English
Related papers

Related papers: Feature extraction in protein sequences classifica…

200 papers

Feature Selection techniques aim at finding a relevant subset of features that perform equally or better than the original set of features at explaining the behavior of data. Typically, features are extracted from feature ranking or subset…

Machine Learning · Computer Science 2024-11-05 Jesus S. Aguilar-Ruiz

Feature selection is frequently used as a pre-processing step to machine learning. It is a process of choosing a subset of original features so that the feature space is optimally reduced according to a certain evaluation criterion. The…

Computer Vision and Pattern Recognition · Computer Science 2014-01-07 Vijendra Singh , Shivani Pathak

The capability of accurate prediction of protein functions and properties is essential in the biotechnology industry, e.g. drug development and artificial protein synthesis, etc. The main challenges of protein function prediction are the…

Quantitative Methods · Quantitative Biology 2021-12-02 Wei-Cheng Tseng , Po-Han Chi , Jia-Hua Wu , Min Sun

We study the problem of linear feature selection when features are highly correlated. Such settings pose two fundamental challenges. First, how should model similarity be defined? Simply counting features in common can be misleading: two…

Methodology · Statistics 2026-03-24 Xiaozhu Zhang , Jacob Bien , Armeen Taeb

The classification of DNA sequences is a key research area in bioinformatics as it enables researchers to conduct genomic analysis and detect possible diseases. In this paper, three state-of-the-art algorithms, namely Convolutional Neural…

Other Quantitative Biology · Quantitative Biology 2020-11-03 Xiangxie Zhang , Ben Beinke , Berlian Al Kindhi , Marco Wiering

Feature selection is an important task in many problems occurring in pattern recognition, bioinformatics, machine learning and data mining applications. The feature selection approach enables us to reduce the computation burden and the…

Machine Learning · Computer Science 2016-08-30 Hadi Zare , Mojtaba Niazi

Event logs are widely used for anomaly detection and prediction in complex systems. Existing log-based anomaly detection methods usually consist of four main steps: log collection, log parsing, feature extraction, and anomaly detection,…

Machine Learning · Computer Science 2022-12-20 Zhong Li , Matthijs van Leeuwen

The purpose of feature extraction on convolutional neural networks is to reuse deep representations learnt for a pre-trained model to solve a new, potentially unrelated problem. However, raw feature extraction from all layers is unfeasible…

Neural and Evolutionary Computing · Computer Science 2019-11-11 Victor Gimenez-Abalos , Armand Vilalta , Dario Garcia-Gasulla , Jesus Labarta , Eduard Ayguadé

Network motif provides a way to uncover the basic building blocks of most complex networks. This task usually demands high computer processing, specially for motif with 5 or more vertices. This paper presents an extended methodology with…

Data Structures and Algorithms · Computer Science 2018-04-27 Luis A. A. Meira , Vinícius R. Máximo , Alvaro L. Fazenda , Arlindo F. da Conceição

Protein function does not solely depend on structure but often relies on dynamical transitions between distinct conformations. Despite this fact, our ability to characterize or predict protein dynamics is substantially less developed…

Statistical Mechanics · Physics 2026-05-08 Michael A. Sauer , Souvik Mondal , Brandon Neff , Sthitadhi Maiti , Matthias Heyden

Advances in machine learning technologies have led to increasingly powerful models in particular in the context of big data. Yet, many application scenarios demand for robustly interpretable models rather than optimum model accuracy; as an…

Machine Learning · Computer Science 2020-05-07 Lukas Pfannschmidt , Jonathan Jakob , Fabian Hinder , Michael Biehl , Peter Tino , Barbara Hammer

Applying machine learning to biological sequences - DNA, RNA and protein - has enormous potential to advance human health, environmental sustainability, and fundamental biological understanding. However, many existing machine learning…

Machine Learning · Statistics 2023-04-11 Alan Nawzad Amin , Eli Nathan Weinstein , Debora Susan Marks

Data mining techniques have been used by researchers for analyzing protein sequences. In protein analysis, especially in protein sequence classification, selection of feature is most important. Popular protein sequence classification…

Databases · Computer Science 2012-11-22 Suprativ Saha , Rituparna Chaki

Visibility algorithms transform time series into graphs and encode dynamical information in their topology, paving the way for graph-theoretical time series analysis as well as building a bridge between nonlinear dynamics and network…

Data Analysis, Statistics and Probability · Physics 2016-05-11 Jacopo Iacovacci , Lucas Lacasa

Feature selection is generally used as one of the most important preprocessing techniques in machine learning, as it helps to reduce the dimensionality of data and assists researchers and practitioners in understanding data. Thereby, by…

Machine Learning · Computer Science 2021-04-26 Yiwen Liao , Raphaël Latty , Bin Yang

Enzymes and proteins are live driven biochemicals, which has a dramatic impact over the environment, in which it is active. So, therefore, it is highly looked-for to build such a robust and highly accurate automatic and computational model…

Biomolecules · Quantitative Biology 2021-01-11 Zaheer Ullah Khan , Dechang Pi , Izhar Ahmed Khan , Asif Nawaz , Jamil Ahmad , Mushtaq Hussain

The motif-scaffolding problem is a central task in computational protein design: Given the coordinates of atoms in a geometry chosen to confer a desired biochemical function (a motif), the task is to identify diverse protein structures…

Machine Learning · Computer Science 2025-02-20 Zhuoqi Zheng , Bo Zhang , Kieran Didi , Kevin K. Yang , Jason Yim , Joseph L. Watson , Hai-Feng Chen , Brian L. Trippe

Background: DNA, RNA, and protein sequence motifs can be recognition sites for biological functions such as regulation, DNA base modification, and molecular binding in general. The gain and loss of such motifs can carry important…

Genomics · Quantitative Biology 2022-10-19 Afif Elghraoui , Faramarz Valafar

Feature selection is a preprocessing step which plays a crucial role in the domain of machine learning and data mining. Feature selection methods have been shown to be effctive in removing redundant and irrelevant features, improving the…

Machine Learning · Computer Science 2021-06-01 Xiongshi Deng , Min Li , Lei Wang , Qikang Wan

Incorporating feature selection into a classification or regression method often carries a number of advantages. In this paper we formalize feature selection specifically from a discriminative perspective of improving…

Machine Learning · Computer Science 2013-01-18 Tony S. Jebara , Tommi S. Jaakkola