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The formula for the probability of fixation of a new mutation is widely used in theoretical population genetics and molecular evolution. Here we derive a series of identities, inequalities and approximations for the exact probability of…

Populations and Evolution · Quantitative Biology 2015-03-10 David M. McCandlish , Charles L. Epstein , Joshua B. Plotkin

Motivated by the wide range of known self-replicating systems, some far from genetics, we study a system composed by individuals having an internal dynamics with many possible states that are partially stable, with varying mutation rates.…

Biological Physics · Physics 2015-10-07 Tommaso Brotto , Guy Bunin , Jorge Kurchan

We study the asymptotic distribution of the number of matchings of size $\ell=\ell(n)$ in $G(n,p)$ for a wide range of $p=p(n)\in (0,1)$ and for every $1\le \ell\le \lfloor n/2\rfloor$. We prove that this distribution changes from normal to…

Combinatorics · Mathematics 2015-08-05 Pu Gao , Cristiane M. Sato

This article studies the quasi-stationary behaviour of population processes with unbounded absorption rate, including one-dimensional birth and death processes with catastrophes and multi-dimensional birth and death processes, modeling…

Probability · Mathematics 2016-11-10 Nicolas Champagnat , Denis Villemonais

We model evolution according to an asymmetric game as occurring in multiple finite populations, one for each role in the game, and study the effect of subjecting individuals to stochastic strategy mutations. We show that, when these…

Populations and Evolution · Quantitative Biology 2015-12-22 Carl Veller , Laura K. Hayward

This chapter focuses on the derivation of a doubly nonlocal Fisher-KPP model, which is a macroscopic nonlocal evolution equation describing population dynamics in the large population limit. The derivation starts from a microscopic…

Analysis of PDEs · Mathematics 2024-06-11 Jasper Hoeksema , Anastasiia Hraivoronska , Oliver Tse

A particular case of the famous quasispecies model - the Crow-Kimura model with a permutation invariant fitness landscape - is investigated. Using the fact that the mutation matrix in the case of a permutation invariant fitness landscape…

Populations and Evolution · Quantitative Biology 2014-08-21 Alexander S. Bratus , Artem S. Novozhilov , Yuri S. Semenov

Threshold values in population dynamics can be formulated as spectral bounds of matrices, determining the dichotomy of population persistence and extinction. For a square matrix $\mu A + Q$, where $A$ is a quasi-positive matrix describing…

Dynamical Systems · Mathematics 2019-11-07 Shanshan Chen , Junping Shi , Zhisheng Shuai , Yixiang Wu

The Moran process, as studied by [Lieberman, E., Hauert, C. and Nowak, M. Evolutionary dynamics on graphs. Nature 433, pp. 312-316 (2005)], is a stochastic process modeling the spread of genetic mutations in populations. In this process,…

Populations and Evolution · Quantitative Biology 2021-07-27 Themistoklis Melissourgos , Sotiris Nikoletseas , Christoforos Raptopoulos , Paul Spirakis

Human populations have experienced dramatic growth since the Neolithic revolution. Recent studies that sequenced a very large number of individuals observed an extreme excess of rare variants, and provided clear evidence of recent rapid…

Populations and Evolution · Quantitative Biology 2015-06-17 Elodie Gazave , Li Ma , Diana Chang , Alex Coventry , Feng Gao , Donna Muzny , Eric Boerwinkle , Richard Gibbs , Charles F. Sing , Andrew G. Clark , Alon Keinan

This survey concerns the study of quasi-stationary distributions with a specific focus on models derived from ecology and population dynamics. We are concerned with the long time behavior of different stochastic population size processes…

Probability · Mathematics 2012-12-05 Sylvie Méléard , Denis Villemonais

We consider a branching process with Poissonian immigration where individuals have inheritable types. At rate theta, new individuals singly enter the total population and start a new population which evolves like a supercritical,…

Probability · Mathematics 2010-12-02 Mathieu Richard

Muller's ratchet, in its prototype version, models a haploid, asexual population whose size~$N$ is constant over the generations. Slightly deleterious mutations are acquired along the lineages at a constant rate, and individuals carrying…

Probability · Mathematics 2026-01-01 Jan Lukas Igelbrink , Charline Smadi , Anton Wakolbinger

There is mounting empirical evidence that many communities of living organisms display key features which closely resemble those of physical systems at criticality. We here introduce a minimal model framework for the dynamics of a community…

Biological Physics · Physics 2020-02-17 Fabio Peruzzo , Mauro Mobilia , Sandro Azaele

We study the convergence of the population dynamics algorithm, which produces sample pools of random variables having a distribution that closely approximates that of the {\em special endogenous solution} to a stochastic fixed-point…

Probability · Mathematics 2018-02-12 Mariana Olvera-Cravioto

In stochastic dynamical systems, different concepts of stability can be obtained in different limits. A particularly interesting example is evolutionary game theory, which is traditionally based on infinite populations, where strict Nash…

Populations and Evolution · Quantitative Biology 2007-05-23 Arne Traulsen , Jorge M. Pacheco , Lorens A. Imhof

We study the stationary state of a population evolving under the action of random genetic drift, selection and recombination in which both deleterious and reverse beneficial mutations can occur. We find that the equilibrium fraction of…

Populations and Evolution · Quantitative Biology 2016-01-13 Sona John , Kavita Jain

We study general properties of the leading eigenvalue $\overline{w}(q)$ of Eigen's evolutionary matrices depending on the probability $q$ of faithful reproduction. This is a linear algebra problem that has various applications in…

Populations and Evolution · Quantitative Biology 2014-05-27 Yuri S. Semenov , Alexander S. Bratus , Artem S. Novozhilov

We investigate the error threshold for the emergence of quasispecies in the Eigen model. By mapping to to an effective Hamiltonian ruled by the "imaginary-time" Schr\"odinger equation, a variational ansatz is proposed and applied to…

Populations and Evolution · Quantitative Biology 2010-12-08 Min-Feng Tu , Ching-I Huang , Hsiu-Hau Lin , Chun-Chung Chen

We consider a non-conserving zero-range process with hopping rate proportional to the number of particles at each site. Particles are added to the system with a site-dependent creation rate, and removed from the system with a uniform…

Statistical Mechanics · Physics 2019-09-04 Pascal Grange