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Construction of phylogenetic trees and networks for extant species from their characters represents one of the key problems in phylogenomics. While solution to this problem is not always uniquely defined and there exist multiple methods for…

Populations and Evolution · Quantitative Biology 2016-08-10 Nikita Alexeev , Max A. Alekseyev

A phylogenetic tree shows the evolutionary relationships among species. Internal nodes of the tree represent speciation events and leaf nodes correspond to species. A goal of phylogenetics is to combine such trees into larger trees, called…

Artificial Intelligence · Computer Science 2014-01-16 Neil C. A. Moore , Patrick Prosser

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

Let $\mathcal{T}$ be a rooted and weighted tree, where the weight of any node is equal to the sum of the weights of its children. The popular Treemap algorithm visualizes such a tree as a hierarchical partition of a square into rectangles,…

Computational Geometry · Computer Science 2013-12-17 Mark de Berg , Krzysztof Onak , Anastasios Sidiropoulos

Lecture hall partitions are a fundamental combinatorial structure which have been studied extensively over the past two decades. These objects have produced new results, as well as reinterpretations and generalizations of classicial…

Combinatorics · Mathematics 2018-08-21 McCabe Olsen

Starting from the data of an arbor, which is a rooted tree with vertices decorated by disjoint sets, we introduce a lattice polytope and a partial order on its lattice points. We give recursive algorithms for various classical invariants of…

Combinatorics · Mathematics 2025-08-26 Frédéric Chapoton

In mathematical phylogenetics, the time-consistent galled trees provide a simple class of rooted binary network structures that can be used to represent a variety of different biological phenomena. We study the enumerative combinatorics of…

Combinatorics · Mathematics 2025-04-24 Lily Agranat-Tamir , Michael Fuchs , Bernhard Gittenberger , Noah A. Rosenberg

A recurring theme in the least squares approach to phylogenetics has been the discovery of elegant combinatorial formulas for the least squares estimates of edge lengths. These formulas have proved useful for the development of efficient…

Combinatorics · Mathematics 2009-11-13 Radu Mihaescu , Lior Pachter

In this work we study the interleaving distance between merge trees from a combinatorial point of view. We use a particular type of matching between trees to obtain a novel formulation of the distance. With such formulation, we tackle the…

Combinatorics · Mathematics 2024-11-11 Matteo Pegoraro

There is a very extensive literature dealing with convex polytopes from the standpoints of combinatorics and numerical analysis. By contrast, the current paper adopts an alternative viewpoint that regards a polytope as an autonomous space…

Metric Geometry · Mathematics 2026-03-11 Anna B. Romanowska , Jonathan D. H. Smith , Anna Zamojska-Dzienio

Phylogenetic trees provide a fundamental representation of evolutionary relationships, yet the combinatorial explosion of possible tree topologies renders inference computationally challenging. Classical approaches to characterizing tree…

Populations and Evolution · Quantitative Biology 2025-12-29 Samir Bhatt , John Sabol , Papri Dey , Matthew J. Penn , David Duchene , Ruriko Yoshida

Boltzmann samplers and the recursive method are prominent algorithmic frameworks for the approximate-size and exact-size random generation of large combinatorial structures, such as maps, tilings, RNA sequences or various tree-like…

Combinatorics · Mathematics 2017-10-31 Maciej Bendkowski , Olivier Bodini , Sergey Dovgal

Tree structures appear in many fields of the life sciences, including phylogenetics, developmental biology and nucleic acid structures. Trees can be used to represent RNA secondary structures, which directly relate to the function of…

Machine Learning · Computer Science 2026-01-22 Pengyu Liu , Mariel Vázquez , Nataša Jonoska

Topological phylogenetic trees can be assigned edge weights in several natural ways, highlighting different aspects of the tree. Here the rooted triple and quartet metrizations are introduced, and applied to formulate novel fast methods of…

Populations and Evolution · Quantitative Biology 2019-05-15 John A. Rhodes

Polyhedral Omega is a new algorithm for solving linear Diophantine systems (LDS), i.e., for computing a multivariate rational function representation of the set of all non-negative integer solutions to a system of linear equations and…

Combinatorics · Mathematics 2015-02-02 Felix Breuer , Zafeirakis Zafeirakopoulos

A metric phylogenetic tree relating a collection of taxa induces weighted rooted triples and weighted quartets for all subsets of three and four taxa, respectively. New intertaxon distances are defined that can be calculated from these…

Populations and Evolution · Quantitative Biology 2020-02-12 Samaneh Yourdkhani , John A. Rhodes

The phylogenetic tree space introduced by Billera, Holmes, and Vogtmann (BHV tree space) is a CAT(0) continuous space that represents trees with edge weights with an intrinsic geodesic distance measure. The geodesic distance measure unique…

Quantitative Methods · Quantitative Biology 2021-10-29 Yingying Ren , Sihan Zha , Jingwen Bi , José A. Sanchez , Cara Monical , Michelle Delcourt , Rosemary K. Guzman , Ruth Davidson

Discrete dynamical systems defined by the iteration of a polynomial map of the unit simplex to itself appear in the context of population genetic systems evolving under mutation, recombination and weak selection. Although exceptional…

Dynamical Systems · Mathematics 2013-07-15 Sergio Lukic

Ultametrics are an important class of distances used in applications such as phylogenetics, clustering and classification theory. Ultrametrics are essentially distances that can be represented by an edge-weighted rooted tree so that all of…

Combinatorics · Mathematics 2026-02-13 Katharina T. Huber , Vincent Moulton , Guillaume E. Scholz

In this expository article we give an introduction to Ehrhart theory, i.e., the theory of integer points in polyhedra, and take a tour through its applications in enumerative combinatorics. Topics include geometric modeling in…

Combinatorics · Mathematics 2014-07-23 Felix Breuer