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The response of the immune system to different vaccination patterns is studied with a simple model. It is argued that the history and characteristics of the pattern defines very different secondary immune responses in the case of infection.…

Other Quantitative Biology · Quantitative Biology 2009-11-10 P. Etchegoin

Preventing infectious disease like flu from spreading to large communities is one of the most important issues for humans. One effective strategy is voluntary vaccination, however, there is always the temptation for people refusing to be…

Populations and Evolution · Quantitative Biology 2017-04-07 Genki Ichinose , Takehiro Kurisaku

The commonly observed negative correlation between the number of species in an ecological community and disease risk, typically referred to as "the dilution effect", has received a substantial amount of attention over the past decade.…

Populations and Evolution · Quantitative Biology 2020-01-22 Peter Shaffery , Bret D. Elderd , Vanja Dukic

This work consists of an epidemic model with vaccination coupled with an opinion dynamics. Our objective was to study how disease risk perception can influence opinions about vaccination and therefore the spreading of the disease.…

Physics and Society · Physics 2019-11-20 Marcelo A. Pires , André L. Oestereich , Nuno Crokidakis

We study the effect of migration between coupled populations, or patches, on the stability properties of multistrain disease dynamics. The epidemic model used in this work displays a Hopf bifurcation to oscillations in a single well mixed…

Populations and Evolution · Quantitative Biology 2009-07-29 Simone Bianco , Leah B. Shaw

We investigate stochastic extinction in an epidemic model and the impact of random vaccinations in large populations. We show that, in the absence of vaccinations, the effective entropic barrier for extinction displays scaling with the…

Biological Physics · Physics 2009-11-13 Mark Dykman , Ira B. Schwartz , Alexandra S. Landsman

SIRS epidemic models assume that individual immunity (from infection and vaccination) wanes in one big leap, from complete immunity to complete susceptibility. For many diseases immunity on the contrary wanes gradually, something that's…

Populations and Evolution · Quantitative Biology 2022-11-17 Mohamed El Khalifi , Tom Britton

The spreading of Covid-19 pandemic has highlighted the close link between economics and health in the context of emergency management. A widespread vaccination campaign is considered the main tool to contain the economic consequences. This…

Physics and Society · Physics 2022-02-09 Emanuele Bernardi , Lorenzo Pareschi , Giuseppe Toscani , Mattia Zanella

We study supercritical spatial SIR epidemics on $\mathbb{Z}^2\times \{1,2,\ldots, N\}$, where each site in $\mathbb{Z}^2$ represents a village and $N$ stands for the village size. We establish several key asymptotic results as $N\to\infty$.…

Probability · Mathematics 2021-12-01 Xinghua Zheng , Qingsan Zhu

In this paper we introduce an approach to the management of infectious disease diffusion through the formulation of a controlled compartmental SVIR (Susceptible-Vaccinated-Infected-Recovered) model. We consider a cost functional…

Optimization and Control · Mathematics 2023-11-28 Alessandro Ramponiand M. Elisabetta Tessitore

We consider a SIR model with temporary immunity and time dependent transmission rate. We assume time dependent vaccination which confers the same immunity as natural infection. We study two types of vaccination strategies: i) optimal…

Populations and Evolution · Quantitative Biology 2016-04-06 Paulo Doutor , Paula Rodrigues , Maria do Céu Soares , Fabio A. C. C. Chalub

In this work we analyze the evolution of voluntary vaccination in networked populations by entangling the spreading dynamics of an influenza-like disease with an evolutionary framework taking place at the end of each influenza season so…

Physics and Society · Physics 2013-09-11 Alessio Cardillo , Catalina Reyes-Suárez , Fernando Naranjo , Jesús Gómez-Gardeñes

Infectious pathogens often propagate by superspreading, which focusses onward transmission on disproportionately few infected individuals. At the same time, infector-infectee pairs tend to have more similar transmission potentials than…

Populations and Evolution · Quantitative Biology 2025-09-22 Noah Silva de Leonardi , Benjamin D. Dalziel

We study the SIRS (Susceptible-Infected-Recovered-Susceptible) spreading processes over complex networks, by considering its exact $3^n$-state Markov chain model. The Markov chain model exhibits an interesting connection with its $2n$-state…

Social and Information Networks · Computer Science 2016-03-17 Navid Azizan Ruhi , Babak Hassibi

Seasonal influenza presents an ongoing challenge to public health. The rapid evolution of the flu virus necessitates annual vaccination campaigns, but the decision to get vaccinated or not in a given year is largely voluntary, at least in…

Populations and Evolution · Quantitative Biology 2021-01-21 Irena Papst , Kevin P. O'Keeffe , Steven H. Strogatz

We propose a model of the immunity to a cyclical epidemic disease taking account not only of seasonal boosts during the infectious season, but also of residual immunity remaining from one season to the next. The focus is on the exponential…

Populations and Evolution · Quantitative Biology 2024-04-22 Siyu Chen , David Sankoff

Infectious disease outbreaks have precipitated a profusion of mathematical models. Epidemic curves predicted by these models are typically qualitatively similar, despite distinct model assumptions, but there is no theoretical explanation…

Populations and Evolution · Quantitative Biology 2026-02-23 David J. D. Earn , Todd L. Parsons

The transmission dynamics of Tuberculosis (TB) involve complex epidemiological and socio-economical interactions between individuals living in highly distinct regional conditions. The level of exogenous reinfection and first time infection…

Populations and Evolution · Quantitative Biology 2016-09-15 Victor Moreno , Baltazar Espinoza , Kamal Barley , Marlio Paredes , Derdei Bichara , Anuj Mubayi , Carlos Castillo-Chavez

We consider an epidemiological model that includes waning and boosting of immunity. Assuming that repeated exposure to the pathogen fully restores immunity, we derive an SIRS-type model with discrete and distributed delays. First we prove…

Dynamical Systems · Mathematics 2016-06-14 Maria Vittoria Barbarossa , Monika Polner , Gergely Röst

Contact patterns in populations fundamentally influence the spread of infectious diseases. Current mathematical methods for epidemiological forecasting on networks largely assume that contacts between individuals are fixed, at least for the…

Populations and Evolution · Quantitative Biology 2007-05-23 Erik Volz , Lauren Ancel Meyers
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