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The epigenetic pathway of a cell as it differentiates from a stem cell state to a mature lineage-committed one has been historically understood in terms of Waddington's landscape, consisting of hills and valleys. The smooth top and…

Cell Behavior · Quantitative Biology 2013-06-12 Mithun K. Mitra , Paul R. Taylor , Chris J. Hutchison , T. C. B. McLeish , Buddhapriya Chakrabarti

The paper proposes two dynamical systems based on the generalized Lotka-Volterra model of three excitable elements interacting through excitatory couplings. It is shown that for some values of the coupling parameters in the phase space of…

Chaotic Dynamics · Physics 2023-12-11 A. G. Korotkov , S. Y. Zagrebin , G. V. Osipov

Many processes in nature seem to be entirely controlled by transition rates and the corresponding statistical dynamics. Some of them are in essence quantum, like the decay of excited states, the tunneling through barriers or the decay of…

Quantum Physics · Physics 2007-05-23 Jochen Gemmer , Mathias Michel

We investigate in detail a recent model of colliding mobile agents [Phys. Rev. Lett.~96, 088702], used as an alternative approach to construct evolving networks of interactions formed by the collisions governed by suitable dynamical rules.…

Physics and Society · Physics 2013-01-01 Marta C. González , Pedro G. Lind , Hans J. Herrmann

It is a fundamental problem to characterize the nonequilibrium processes. For a slowly moving one-dimensional potential, we explore the quasi adiabatic dynamics of the initial energy eigenstates for a confined quantum system interacting…

Statistical Mechanics · Physics 2017-10-11 Takaaki Monnai

The concept of fitness is introduced, and a simple derivation of the Fundamental Theorem of Natural Selection (which states that the average fitness of a population increases if its variance is nonzero) is given. After a short discussion of…

Condensed Matter · Physics 2008-02-03 Luca Peliti

In Mean Field Games of Controls, the dynamics of the single agent is influenced not only by the distribution of the agents, as in the classical theory, but also by the distribution of their optimal strategies. In this paper, we study…

Analysis of PDEs · Mathematics 2023-02-01 Fabio Camilli , Claudio Marchi

The empirical-phenomenological quasi-deuteron photofission description is theoretically justified within the semiclassical, intermediate statistics model. The transmutational fermion (nucleon) - boson (quasi-deuteron) potential plays an…

Nuclear Theory · Physics 2015-06-26 G. Kaniadakis , A. Lavagno , P. Quarati

Quantifying stochastic processes is essential to understand many natural phenomena, particularly in biology, including cell-fate decision in developmental processes as well as genesis and progression of cancers. While various attempts have…

Statistical Mechanics · Physics 2017-06-28 Ying Tang , Ruoshi Yuan , Gaowei Wang , Xiaomei Zhu , Ping Ao

We construct a stochastic dynamical systems theory in which sustainability is a structural boundary property of a fully coupled Earth--Human--Production system. Each subsystem is modelled as a vector-valued process governed by stochastic…

Theoretical Economics · Economics 2026-03-02 Claudio Pirrone , Stefano Fricano , Gioacchino Fazio

The relation between saddle points of the potential of a classical many-particle system and the analyticity properties of its thermodynamic functions is studied. For finite systems, each saddle point is found to cause a nonanalyticity in…

Statistical Mechanics · Physics 2011-11-09 Michael Kastner , Oliver Schnetz , Steffen Schreiber

Quasistatic evolutions of critical points of time-dependent energies exhibit piecewise smooth behavior, making them useful for modeling continuum mechanics phenomena like elastic-plasticity and fracture. Traditionally, such evolutions have…

Optimization and Control · Mathematics 2026-01-09 Stefano Almi , Massimo Fornasier , Jona Klemenc , Alessandro Scagliotti

A two-dimensional lattice system of non-interacting electrons in a homogeneous magnetic field with half a flux quantum per plaquette and a random potential is considered. For the large scale behavior a supersymmetric theory with collective…

Mesoscale and Nanoscale Physics · Physics 2009-10-28 K. Ziegler

A branching random walk in presence of an absorbing wall moving at a constant velocity $v$ undergoes a phase transition as the velocity $v$ of the wall varies. Below the critical velocity $v_c$, the population has a non-zero survival…

Statistical Mechanics · Physics 2008-02-12 Damien Simon , Bernard Derrida

We study in detail a recently proposed simple discrete model for evolution on smooth landscapes. An asymptotic solution of this model for long times is constructed. We find that the dynamics of the population are governed by correlation…

Condensed Matter · Physics 2009-10-28 David A. Kessler , Herbert Levine , Douglas Ridgway , Lev Tsimring

Cells can often choose among several stably heritable phenotypes. Examples are the expression of genes in eukaryotic cells where long chromosomal regions can adopt persistent and heritable silenced or active states, that may be associated…

Molecular Networks · Quantitative Biology 2015-05-18 Mille A. Micheelsen , Namiko Mitarai , Kim Sneppen , Ian. B. Dodd

In any ecosystem, the conditions of the environment and the characteristics of the species that inhabit it are entangled, co-evolving in space and time. We introduce a model that couples active agents with a dynamic environment, interpreted…

Populations and Evolution · Quantitative Biology 2025-12-10 G. Briozzo , G. J. Sibona , F. Peruani

Many-body long-range interacting systems can remain approximately in a quasi-stationary state far-from-thermodynamic equilibrium. These states are typically characterized by a pair of counter-propagating density clusters, or by a single…

Pattern Formation and Solitons · Physics 2022-12-20 Danilo M. Rivera , Roberto E. Navarro

We examine how systems in non-equilibrium steady states close to a continuous phase transition can still be described by a Landau potential if one forgoes the assumption of analyticity. In a system simultaneously coupled to several baths at…

Statistical Mechanics · Physics 2020-05-11 Camille Aron , Claudio Chamon

In systems characterized by a rough potential energy landscape, local energetic minima and saddles define a network of metastable states whose topology strongly influences the dynamics. Changes in temperature, causing the merging and…

Soft Condensed Matter · Physics 2009-07-24 Marco Baiesi , Lorenzo Bongini , Lapo Casetti , Lorenzo Tattini