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Resolvable designs with two blocks per replicate are studied from an optimality perspective. Because in practice the number of replicates is typically less than the number of treatments, arguments can be based on the dual of the information…

Statistics Theory · Mathematics 2009-09-29 J. P. Morgan , Brian H. Reck

Balanced incomplete block designs (BIBDs) are a class of designs with v treatments and b blocks of size k that are optimal with regards to a wide range of optimality criteria, but it is not clear which designs to choose for combinations of…

Statistics Theory · Mathematics 2019-02-13 Sera Aylin Cakiroglu , Peter J Cameron

The dimension of a block design is the maximum positive integer $d$ such that any $d$ of its points are contained in a proper subdesign. Pairwise balanced designs PBD$(v,K)$ have dimension at least two as long as not all points are on the…

Combinatorics · Mathematics 2019-07-22 Coen del Valle , Peter J. Dukes

We investigate block designs, under the A- and MV-criteria, when each treatment can have only one or two replications due to resource constraints, as can happen, for example, in early generation varietal trials. While these are commonly…

Statistics Theory · Mathematics 2026-03-25 R. A. Bailey , Rahul Mukerjee

Optimal block designs in small blocks are explored when the treatments have a natural ordering and interest lies in comparing consecutive pairs of treatments. We first develop an approximate theory which leads to a convenient multiplicative…

Statistics Theory · Mathematics 2014-05-20 S. Huda , Rahul Mukerjee

We develop $D$-optimal designs for linear models with first-order interactions on a subset of the $2^K$ full factorial design region, when both the number of factors set to the higher level and the number of factors set to the lower level…

Statistics Theory · Mathematics 2019-05-14 Fritjof Freise , Rainer Schwabe

In a tie-breaker design (TBD), subjects with high values of a running variable are given some (usually desirable) treatment, subjects with low values are not, and subjects in the middle are randomized. TBDs are intermediate between…

Methodology · Statistics 2025-05-12 Tim P. Morrison , Art B. Owen

We consider experiments for comparing treatments using units that are ordered linearly over time or space within blocks. In addition to the block effect, we assume that a trend effect influences the response. The latter is modeled as a…

Statistics Theory · Mathematics 2008-12-18 Dibyen Majumdar , John Stufken

In multi-response regression models, the error covariance matrix is never known in practice. Thus, there is a need for optimal designs which are robust against possible misspecification of the error covariance matrix. In this paper, we…

Methodology · Statistics 2019-10-03 Lucy L. Gao , Julie Zhou

This paper studies circular designs for interference models, where a treatment assigned to a plot also affects its neighboring plots within a block. For the purpose of estimating total effects, the circular neighbor balanced design was…

Methodology · Statistics 2022-06-02 Xiangshun Kong , Xueru Zhang , Wei Zheng

For a connected graph $G$ with order $n$, let $e(G)$ be the number of its distinct eigenvalues and $d$ be the diameter. We denote by $m_G(\mu)$ the eigenvalue multiplicity of $\mu$ in $G$. It is well known that $e(G)\geq d+1$, which shows…

Spectral Theory · Mathematics 2023-11-27 Yuanshuai Zhang , Dein Wong , Wenhao Zhen

A typical problem in optimal design theory is finding an experimental design that is optimal with respect to some criteria in a class of designs. The most popular criteria include the A- and D-criteria. Regular graph designs occur in many…

Computation · Statistics 2015-04-20 Sera Aylin Cakiroglu

For the majority of run sizes N where N <= 20, the literature reports the best D- and A-optimal designs for the main-effects model which sequentially minimizes the aliasing between main effects and interaction effects and among interaction…

Methodology · Statistics 2025-12-25 Mohammed Saif Ismail Hameed , Eric D. Schoen , Jose Nunez Ares , Peter Goos

The Hadamard maximal determinant (maxdet) problem is to find the maximum determinant D(n) of a square {+1, -1} matrix of given order n. Such a matrix with maximum determinant is called a saturated D-optimal design. We consider some cases…

Combinatorics · Mathematics 2014-07-30 Richard P. Brent

Consider a given square matrix $\textrm {K}$ with square blocks $A_{11},A_{22},\ldots,A_{nn}$ on the main diagonal. This paper aims to compute an optimal perturbation $\Delta$ of a preassigned block $A_{ii}\in\mathbb{C}^{d_i\times d_k},…

Numerical Analysis · Mathematics 2025-10-22 M. R. Eslahchi , E. Kokabifar

In optimal experimental design, the objective is to select a limited set of experiments that maximizes information about unknown model parameters based on factor levels. This work addresses the generalized D-optimal design problem, allowing…

Data Structures and Algorithms · Computer Science 2024-11-05 Aditya Pillai , Gabriel Ponte , Marcia Fampa , Jon Lee , and Mohit Singh , Weijun Xie

We introduce a minor variant of the approximate D-optimal design of experiments with a more general information matrix that takes into account the representation of the design space S. The main motivation (and result) is that if S in R^d is…

Optimization and Control · Mathematics 2025-05-15 Didier Henrion , Jean Bernard Lasserre

We consider optimal non-sequential designs for a large class of (linear and nonlinear) regression models involving polynomials and rational functions with heteroscedastic noise also given by a polynomial or rational weight function. The…

Computation · Statistics 2011-08-30 Dávid Papp

We study a class of spectral design problems in which a prior positive semidefinite information matrix is updated by a sum of rank-one matrices constructed from chosen design vectors subject to a bound on their Euclidean norm. The objective…

Optimization and Control · Mathematics 2026-05-28 Anton J. Kleywegt , Johannes Milz , Mohit Singh , Weijun Xie

We consider a distributed computing system in which a master node coordinates $N$ workers to evaluate a function over $n$ input files, where this function accepts general decomposition. In particular, we focus on the general case where the…

Information Theory · Computer Science 2026-04-21 Javad Maheri , K. K. Krishnan Namboodiri , Petros Elia
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