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We analyze large, multi-dimensional, sparse counting data sets, finding unsupervised groups to provide unique insights into genetic data. We create gene and biological pathway groups based on patients' variants to find common risk factors…

Machine Learning · Computer Science 2025-09-01 Adam Sandler , Diego Klabjan , Yuan Luo

The collective risk model (CRM) for frequency and severity is an important tool for retail insurance ratemaking, macro-level catastrophic risk forecasting, as well as operational risk in banking regulation. This model, which is initially…

Applications · Statistics 2021-10-20 Jae Youn Ahn , Himchan Jeong , Yang Lu

The preponderance of large-scale healthcare databases provide abundant opportunities for comparative effectiveness research. Evidence necessary to making informed treatment decisions often relies on comparing effectiveness of multiple…

Methodology · Statistics 2020-10-06 Liangyuan Hu , Chenyang Gu

In this work, we offer a thorough analytical investigation into the role of shared hyperparameters in a hierarchical Bayesian model, examining their impact on information borrowing and posterior inference. Our approach is rooted in a…

Methodology · Statistics 2025-09-23 Prasenjit Ghosh , Anirban Bhattacharya , Debdeep Pati

There is currently a renewed interest in the Bayesian predictive approach to statistics. This paper offers a review on foundational concepts and focuses on predictive modeling, which by directly reasoning on prediction, bypasses inferential…

Statistics Theory · Mathematics 2024-11-22 Sandra Fortini , Sonia Petrone

Bayesian inference and the use of posterior or posterior predictive probabilities for decision making have become increasingly popular in clinical trials. The current practice in Bayesian clinical trials relies on a hybrid…

Methodology · Statistics 2024-04-30 Shirin Golchi , James Willard

Hierarchical Bayesian methods enable information sharing across multiple related regression problems. While standard practice is to model regression parameters (effects) as (1) exchangeable across datasets and (2) correlated to differing…

Methodology · Statistics 2021-07-15 Brian L. Trippe , Hilary K. Finucane , Tamara Broderick

Bayesian analysis is a framework for parameter estimation that applies even in uncertainty regimes where the commonly used local (frequentist) analysis based on the Cram\'er-Rao bound is not well defined. In particular, it applies when no…

Quantum Physics · Physics 2021-03-17 Simon Morelli , Ayaka Usui , Elizabeth Agudelo , Nicolai Friis

Individual-level effectiveness and healthcare resource use (HRU) data are routinely collected in trial-based economic evaluations. While effectiveness is often expressed in terms of utility scores derived from some health-related quality of…

Methodology · Statistics 2024-07-31 Andrea Gabrio

We propose a probabilistic modeling framework for learning the dynamic patterns in the collective behaviors of social agents and developing profiles for different behavioral groups, using data collected from multiple information sources.…

Machine Learning · Statistics 2016-06-28 Lin Li , Ananthram Swami , Anna Scaglione

We consider a dictionary learning problem whose objective is to design a dictionary such that the signals admits a sparse or an approximate sparse representation over the learned dictionary. Such a problem finds a variety of applications…

Machine Learning · Computer Science 2015-03-10 Linxiao Yang , Jun Fang , Hong Cheng , Hongbin Li

Air pollution remains a major environmental risk factor that is often associated with adverse health outcomes. However, quantifying and evaluating its effects on human health is challenging due to the complex nature of exposure data. Recent…

Methodology · Statistics 2025-06-02 Soumyakanti Pan , Sudipto Banerjee

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

Machine Learning · Computer Science 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

Cardiovascular disease is the number one cause of death all over the world. Data mining can help to retrieve valuable knowledge from available data from the health sector. It helps to train a model to predict patients' health which will be…

Machine Learning · Computer Science 2020-12-18 Mistura Muibideen , Rajesh Prasad

We combine Bayesian prediction and weighted inference as a unified approach to survey inference. The general principles of Bayesian analysis imply that models for survey outcomes should be conditional on all variables that affect the…

Methodology · Statistics 2020-06-24 Yajuan Si , Rob Trangucci , Jonah Sol Gabry , Andrew Gelman

Traditional epidemic detection algorithms make decisions using only local information. We propose a novel approach that explicitly models spatial information fusion from several metapopulations. Our method also takes into account…

Computation · Statistics 2015-09-15 Michael Ludkovski , Katherine Shatskikh

A critical step in data analysis for many different types of experiments is the identification of features with theoretically defined shapes in N-dimensional datasets; examples of this process include finding peaks in multi-dimensional…

Data Analysis, Statistics and Probability · Physics 2022-08-25 Korak Kumar Ray , Anjali R. Verma , Ruben L. Gonzalez , Colin D. Kinz-Thompson

We propose a multiple cohort expansion (MUCE) approach as a design or analysis method for phase 1b multiple expansion cohort trials, which are novel first-in-human studies conducted following phase 1a dose escalation. The MUCE design is…

Methodology · Statistics 2025-05-21 Jiaying Lyu , Tianjian Zhou , Shijie Yuan , Wentian Guo , Yuan Ji

Raking is widely used in categorical data modeling and survey practice but faced with methodological and computational challenges. We develop a Bayesian paradigm for raking by incorporating the marginal constraints as a prior distribution…

Methodology · Statistics 2020-06-24 Yajuan Si , Peigen Zhou

This study presents a machine learning-based framework for heart disease prediction using the heart-disease dataset, comprising 303 samples with 14 features. The methodology involves data preprocessing, model training, and evaluation using…

Machine Learning · Computer Science 2025-05-16 Ali Azimi Lamir , Shiva Razzagzadeh , Zeynab Rezaei