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Diabetic retinopathy (DR) grading from fundus images has attracted increasing interest in both academic and industrial communities. Most convolutional neural network (CNN) based algorithms treat DR grading as a classification task via…

Computer Vision and Pattern Recognition · Computer Science 2021-03-19 Yehui Yang , Fangxin Shang , Binghong Wu , Dalu Yang , Lei Wang , Yanwu Xu , Wensheng Zhang , Tianzhu Zhang

Previous approaches using deep learning algorithms to classify glaucomatous damage on fundus photographs have been limited by the requirement for human labeling of a reference training set. We propose a new approach using spectral-domain…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Felipe A. Medeiros , Alessandro A. Jammal , Atalie C. Thompson

This paper investigates lung nodule classification by using deep neural networks (DNNs). Hyperparameter optimization in DNNs is a computationally expensive problem, where evaluating a hyperparameter configuration may take several hours or…

Machine Learning · Computer Science 2019-01-03 Miao Zhang , Huiqi Li , Juan Lyu , Sai Ho Ling , Steven Su

Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

In this work the complete L-emission spectrum of gadolinium with respect to line energies, natural line widths, and relative transition probabilities was investigated using monochromatized synchrotron radiation. The measurements were…

Retinal diseases can cause irreversible vision loss in both eyes if not diagnosed and treated early. Since retinal diseases are so complicated, retinal imaging is likely to show two or more abnormalities. Current deep learning techniques…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Tariq M Khan , Shahzaib Iqbal , Syed S. Naqvi , Imran Razzak , Erik Meijering

Purpose: This paper describes a new method to apply deep-learning algorithms for automatic segmentation of radiosensitive organs from 3D tomographic CT images before computing organ doses using a GPU-based Monte Carlo code. Methods: A deep…

Medical Physics · Physics 2020-09-09 Zhao Peng , Xi Fang , Pingkun Yan , Hongming Shan , Tianyu Liu , Xi Pei , Ge Wang , Bob Liu , Mannudeep K. Kalra , X. George Xu

Deep Brain Stimulation (DBS) is one of the most successful methods to diminish late-stage Parkinson's Disease (PD) symptoms. It is a delicate surgical procedure which requires detailed pre-surgical patient's study. High-field Magnetic…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Tomás Lima , Igor Varga , Eduard Bakštein , Daniel Novák , Victor Alves

We demonstrate ultra-sharp (${\lesssim}\,10\text{ nm}$) lateral $p\text{-}n$ junctions in graphene using electronic transport, scanning tunneling microscopy, and first principles calculations. The $p\text{-}n$ junction lies at the boundary…

We confine a Cs thermal vapor in the interstitial regions of a glass opal. We perform linear reflection spectroscopy on a cell whose window is covered with a thin film (10 or 20 layers) of ~ 1000 nm (or 400 nm) diameter glass spheres, we…

Atomic Physics · Physics 2015-06-16 Philippe Ballin , Elias Moufarej , Isabelle Maurin , Athanasios Laliotis , Daniel Bloch

Tuberculosis (TB) is a chronic lung disease that occurs due to bacterial infection and is one of the top 10 leading causes of death. Accurate and early detection of TB is very important, otherwise, it could be life-threatening. In this…

Purpose - To develop and validate a deep learning (DL) framework for the detection and quantification of drusen and reticular pseudodrusen (RPD) on optical coherence tomography scans. Design - Development and validation of deep learning…

According to current anatomy, the arteries and veins do not have threadlike structures running inside the vessels. Despite such prevailing knowledge here we report on observation of a novel structure inside the blood vessels of rats and…

The inner structure of AGNs is expected to change below a certain luminosity limit. The big blue bump, footprint of the accretion disk, is absent for the majority of low-luminosity AGNs (LLAGNs). Moreover, recent simulations suggest that…

Cosmology and Nongalactic Astrophysics · Physics 2015-06-05 J. A. Fernández-Ontiveros , M. A. Prieto , J. A. Acosta-Pulido , M. Montes

We report the results of 3D spectroscopic observations of Mrk 493 (NLS1 galaxy) with the integral-field spectrograph MPFS of the SAO RAS 6-m telescope. The difference in the slope of the optical continuum emission intensity across the…

Astrophysics · Physics 2009-11-13 L. C. Popovic , A. A. Smirnova , J. Kovacevic , A. V Moiseev , V. L. Afanasiev

Objective: Research on eye lens dosimetry for radiation workers has increased after the 2012 ICRP118 update on eye lens dose limits. However, corneal dosimetry remains underexplored due to historical focus and measurement challenges. This…

Medical Physics · Physics 2025-09-26 Zahra Akbari Khanaposhtani , Hossein Rajabi

Objective: Large irradiated volumes are a major contributor to severe side-effects in patients with head and neck cancer undergoing curatively intended radiotherapy. We propose a data-driven approach for defining the elective clinical…

Ultrasound-based risk stratification of thyroid nodules is a critical clinical task, but it suffers from high inter-observer variability. While many deep learning (DL) models function as "black boxes," we propose a fully automated,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Omar Abdelrazik , Mohamed Elsayed , Noorul Wahab , Nasir Rajpoot , Adam Shephard

Accurate segmentation of the blood vessels of the retina is an important step in clinical diagnosis of ophthalmic diseases. Many deep learning frameworks have come up for retinal blood vessels segmentation tasks. However, the complex…

Image and Video Processing · Electrical Eng. & Systems 2022-04-08 Ting Zhang , Jun Li , Yi Zhao , Nan Chen , Han Zhou , Hongtao Xu , Zihao Guan , Changcai Yang , Lanyan Xue , Riqing Chen , Lifang Wei