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Spike Timing Dependent Plasticity is form of learning that has been demonstrated in real cortical tissue, but attempts to use it for artificial systems have not produced good results. This paper seeks to remedy this with two significant…

Neural and Evolutionary Computing · Computer Science 2020-07-01 Simon Davidson , Stephen B. Furber , Oliver Rhodes

Describing the collective activity of neural populations is a daunting task: the number of possible patterns grows exponentially with the number of cells, resulting in practically unlimited complexity. Recent empirical studies, however,…

Neurons and Cognition · Quantitative Biology 2012-02-02 Andrea K. Barreiro , Julijana Gjorgjieva , Fred Rieke , Eric Shea-Brown

Single unit recordings in the human medial temporal lobe (MTL) have revealed a population of cells with conceptually based, highly selective activity, indicating the presence of a sparse neural code. Building off previous work by the author…

Neurons and Cognition · Quantitative Biology 2015-08-19 Andrew Magyar

Neural decoding is still a challenge and hot topic in neurocomputing science. Recently, many studies have shown that brain network patterns containing rich spatial and temporal structure information, which represents the activation…

Neurons and Cognition · Quantitative Biology 2022-11-24 Chunyu Liu , Jiacai Zhang

Understanding how the complex connectivity structure of the brain shapes its information-processing capabilities is a long-standing question. By focusing on a paradigmatic architecture, we study how the neural activity of excitatory and…

Statistical Mechanics · Physics 2024-10-18 Giacomo Barzon , Daniel Maria Busiello , Giorgio Nicoletti

According to the theory of efficient coding, sensory systems are adapted to represent natural scenes with high fidelity and at minimal metabolic cost. Testing this hypothesis for sensory structures performing non-linear computations on high…

Neurons and Cognition · Quantitative Biology 2018-04-13 Ulisse Ferrari , Christophe Gardella , Olivier Marre , Thierry Mora

Animals learn to predict external contingencies from experience through a process of conditioning. A natural mechanism for conditioning is stimulus substitution, whereby the neuronal response to a stimulus with no prior behavioral…

Neurons and Cognition · Quantitative Biology 2024-09-23 Pantelis Vafidis , Antonio Rangel

In cognition, response times and choices in decision-making tasks are commonly modeled using Drift Diffusion Models (DDMs), which describe the accumulation of evidence for a decision as a stochastic process, specifically a Brownian motion,…

Machine Learning · Computer Science 2025-06-12 Sophie Jaffard , Giulia Mezzadri , Patricia Reynaud-Bouret , Etienne Tanré

Neurons can code for multiple variables simultaneously and neuroscientists are often interested in classifying neurons based on their receptive field properties. Statistical models provide powerful tools for determining the factors…

Neurons and Cognition · Quantitative Biology 2022-10-28 Mehrad Sarmashghi , Shantanu P. Jadhav , Uri T. Eden

Repeating spatiotemporal spike patterns exist and carry information. Here we investigated how a single spiking neuron can optimally respond to one given pattern (localist coding), or to either one of several patterns (distributed coding,…

Neural and Evolutionary Computing · Computer Science 2018-09-24 Timothée Masquelier , Saeed Reza Kheradpisheh

At the single-neuron level, precisely timed spikes can either constitute firing-rate codes or spike-pattern codes that utilize the relative timing between consecutive spikes. There has been little experimental support for the hypothesis…

Neurons and Cognition · Quantitative Biology 2009-12-18 Hugo Gabriel Eyherabide , Ariel Rokem , Andreas V. M. Herz , Ines Samengo

Recent advances in experimental techniques have allowed the simultaneous recording of populations of hundreds of neurons, allowing more comprehensive investigation into the nature of the collective structure of population neural activity.…

Neurons and Cognition · Quantitative Biology 2018-02-07 Mark L. Ioffe , Michael J. Berry

The activity of ensembles of simultaneously recorded neurons can be represented as a set of points in the space of firing rates. Even though the dimension of this space is equal to the ensemble size, neural activity can be effectively…

Neurons and Cognition · Quantitative Biology 2016-03-17 Luca Mazzucato , Alfredo Fontanini , Giancarlo La Camera

Understanding how the dynamics of neural networks is shaped by the computations they perform is a fundamental question in neuroscience. Recently, the framework of efficient coding proposed a theory of how spiking neural networks can compute…

Neurons and Cognition · Quantitative Biology 2022-10-25 Veronika Koren , Stefano Panzeri

Animals learn tasks requiring a sequence of actions over time. Waiting a given time before taking an action is a simple example. Mimicry is a complex example, e.g. in humans, humming a brief tune you have just heard. Re-experiencing a…

Neurons and Cognition · Quantitative Biology 2009-10-15 J. J. Hopfield , Carlos D. Brody

Brains learn to represent information from a large set of stimuli, typically by weak supervision. Unsupervised learning is therefore a natural approach for exploring the design of biological neural networks and their computations.…

Neurons and Cognition · Quantitative Biology 2025-10-17 Roy Urbach , Elad Schneidman

Neuronal responses are conspicuously variable. We focus on one particular aspect of that variability: the precision of action potential timing. We show that for common models of noisy spike generation, elementary considerations imply that…

Disordered Systems and Neural Networks · Physics 2009-10-31 Guillermo A. Cecchi , Mariano Sigman , Jose-Manuel Alonso , Luis Martinez , Dante R. Chialvo , Marcelo O. Magnasco

We designed a model-based analysis to predict the occurrence of population patterns in distributed spiking activity. Using a maximum entropy principle with a Markovian assumption, we obtain a model that accounts for both spatial and…

Neurons and Cognition · Quantitative Biology 2009-11-13 Olivier Marre , Sami El Boustani , Yves Fregnac , Alain Destexhe

A fundamental problem in neuroscience is to characterize the dynamics of spiking from the neurons in a circuit that is involved in learning about a stimulus or a contingency. A key limitation of current methods to analyze neural spiking…

Methodology · Statistics 2017-09-29 Yingzhuo Zhang , Noa Malem-Shinitski , Stephen A Allsop , Kay Tye , Demba Ba

The manner in which groups of neurons represent events in the external world is fundamental to neuroscience. Here, we analyze the population code of the retina during naturalistic stimulation and show that the information conveyed by…

Neurons and Cognition · Quantitative Biology 2007-05-23 Elad Schneidman , Jason L. Puchalla , Ronen Segev , Robert A. Harris , William Bialek , Michael J. Berry