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Multiple sequence alignment (MSA) is a ubiquitous problem in computational biology. Although it is NP-hard to find an optimal solution for an arbitrary number of sequences, due to the importance of this problem researchers are trying to…

Artificial Intelligence · Computer Science 2011-09-29 S. Schroedl

Recent work reported that simple Bayesian optimization (BO) methods perform well for high-dimensional real-world tasks, seemingly contradicting prior work and tribal knowledge. This paper investigates why. We identify underlying challenges…

Machine Learning · Computer Science 2026-05-15 Leonard Papenmeier , Matthias Poloczek , Luigi Nardi

We present a general method for obtaining strong bounds for discrete optimization problems that is based on a concept of branching duality. It can be applied when no useful integer programming model is available, and we illustrate this with…

Data Structures and Algorithms · Computer Science 2019-08-22 J. G. Benade , J. N. Hooker

Mixed integer linear programs are commonly solved by Branch and Bound algorithms. A key factor of the efficiency of the most successful commercial solvers is their fine-tuned heuristics. In this paper, we leverage patterns in real-world…

Machine Learning · Computer Science 2020-12-02 Marc Etheve , Zacharie Alès , Côme Bissuel , Olivier Juan , Safia Kedad-Sidhoum

It was recently shown that the problem of decoding messages transmitted through a noisy channel can be formulated as a belief updating task over a probabilistic network [McEliece]. Moreover, it was observed that iterative application of the…

Artificial Intelligence · Computer Science 2013-02-01 Irina Rish , Kalev Kask , Rina Dechter

Probabilistic verification problems of neural networks are concerned with formally analysing the output distribution of a neural network under a probability distribution of the inputs. Examples of probabilistic verification problems include…

Machine Learning · Computer Science 2025-07-11 David Boetius , Stefan Leue , Tobias Sutter

Bayesian optimization (BO) is a successful methodology to optimize black-box functions that are expensive to evaluate. While traditional methods optimize each black-box function in isolation, there has been recent interest in speeding up BO…

Machine Learning · Statistics 2019-09-30 Valerio Perrone , Huibin Shen , Matthias Seeger , Cedric Archambeau , Rodolphe Jenatton

Bayesian optimization (BO) is among the most effective and widely-used blackbox optimization methods. BO proposes solutions according to an explore-exploit trade-off criterion encoded in an acquisition function, many of which are computed…

Machine Learning · Computer Science 2021-02-19 Louis C. Tiao , Aaron Klein , Matthias Seeger , Edwin V. Bonilla , Cedric Archambeau , Fabio Ramos

The performance of acquisition functions for Bayesian optimisation to locate the global optimum of continuous functions is investigated in terms of the Pareto front between exploration and exploitation. We show that Expected Improvement…

Machine Learning · Computer Science 2021-04-29 George De Ath , Richard M. Everson , Alma A. M. Rahat , Jonathan E. Fieldsend

In recent years, deep neural networks have had great success in machine learning and pattern recognition. Architecture size for a neural network contributes significantly to the success of any neural network. In this study, we optimize the…

Machine Learning · Computer Science 2021-01-19 Yigit Alparslan , Ethan Jacob Moyer , Isamu Mclean Isozaki , Daniel Schwartz , Adam Dunlop , Shesh Dave , Edward Kim

We present the Branch-and-Bound Performance Estimation Programming (BnB-PEP), a unified methodology for constructing optimal first-order methods for convex and nonconvex optimization. BnB-PEP poses the problem of finding the optimal…

Optimization and Control · Mathematics 2023-06-09 Shuvomoy Das Gupta , Bart P. G. Van Parys , Ernest K. Ryu

In this research work, probabilistic decision-making approaches are studied, e.g. Bayesian and Boltzmann strategies, along with various deterministic exploration strategies, e.g. greedy, epsilon-Greedy and random approaches. In this…

Artificial Intelligence · Computer Science 2019-06-04 Arsh Javed Rehman , Pradeep Tomar

We study prioritized planning for Multi-Agent Path Finding (MAPF). Existing prioritized MAPF algorithms depend on rule-of-thumb heuristics and random assignment to determine a fixed total priority ordering of all agents a priori. We instead…

Artificial Intelligence · Computer Science 2018-12-18 Hang Ma , Daniel Harabor , Peter J. Stuckey , Jiaoyang Li , Sven Koenig

Experiments in research on memory, language, and in other areas of cognitive science are increasingly being analyzed using Bayesian methods. This has been facilitated by the development of probabilistic programming languages such as Stan,…

Methodology · Statistics 2020-03-02 Daniel J. Schad , Michael Betancourt , Shravan Vasishth

Researchers constantly strive to explore larger and more complex search spaces in various scientific studies and physical experiments. However, such investigations often involve sophisticated simulators or time-consuming experiments that…

Machine Learning · Computer Science 2023-08-21 Shikhar Tuli , Niraj K. Jha

Despite the great interest in the bandit problem, designing efficient algorithms for complex models remains challenging, as there is typically no analytical way to quantify uncertainty. In this paper, we propose Multiplier Bootstrap-based…

Machine Learning · Computer Science 2023-02-06 Runzhe Wan , Haoyu Wei , Branislav Kveton , Rui Song

Automatic optimization for tensor programs becomes increasingly important as we deploy deep learning in various environments, and efficient optimization relies on a rich search space and effective search. Most existing efforts adopt a…

Machine Learning · Computer Science 2022-10-11 Junru Shao , Xiyou Zhou , Siyuan Feng , Bohan Hou , Ruihang Lai , Hongyi Jin , Wuwei Lin , Masahiro Masuda , Cody Hao Yu , Tianqi Chen

We design a space-efficient algorithm for performing depth-first search traversal(DFS) of a graph in $O(m+n\log^* n)$ time using $O(n)$ bits of space. While a normal DFS algorithm results in a DFS-tree (in case the graph is connected), our…

Data Structures and Algorithms · Computer Science 2018-10-18 Jayesh Choudhari , Manoj Gupta , Shivdutt Sharma

Information theoretic active learning has been widely studied for probabilistic models. For simple regression an optimal myopic policy is easily tractable. However, for other tasks and with more complex models, such as classification with…

Machine Learning · Statistics 2011-12-30 Neil Houlsby , Ferenc Huszár , Zoubin Ghahramani , Máté Lengyel

Many approaches to program synthesis perform a combinatorial search within a large space of programs to find one that satisfies a given specification. To tame the search space blowup, previous works introduced probabilistic and neural…

Machine Learning · Computer Science 2024-12-24 Théo Matricon , Nathanaël Fijalkow , Guillaume Lagarde