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At stationary environmental conditions, a catalyst's reaction rates may be restricted by thermodynamic laws, and certain performances can never be achieved (e.g., catalysts can not change the free energy difference between reactants and…

Statistical Mechanics · Physics 2023-08-21 Zhongmin Zhang , Zhiyue Lu

We analyzed the stochastic behavior of systems controlled by autocatalytic reaction A+X -> X+X. Assuming the distribution of reacting particles in the system volume to be uniform, we introduced the notion of the point model of reaction…

Statistical Mechanics · Physics 2007-05-23 L. Pal

Causal machine learning has the potential to revolutionize decision-making by combining the predictive power of machine learning algorithms with the theory of causal inference. However, these methods remain underutilized by the broader…

Polynomial dynamical systems are widely used to model and study real phenomena. In biochemistry, they are the preferred choice for modelling the concentration of chemical species in reaction networks with mass-action kinetics. These systems…

Algebraic Geometry · Mathematics 2014-12-30 Elisenda Feliu

We consider a general class of autocatalytic reactions, that has been shown to display stochastically switching behaviour (Discreteness Induced Transitions) in some parameter regimes. This behaviour was shown to occur when either the…

Probability · Mathematics 2023-12-01 Cameron Gallinger , Lea Popovic

While fields like Artificial Life have made huge strides in quantifying the mechanisms that distinguish living systems from non-living ones, particular mechanisms remain difficult to reproduce in silico. Known as open-endedness, we've been…

Biological Physics · Physics 2024-07-18 Alyssa M Adams , Eliott Jacopin , Praful Gagrani , Olaf Witkowski

Stochasticity is a key characteristic of intracellular processes such as gene regulation and chemical signalling. Therefore, characterising stochastic effects in biochemical systems is essential to understand the complex dynamics of living…

Molecular Networks · Quantitative Biology 2019-03-04 David J. Warne , Ruth E. Baker , Matthew J. Simpson

One of the basic frameworks in science views behavioral products as a process within a dynamic system. The mechanism might be seen as a representation of many instances of centralized control in real time. Many real systems, however,…

Dynamical Systems · Mathematics 2019-08-19 Chulwook Park

Autocatalysis is thought to have played an important role in the earliest stages of the origin of life. An autocatalytic cycle (AC) is a set of reactions that results in stoichiometric increase in its constituent chemicals. When the…

Populations and Evolution · Quantitative Biology 2024-07-29 Alex M. Plum , Christopher P. Kempes , Zhen Peng , David A. Baum

Causal discovery for dynamical systems poses a major challenge in fields where active interventions are infeasible. Most methods used to investigate these systems and their associated benchmarks are tailored to deterministic,…

Machine Learning · Computer Science 2025-10-13 Benjamin Herdeanu , Juan Nathaniel , Carla Roesch , Jatan Buch , Gregor Ramien , Johannes Haux , Pierre Gentine

The managed-metabolism hypothesis suggests that a cooperation barrier must be overcome if self-producing chemical organizations are to transition from non-life to life. This barrier prevents un-managed, self-organizing, autocatalytic…

Populations and Evolution · Quantitative Biology 2018-08-06 John E. Stewart

The potential benefits of autonomous systems have been driving intensive development of such systems, and of supporting tools and methodologies. However, there are still major issues to be dealt with before such development becomes…

Software Engineering · Computer Science 2022-05-25 David Harel , Assaf Marron , Joseph Sifakis

An autocatalytic pattern matching polymer system is studied as an abstract model for chemical ecosystem evolution. Highly ordered populations with particular sequence patterns appear spontaneously out of a vast number of possible states.…

Molecular Networks · Quantitative Biology 2015-06-17 Shinpei Tanaka , Harold Fellermann , Steen Rasmussen

An important transition after the origin of life was the first emergence of a Darwinian population, self-reproducing entities exhibiting differential reproduction, phenotypic variation, and inheritance of phenotypic traits. The simplest…

Biological Physics · Physics 2022-11-08 Yoshiya J. Matsubara , Sandeep Ameta , Shashi Thutupalli , Philippe Nghe , Sandeep Krishna

Stochastic processes have found numerous applications in science, as they are broadly used to model a variety of natural phenomena. Due to their intrinsic randomness and uncertainty, they are, however, difficult to characterize. Here, we…

Formalizing self reproduction in dynamical hierarchies is one of the important problems in Artificial Life (AL) studies. We study, in this paper, an inductively defined algebraic framework for self reproduction on macroscopic organizational…

Artificial Intelligence · Computer Science 2018-06-26 Janardan Misra

We provide an explicit method to construct dynamical systems which admit an a-priori prescribed attracting set. As application, we provide a method to construct perturbations of conservative dynamical systems, which admit an a-priori…

Dynamical Systems · Mathematics 2020-03-10 Razvan M. Tudoran

Learning governing dynamics from data is a common goal across the sciences, yet it is only well-posed when the underlying mechanisms are identifiable. In practice, many data-driven methods implicitly assume identifiability; when this…

Machine Learning · Computer Science 2026-05-13 Aybüke Ulusarslan , Niki Kilbertus , Nora Schneider

To cope with real-world dynamics, an intelligent system needs to incrementally acquire, update, accumulate, and exploit knowledge throughout its lifetime. This ability, known as continual learning, provides a foundation for AI systems to…

Machine Learning · Computer Science 2024-02-07 Liyuan Wang , Xingxing Zhang , Hang Su , Jun Zhu

Developing a mathematical understanding of autocatalysis in reaction networks has both theoretical and practical implications. We review definitions of autocatalytic networks and prove some properties for minimal autocatalytic subnetworks…

Molecular Networks · Quantitative Biology 2023-11-14 Praful Gagrani , Victor Blanco , Eric Smith , David Baum
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