluate a co-clustering of mixed-type data tables. The proposed model infers an optimal segmentation of all variables then performs a co-clustering by minimizing a Bayesian model selection…

Machine Learning · Statistics 2019-02-07 Aichetou Bouchareb , Marc Boullé , Fabrice Rossi , Fabrice Clérot

We present methods for inference about relationships between contributors to a DNA mixture and other individuals of known genotype: a basic example would be testing whether a contributor to a mixture is the father of a child of known…

Applications · Statistics 2017-01-30 Peter J. Green , Julia Mortera

This work is motivated by an application in neuroscience, in particular by the study of the (dys)functioning of a protein called Tau. The objective is to establish a classification of intensity profiles, according to the presence or absence…

Methodology · Statistics 2025-06-13 Vincent Brault , Emilie Lebarbier , Amélie Rosier , Virginie Stoppin-Mellet

Finite-context modeling is a powerful tool for compressing and hence for representing DNA sequences. We describe an algorithm to detect genomic regularities, within a blind discovery strategy. The algorithm uses information profiles built…

Genomics · Quantitative Biology 2014-01-21 Armando J. Pinho , Diogo Pratas , Paulo J. S. G. Ferreira

The advancement and adoption of Artificial Intelligence (AI) models across diverse domains have transformed the way we interact with technology. However, it is essential to recognize that while AI models have introduced remarkable…

Cryptography and Security · Computer Science 2025-05-07 Hema Karnam Surendrababu , Nithin Nagaraj

We develop a novel peak detection algorithm for the analysis of comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC$\times$GC-TOF MS) data using normal-exponential-Bernoulli (NEB) and mixture probability…

Applications · Statistics 2014-08-04 Seongho Kim , Ming Ouyang , Jaesik Jeong , Changyu Shen , Xiang Zhang

Following the discovery of the brightest high-energy neutrino sources in the sky, the further detection of fainter sources is more challenging. A natural solution is to combine fainter source candidates, and instead of individual…

High Energy Astrophysical Phenomena · Physics 2025-06-03 I. Bartos , M. Ackermann , M. Kowalski

Background: Many mathematical models have now been employed across every area of systems biology. These models increasingly involve large numbers of unknown parameters, have complex structure which can result in substantial evaluation time…

Molecular Networks · Quantitative Biology 2018-01-15 Ian Vernon , Junli Liu , Michael Goldstein , James Rowe , Jen Topping , Keith Lindsey

Seemingly unrelated linear regression models are introduced in which the distribution of the errors is a finite mixture of Gaussian components. Identifiability conditions are provided. The score vector and the Hessian matrix are derived.…

Methodology · Statistics 2014-03-18 Giuliano Galimberti , Elena Scardovi , Gabriele Soffritti

Understanding and interpreting how machine learning (ML) models make decisions have been a big challenge. While recent research has proposed various technical approaches to provide some clues as to how an ML model makes individual…

Machine Learning · Computer Science 2018-11-09 Wenbo Guo , Sui Huang , Yunzhe Tao , Xinyu Xing , Lin Lin