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Synaptic connections in neuronal circuits are modulated by pre- and post-synaptic spiking activity. Heuristic models of this process of synaptic plasticity can provide excellent fits to results from in-vitro experiments in which pre- and…

Neurons and Cognition · Quantitative Biology 2022-07-14 Federico Devalle , Alex Roxin

We investigate the growth of a branched actin network under load. Using a combination of simulations and theory, we show that the network adapts to the load and exhibits two regimes: a finite velocity at low stress, followed by a power-law…

Soft Condensed Matter · Physics 2025-01-10 Magid Badaoui , Serge Dmitrieff

We propose a statistical model of a large random network with high connectivity in order to describe the behavior of {\it E.\,coli} cells after exposure to acute stress. The building blocks of this network are feedback cycles typical of the…

Disordered Systems and Neural Networks · Physics 2022-02-22 S. Reich , S. Maoz , Y. Kaplan , H. Rappeport , N. Q. Balaban , O. Agam

We study the effects of uniform time delays on the extreme fluctuations in stochastic synchronization and coordination problems with linear couplings in complex networks. We obtain the average size of the fluctuations at the nodes from the…

Statistical Mechanics · Physics 2015-12-15 D. Hunt , F. Molnar , B. K. Szymanski , G. Korniss

Recent advances in designing meta-materials have demonstrated that global mechanical properties of disordered spring networks can be tuned by selectively modifying only a small subset of bonds. Here, using a computationally-efficient…

It has been recently shown that randomly charged surfaces can exhibit long range electrostatic interactions even when they are net neutral. These forces depend on the specific realization of charge disorder and thus exhibit sample to sample…

Soft Condensed Matter · Physics 2011-12-30 David S. Dean , Ali Naji , Rudolf Podgornik

Active dynamic processes of cells are largely driven by the cytoskeleton, a complex and adaptable semiflexible polymer network, motorized by mechanoenzymes. Small dimensions, confined geome- tries and hierarchical structures make it…

Biological Physics · Physics 2017-08-23 Jannes Gladrow , Chase P. Broedersz , Christoph F. Schmidt

The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to enhance human performance. Despite the growing interest in brain stimulation as a form of neuromodulation,…

Neurons and Cognition · Quantitative Biology 2016-01-07 Sarah Feldt Muldoon , Fabio Pasqualetti , Shi Gu , Matthew Cieslak , Scott T. Grafton , Jean M. Vettel , Danielle S. Bassett

We construct and analyze a model for a disordered linear spring network with anisotropy. The modeling is motivated by, for example, granular systems, nematic elastomers, and ultimately cytoskeletal networks exhibiting some underlying…

Soft Condensed Matter · Physics 2015-06-22 T. Zhang , J. M. Schwarz , Moumita Das

The most profound effect of disorder on the elastic response of solids is the nonaffinity of local displacements whereby the atoms (particles, network junctions) do not simply follow the macroscopic strain, as they do in perfect crystals,…

Soft Condensed Matter · Physics 2012-01-12 Alessio Zaccone , Jamie R. Blundell , Eugene M. Terentjev

Mesoscopic models of finite-size neuronal populations are crucial to understand the dynamics of neural networks in the brain, especially their fluctuations and response to stimuli. However, current theories to derive such models are based…

Neurons and Cognition · Quantitative Biology 2026-01-26 Nils E. Greven , Jonas Ranft , Tilo Schwalger

Motivated by recent experiments showing that stiff biopolymer gels exhibit highly unusual negative normal elastic stresses, we develop a computational model for stiff polymer networks subject to large strains. In all cases, we find that…

Soft Condensed Matter · Physics 2009-11-13 Enrico Conti , F. C. MacKintosh

In multi-class communication networks, traffic surges due to one class of users can significantly degrade the performance for other classes. During these transient periods, it is thus of crucial importance to implement priority mechanisms…

Performance · Computer Science 2011-12-12 Mathieu Feuillet , Matthieu Jonckheere , Balakrishna J. Prabhu

Disordered spring networks can exhibit rigidity transitions, due to either the removal of materials in over-constrained networks or the application of strain in under-constrained ones. While an effective medium theory (EMT) exists for the…

Soft Condensed Matter · Physics 2022-04-04 Ojan Khatib Damavandi , M. Lisa Manning , J. M. Schwarz

We study the onset of spin superfluidity, namely coherent spin transport mediated by a topological spin texture, in frustrated exchange-dominated magnetic systems, engendered by an external magnetic field. We show that for typical device…

Mesoscale and Nanoscale Physics · Physics 2021-05-26 Ricardo Zarzuela , Daniel Hill , Jairo Sinova , Yaroslav Tserkovnyak

The human brain exhibits a complex structure made of scale-free highly connected modules loosely interconnected by weaker links to form a small-world network. These features appear in healthy patients whereas neurological diseases often…

Neurons and Cognition · Quantitative Biology 2014-03-26 Roberta Russo , Hans J Herrmann , Lucilla de Arcangelis

In the experiments on stress-induced phase transitions in SMA strips, several interesting instability phenomena have been observed, including a necking-type instability, a shear-type instability and an orientation instability. By using the…

Classical Physics · Physics 2009-10-15 Hui-Hui Dai , Zongxi Cai

We study the micromechanics of collagen-I gel with the goal of bridging the gap between theory and experiment in the study of biopolymer networks. Three-dimensional images of fluorescently labeled collagen are obtained by confocal…

Soft Condensed Matter · Physics 2009-09-29 Andrew M. Stein , David A. Vader , David A. Weitz , Leonard M. Sander

We generalize the technique of smoothed analysis to distributed algorithms in dynamic network models. Whereas standard smoothed analysis studies the impact of small random perturbations of input values on algorithm performance metrics,…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-08-17 Michael Dinitz , Jeremy T. Fineman , Seth Gilbert , Calvin Newport

We investigate the relationship of resting-state fMRI functional connectivity estimated over long periods of time with time-varying functional connectivity estimated over shorter time intervals. We show that using Pearson's correlation to…

Neurons and Cognition · Quantitative Biology 2016-09-08 Richard F. Betzel , Makoto Fukushima , Ye He , Xi-Nian Zuo , Olaf Sporns